BacMap

Definition	Escherichia coli SMS-3-5 chromosome, complete genome.
Accession	NC_010498
Length	5,068,389

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The map label for this gene is dbpA [H]

Identifier: 170681328

GI number: 170681328

Start: 1795569

End: 1796942

Strand: Reverse

Name: dbpA [H]

Synonym: EcSMS35_1779

Alternate gene names: 170681328

Gene position: 1796942-1795569 (Counterclockwise)

Preceding gene: 170682997

Following gene: 170680086

Centisome position: 35.45

GC content: 51.75

Gene sequence:

>1374_bases
GTGACCGCTTTTTCTACCCTGAATGTTTTGCCTCCCGCCCAACTCACGAACCTTAATGAGTTGGGTTATTTAACCATGAC
GCCGGTGCAGGCCGCCGCGCTTCCGGCGATCCTTGCCGGAAAAGATGTTCGCGTGCAGGCGAAAACCGGCAGTGGCAAAA
CGGCGGCTTTTGGCCTCGGCTTGTTACAGCAAATTGATGCGTCGCTATTTCAAACCCAGGCTTTAGTGCTGTGTCCTACG
CGTGAACTGGCGGATCAGGTGGCAGGTGAATTGCGTCGGCTGGCGCGTTTTCTGCCAAATACCAAAATTTTGACGTTGTG
CGGTGGTCAACCGTTCGGTATGCAGCGTGATTCGTTGCAACATGCGCCGCATATTATCGTGGCAACGCCGGGTCGTTTGC
TGGATCACTTGCAAAAAGGCACGGTATCACTGGATGCGCTGAATACTTTGGTGATGGATGAGGCCGACCGCATGCTGGAT
ATGGGATTTAGCGACGCCATTGATGATGTCATCCGTTTTGCGCCAGCATCTCGACAGACGCTTCTGTTTTCGGCAACCTG
GCCGGAAGCCATCGCCGCAATCAGCGGACGAGTGCAACGCGATCCTTTAGCGATTGAAATTGACTCAACAGATGCTCTGC
CTCCCATTGAACAACAATTTTATGAGACATTCAGCAAAGGCAAAATTCCGTTGTTGCAACGGTTATTAAGTTTGCATCAG
CCATCCTCTTGCGTGGTGTTTTGCAATACCAAAAAAGATTGCCAGGCTGTCTGTGACGCGCTGAATGAAGTAGGGCAAAG
TGCATTGTCGTTACACGGCGATCTGGAGCAACGCGATCGCGATCAGACTCTGGTACGTTTTGCTAACGGTAGCGCCCGTG
TACTGGTCGCGACTGATGTTGCTGCGCGTGGTCTGGATATTAAATCGCTTGAGCTGGTAGTGAACTTTGAACTGGCGTGG
GACCCTGAAGTTCATGTACATCGCATCGGTCGTACAGCGCGTGCAGGAAATAGCGGTCTGGCGATCAGTTTCTGTGCCCC
GGAAGAAGCACAGCGGGCCAATATCATTTCTGACATGTTGCAGATAAAACTTAACTGGCAAACGCCGCCAGCTAATAGTT
CCATTGTGCCGCTGGAAGCCGAAATGGCAACGTTATGTATCGATGGCGGGAAAAAAGCCAAAATGCGCCCGGGTGATGTA
TTAGGTGCGCTGACAGGAGATATCGGGCTTGATGGCGCAGATATTGGCAAAATCGCCGTGCATCCGGCGCATGTCTATGT
CGCGGTGCGTCAGGCTGTTGCTCATAAAGCATGGAAACAGTTACAGGGCGGGAAGATTAAAGGAAAAACGTGCCGGGTGC
GGTTATTAAAATAA

Upstream 100 bases:

>100_bases
CACCCCCCGATGAAGAACCGATTAAATTGTCGCATCGTGAGCGTAGATCTGCGAGGATACGTGCCTGCTGACTTTGCGTC
GATGACCACGAGAATAGATT

Downstream 100 bases:

>100_bases
TGAAATGTTGAATCGCAGGGTGCAAGAGTCAATATCTTCTTCGGGATTGCCGGATGCGACGCTGGCCGCGTCTTCTCCGG
CCTCCATAAGAGTAGCCCGA

Product: ATP-dependent RNA helicase DbpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPT
RELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETFSKGKIPLLQRLLSLHQ
PSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAW
DPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKKAKMRPGDV
LGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK

Sequences:

>Translated_457_residues
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPT
RELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETFSKGKIPLLQRLLSLHQ
PSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAW
DPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKKAKMRPGDV
LGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK
>Mature_456_residues
TAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTR
ELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDM
GFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETFSKGKIPLLQRLLSLHQP
SSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWD
PEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKKAKMRPGDVL
GALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK

Specific function: Has a helix-destabilizing activity, which is not coupled to the ATPase activity. Can unwind the 23S rRNA as well as 16S rRNA. Exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA. Could play a major role in ribosome ass

COG id: COG0513

COG function: function code LKJ; Superfamily II DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI31542656, Length=374, Percent_Identity=37.4331550802139, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI7661920, Length=349, Percent_Identity=33.810888252149, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI164664518, Length=358, Percent_Identity=31.2849162011173, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI224593278, Length=383, Percent_Identity=36.2924281984334, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI45446747, Length=348, Percent_Identity=36.4942528735632, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI45446743, Length=348, Percent_Identity=36.4942528735632, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI20149629, Length=349, Percent_Identity=37.5358166189112, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI41327773, Length=358, Percent_Identity=36.8715083798883, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI21071032, Length=350, Percent_Identity=37.4285714285714, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI262118318, Length=399, Percent_Identity=36.3408521303258, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI301171475, Length=382, Percent_Identity=37.434554973822, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI301171467, Length=382, Percent_Identity=37.434554973822, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI87196351, Length=382, Percent_Identity=37.434554973822, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI216548263, Length=399, Percent_Identity=36.3408521303258, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI262231852, Length=399, Percent_Identity=36.3408521303258, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI50659095, Length=385, Percent_Identity=34.2857142857143, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI169881239, Length=373, Percent_Identity=37.5335120643432, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI13514809, Length=373, Percent_Identity=37.5335120643432, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI13518015, Length=399, Percent_Identity=36.3408521303258, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI148613856, Length=372, Percent_Identity=34.6774193548387, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI38201710, Length=372, Percent_Identity=34.6774193548387, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4758138, Length=349, Percent_Identity=35.243553008596, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI4758112, Length=362, Percent_Identity=30.3867403314917, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI18375623, Length=362, Percent_Identity=30.3867403314917, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI21040371, Length=361, Percent_Identity=30.4709141274238, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI38327634, Length=361, Percent_Identity=36.2880886426593, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI41327771, Length=379, Percent_Identity=34.0369393139842, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI13129006, Length=347, Percent_Identity=35.1585014409222, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI222352149, Length=363, Percent_Identity=34.9862258953168, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI83700235, Length=351, Percent_Identity=34.1880341880342, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4503529, Length=352, Percent_Identity=34.0909090909091, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI188035877, Length=344, Percent_Identity=36.9186046511628, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI51094101, Length=352, Percent_Identity=34.375, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI164419743, Length=352, Percent_Identity=34.375, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI55749865, Length=351, Percent_Identity=31.3390313390313, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI41327779, Length=397, Percent_Identity=32.4937027707809, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI256223453, Length=364, Percent_Identity=31.8681318681319, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI13514831, Length=379, Percent_Identity=34.3007915567282, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI41327776, Length=348, Percent_Identity=33.3333333333333, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI164419732, Length=373, Percent_Identity=31.0991957104558, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI8922886, Length=348, Percent_Identity=30.4597701149425, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI6005743, Length=348, Percent_Identity=30.4597701149425, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI62241022, Length=337, Percent_Identity=30.5637982195846, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI17505907, Length=421, Percent_Identity=30.8788598574822, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI9506931, Length=391, Percent_Identity=29.156010230179, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI62241024, Length=360, Percent_Identity=30, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI38569503, Length=359, Percent_Identity=27.8551532033426, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4826686, Length=338, Percent_Identity=28.9940828402367, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI38569505, Length=359, Percent_Identity=27.8551532033426, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI9966805, Length=308, Percent_Identity=32.4675324675325, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI256773275, Length=357, Percent_Identity=32.2128851540616, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI154759257, Length=400, Percent_Identity=29.75, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI20336298, Length=235, Percent_Identity=34.8936170212766, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1787605, Length=457, Percent_Identity=99.3435448577681, Blast_Score=924, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=349, Percent_Identity=43.5530085959885, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1787016, Length=369, Percent_Identity=39.8373983739837, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI1790214, Length=351, Percent_Identity=36.4672364672365, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1788930, Length=335, Percent_Identity=38.2089552238806, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17507121, Length=365, Percent_Identity=34.5205479452055, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71995724, Length=349, Percent_Identity=34.9570200573066, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI71987143, Length=334, Percent_Identity=35.3293413173653, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17555296, Length=365, Percent_Identity=38.3561643835616, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17510309, Length=357, Percent_Identity=38.0952380952381, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17510307, Length=357, Percent_Identity=38.0952380952381, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71995514, Length=357, Percent_Identity=38.0952380952381, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17552114, Length=350, Percent_Identity=30.8571428571429, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71982858, Length=362, Percent_Identity=30.6629834254144, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI115533224, Length=361, Percent_Identity=35.4570637119114, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI86570094, Length=353, Percent_Identity=37.1104815864023, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17507945, Length=355, Percent_Identity=36.056338028169, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17510559, Length=366, Percent_Identity=34.6994535519126, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71995718, Length=378, Percent_Identity=36.5079365079365, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17507877, Length=396, Percent_Identity=35.6060606060606, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI32565321, Length=377, Percent_Identity=34.4827586206897, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17507879, Length=387, Percent_Identity=34.1085271317829, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI115532546, Length=361, Percent_Identity=33.7950138504155, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI115532548, Length=353, Percent_Identity=34.5609065155807, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71999646, Length=344, Percent_Identity=34.593023255814, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71999644, Length=344, Percent_Identity=34.593023255814, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17552642, Length=337, Percent_Identity=34.7181008902077, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17507881, Length=408, Percent_Identity=31.3725490196078, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17537549, Length=374, Percent_Identity=32.0855614973262, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17536099, Length=412, Percent_Identity=31.5533980582524, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17536101, Length=412, Percent_Identity=31.5533980582524, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17505370, Length=339, Percent_Identity=35.3982300884956, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17536103, Length=403, Percent_Identity=31.7617866004963, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17509811, Length=347, Percent_Identity=32.5648414985591, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17553716, Length=350, Percent_Identity=30, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI193206561, Length=329, Percent_Identity=31.0030395136778, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17556951, Length=400, Percent_Identity=28.25, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71990816, Length=382, Percent_Identity=30.8900523560209, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193208216, Length=382, Percent_Identity=31.9371727748691, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17507641, Length=399, Percent_Identity=28.8220551378446, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71982862, Length=195, Percent_Identity=32.8205128205128, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25148203, Length=406, Percent_Identity=26.3546798029557, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508543, Length=359, Percent_Identity=28.9693593314763, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32564046, Length=375, Percent_Identity=29.6, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71997889, Length=397, Percent_Identity=27.455919395466, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25148291, Length=331, Percent_Identity=27.190332326284, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25148205, Length=340, Percent_Identity=25.2941176470588, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71987152, Length=82, Percent_Identity=43.9024390243902, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321360, Length=345, Percent_Identity=40.2898550724638, Blast_Score=222, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6323021, Length=360, Percent_Identity=36.3888888888889, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324217, Length=374, Percent_Identity=35.5614973262032, Blast_Score=217, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320224, Length=376, Percent_Identity=33.5106382978723, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6321856, Length=374, Percent_Identity=36.8983957219251, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6320041, Length=329, Percent_Identity=32.8267477203647, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323947, Length=361, Percent_Identity=37.3961218836565, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324778, Length=377, Percent_Identity=34.7480106100796, Blast_Score=199, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6325138, Length=368, Percent_Identity=35.054347826087, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320119, Length=356, Percent_Identity=31.1797752808989, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321963, Length=365, Percent_Identity=35.6164383561644, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322912, Length=331, Percent_Identity=33.8368580060423, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322323, Length=331, Percent_Identity=33.8368580060423, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320449, Length=375, Percent_Identity=31.4666666666667, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6321111, Length=379, Percent_Identity=33.7730870712401, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324620, Length=359, Percent_Identity=32.033426183844, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322427, Length=365, Percent_Identity=32.6027397260274, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6319618, Length=409, Percent_Identity=29.3398533007335, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320173, Length=394, Percent_Identity=31.2182741116751, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319714, Length=435, Percent_Identity=29.8850574712644, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320400, Length=356, Percent_Identity=29.2134831460674, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6321267, Length=349, Percent_Identity=30.945558739255, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323306, Length=401, Percent_Identity=26.1845386533666, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324366, Length=352, Percent_Identity=25.5681818181818, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321374, Length=413, Percent_Identity=23.4866828087167, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322876, Length=159, Percent_Identity=34.5911949685535, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24584399, Length=356, Percent_Identity=38.7640449438202, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24645031, Length=365, Percent_Identity=33.6986301369863, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24642151, Length=357, Percent_Identity=35.5742296918768, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI21356161, Length=389, Percent_Identity=34.4473007712082, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI17136814, Length=363, Percent_Identity=37.7410468319559, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI28574962, Length=394, Percent_Identity=35.0253807106599, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24585582, Length=345, Percent_Identity=36.5217391304348, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI28575014, Length=340, Percent_Identity=36.4705882352941, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI17985987, Length=367, Percent_Identity=38.1471389645777, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24583281, Length=335, Percent_Identity=33.134328358209, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24583279, Length=335, Percent_Identity=33.134328358209, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24644487, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI45551833, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24644485, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24644483, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI281361218, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24644481, Length=384, Percent_Identity=34.8958333333333, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24662330, Length=368, Percent_Identity=35.5978260869565, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24644479, Length=384, Percent_Identity=34.8958333333333, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI18857967, Length=370, Percent_Identity=34.3243243243243, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24582080, Length=375, Percent_Identity=33.8666666666667, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24582078, Length=375, Percent_Identity=33.8666666666667, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI17136248, Length=375, Percent_Identity=33.8666666666667, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24582075, Length=375, Percent_Identity=33.8666666666667, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI17977678, Length=349, Percent_Identity=35.243553008596, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24581954, Length=387, Percent_Identity=30.4909560723514, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24581952, Length=387, Percent_Identity=30.4909560723514, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24581956, Length=387, Percent_Identity=30.4909560723514, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21355075, Length=363, Percent_Identity=33.0578512396694, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24584994, Length=377, Percent_Identity=32.6259946949602, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI28571808, Length=358, Percent_Identity=34.0782122905028, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28571809, Length=358, Percent_Identity=34.0782122905028, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281365720, Length=308, Percent_Identity=36.038961038961, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21355559, Length=373, Percent_Identity=34.5844504021448, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17647335, Length=349, Percent_Identity=29.2263610315186, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24643725, Length=388, Percent_Identity=29.1237113402062, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24642822, Length=378, Percent_Identity=30.1587301587302, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24668515, Length=331, Percent_Identity=30.2114803625378, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19920478, Length=356, Percent_Identity=30.3370786516854, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24666101, Length=370, Percent_Identity=30.8108108108108, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI20130173, Length=332, Percent_Identity=28.0120481927711, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859659, Length=231, Percent_Identity=32.9004329004329, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571338, Length=231, Percent_Identity=32.9004329004329, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24640164, Length=372, Percent_Identity=23.1182795698925, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136666, Length=222, Percent_Identity=27.4774774774775, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005580
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000629
- InterPro:   IPR014014 [H]

Pfam domain/function: PF03880 DbpA; PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 49273; Mature: 49141

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00039 DEAD_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLG
CCCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
LLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQ
HHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHC
HAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDMGFSDAIDDVIRFAPASRQT
CCCEEEEECCHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCE
LLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETFSKGKIPLLQRLLSLHQ
EEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCC
PSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDV
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCEEEEEEECH
AARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDML
HHCCCCEEEEEEEEEEEEEECCCCHHEECCCHHCCCCCCEEEEEECCCHHHHHHHHHHHH
QIKLNWQTPPANSSIVPLEAEMATLCIDGGKKAKMRPGDVLGALTGDIGLDGADIGKIAV
EEEEEECCCCCCCCEEEEECCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEE
HPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
TAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLG
CCCCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
LLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGMQRDSLQ
HHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHC
HAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLDMGFSDAIDDVIRFAPASRQT
CCCEEEEECCHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCE
LLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETFSKGKIPLLQRLLSLHQ
EEEECCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCC
PSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDV
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCEEEEEEECH
AARGLDIKSLELVVNFELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDML
HHCCCCEEEEEEEEEEEEEECCCCHHEECCCHHCCCCCCEEEEEECCCHHHHHHHHHHHH
QIKLNWQTPPANSSIVPLEAEMATLCIDGGKKAKMRPGDVLGALTGDIGLDGADIGKIAV
EEEEEECCCCCCCCEEEEECCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEE
HPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2216714; 8253085; 9097039; 9278503; 9016593; 11350034 [H]