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The map label for this gene is trmB [H]

Identifier: 170077525

GI number: 170077525

Start: 937116

End: 937766

Strand: Reverse

Name: trmB [H]

Synonym: SYNPCC7002_A0903

Alternate gene names: 170077525

Gene position: 937766-937116 (Counterclockwise)

Preceding gene: 170077528

Following gene: 170077524

Centisome position: 31.18

GC content: 45.93

Gene sequence:

>651_bases
GTGGGGCGATCGCGCGTTCGACAGCATGTCAATCCCTTAACCGATAAGTATCAACAGGTGTTTCAGATGCCAGATTGGTC
AGATCTTTTTGCTGATCTAACGGCTCCTTTACACCTCGATATTGGTTGTGCGCGGGGGCGGTTTATTTTAGAGATGGCCC
AACGGTTTCCAGAGCGTAATTTTGTTGGGGTAGAAATTCGCGAACCCCTCGTGGACGATGCCAACGAAATCCGGGATCAA
CTGGGGCTAAAAAATCTTCACTACGTTTTTGCGAATATTAATACCTCTCTCCAGGTGCTGTTGGACTCCTTGCCGACGGA
AACTTTGACTTGGATCACGATTCAATTTCCTGATCCTTGGTTTAAGAAAAAGCACCACAAACGCCGGGTTGTGCAACCAG
ATCTAGTTGACATTCTGGCGAAACATACACCCCAAAAGCTGGTTTTGTTTTGTCAGTCGGATGTTGAAGAAGTTGCTTTA
GAAATGAGAGAAAAATTTCTGGAGCATGAAAAATTTGTCCTCGCCCATGATTCGTTTTGGCTAAAGGAGAATATTTTTCC
AGTGCCGACGGAGCGGGAAGTCGCCACGGCCAATAAAGGCGAACCGGTCTACCGTTTTCTTTTGCATAAAAAAGAAGAAA
GTAGCGCGTAA

Upstream 100 bases:

>100_bases
TTTTGCTCTTTTTCATTTAAGCATATCCAAGTTTAGCGTGGGGGACGTGGCACAATGGGATGGCAAATTTTTTCGTTGGA
CATTTCTAAGGAGTGAGTTC

Downstream 100 bases:

>100_bases
CAGATGCCTTGGCGATCGCCCCTAAAGCGCCTAAATACCTTGGCCAAGCCCTAGCCCACTAACACAAATGATCTCGTCTG
AAGCCGAACCGTTGATTTCG

Product: tRNA (guanine-N(7)-)-methyltransferase

Products: NA

Alternate protein names: tRNA(m7G46)-methyltransferase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGRSRVRQHVNPLTDKYQQVFQMPDWSDLFADLTAPLHLDIGCARGRFILEMAQRFPERNFVGVEIREPLVDDANEIRDQ
LGLKNLHYVFANINTSLQVLLDSLPTETLTWITIQFPDPWFKKKHHKRRVVQPDLVDILAKHTPQKLVLFCQSDVEEVAL
EMREKFLEHEKFVLAHDSFWLKENIFPVPTEREVATANKGEPVYRFLLHKKEESSA

Sequences:

>Translated_216_residues
MGRSRVRQHVNPLTDKYQQVFQMPDWSDLFADLTAPLHLDIGCARGRFILEMAQRFPERNFVGVEIREPLVDDANEIRDQ
LGLKNLHYVFANINTSLQVLLDSLPTETLTWITIQFPDPWFKKKHHKRRVVQPDLVDILAKHTPQKLVLFCQSDVEEVAL
EMREKFLEHEKFVLAHDSFWLKENIFPVPTEREVATANKGEPVYRFLLHKKEESSA
>Mature_215_residues
GRSRVRQHVNPLTDKYQQVFQMPDWSDLFADLTAPLHLDIGCARGRFILEMAQRFPERNFVGVEIREPLVDDANEIRDQL
GLKNLHYVFANINTSLQVLLDSLPTETLTWITIQFPDPWFKKKHHKRRVVQPDLVDILAKHTPQKLVLFCQSDVEEVALE
MREKFLEHEKFVLAHDSFWLKENIFPVPTEREVATANKGEPVYRFLLHKKEESSA

Specific function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA [H]

COG id: COG0220

COG function: function code R; Predicted S-adenosylmethionine-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmB family [H]

Homologues:

Organism=Escherichia coli, GI1789330, Length=172, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17536689, Length=179, Percent_Identity=26.2569832402235, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320000, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003358 [H]

Pfam domain/function: PF02390 Methyltransf_4 [H]

EC number: =2.1.1.33 [H]

Molecular weight: Translated: 25314; Mature: 25183

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRSRVRQHVNPLTDKYQQVFQMPDWSDLFADLTAPLHLDIGCARGRFILEMAQRFPERN
CCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCC
FVGVEIREPLVDDANEIRDQLGLKNLHYVFANINTSLQVLLDSLPTETLTWITIQFPDPW
EEEEEECCCCCCCHHHHHHHHCCCHHEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCHH
FKKKHHKRRVVQPDLVDILAKHTPQKLVLFCQSDVEEVALEMREKFLEHEKFVLAHDSFW
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCEE
LKENIFPVPTEREVATANKGEPVYRFLLHKKEESSA
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GRSRVRQHVNPLTDKYQQVFQMPDWSDLFADLTAPLHLDIGCARGRFILEMAQRFPERN
CHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCC
FVGVEIREPLVDDANEIRDQLGLKNLHYVFANINTSLQVLLDSLPTETLTWITIQFPDPW
EEEEEECCCCCCCHHHHHHHHCCCHHEEEEECCCHHHHHHHHHCCCCEEEEEEEECCCHH
FKKKHHKRRVVQPDLVDILAKHTPQKLVLFCQSDVEEVALEMREKFLEHEKFVLAHDSFW
HHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCEE
LKENIFPVPTEREVATANKGEPVYRFLLHKKEESSA
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA