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The map label for this gene is moeA [H]

Identifier: 170077394

GI number: 170077394

Start: 800544

End: 801755

Strand: Reverse

Name: moeA [H]

Synonym: SYNPCC7002_A0771

Alternate gene names: 170077394

Gene position: 801755-800544 (Counterclockwise)

Preceding gene: 170077395

Following gene: 170077393

Centisome position: 26.65

GC content: 54.62

Gene sequence:

>1212_bases
ATGATTTCCGTTGATCAAGCCCAAGCTTTAATTCTCCAGGCGATCGCCCCCCTTAGTGAAACCGAACCCAGCACCCTAGA
AACGGCCCTGGGACGAATTTTAGCGACGACGGCGACCGGAAAATTGGATATTCCCCACTGGGATAATTCCGCCATGGATG
GCTATGCGATCCGGTTTGCAGACCTGACAGAGCAACCCGTTGAACTGGAGATTATTGAAACGATTCCGGCGGGTCAAGCG
CCCCAAAAATCCTTAGCGCCTGGCCAAGCCGCCCGCATTTTCACCGGGGCAATGTTACCGACTGGGGCGGATACGGTGGT
GATGCAGGAGCATACAGAGCAACGGGGCGATCGGGTCAAAATTTTACAGAATCCCTCTTTGCGGCAGTTCGTGCGCCAGC
GGGGTGACTATTACCGCGCCGGGGAACCCCTTTTAAAACCAGGGCAACGGTTGGGCGCAGCGGATTTAGCCGTTCTTGCG
GCCTGTCAATGTGTCGAATTTCCGGTCTATCGGCAACCGAGGGTCGCAATTTTTTCCACGGGGGGTGAGTTGCGATCGCC
CCGGGAAAAGTTAGAAATCGGCCAAATTGTTGATTCGAATCGCTATGGTTTGACGGCCTTTGTCCAGGGGCAACGAGCGA
TTCCGAAAAATTTTGGCATTGTCCCTGATGATCCGGCCCAACTGAAAGCAACCATGAAAAAGGCGATCGCCGCTGGGGAT
CTCATCCTCTCGACGGGAGGCGTTTCCGTGGGCGAGTTTGATTATGTTGAAAAACTCCTCGAAGAATTAGGGGGCGAAAT
TTTTATCCGTAGTGTGGCGATTCGCCCTGGTAAACCCCTGACAGTGGCGAAATTTCCTGGGAATAAACTCTACTTTGGGC
TGCCCGGCAATCCGGTATCGGCCCTGGTGGGTTGTTGGCGGTTCGTGCAACCTGCGTTGAAAAAGTTGTCCGGCAATGCT
GGGCCTTGGGCACCAGAATTTGTCTGGGCCACCTGTGATCAACCCCTCAAGGGAGCCGGAAAGCGGGATGCTTACCTGTG
GGGAACCTTGGCAACCACGGCGACGGGTTATCTTTTTCATTTAGCTGGGGGCGGCCATAGTTCTGCTAATTTAGTTAATC
TTGCCCAAACCAATGCCCTCGCCATTGTGCCCCAGGGGACTGGTGAAATCCCAGCAGGCGATCGCCTCCGGGTGATGCGT
CTCCAAACCTAG

Upstream 100 bases:

>100_bases
TACGAAGAGAATCGCCAGCCCCAAGGTGGCAGCCCAGGGCCAGACTAACTTGTTTGGCAAACTGACTTACTATATTGAGT
GTCAAAACGTGGGACGAAGT

Downstream 100 bases:

>100_bases
GAGAATTTTTGTTGAAAAGGGAAATCCCAGGCTTACTATAGGAAGATAATTCCGCAACTCAATCGGCCATCGTTGCGTCT
TTAGGGTAAATAGCCGCACC

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MISVDQAQALILQAIAPLSETEPSTLETALGRILATTATGKLDIPHWDNSAMDGYAIRFADLTEQPVELEIIETIPAGQA
PQKSLAPGQAARIFTGAMLPTGADTVVMQEHTEQRGDRVKILQNPSLRQFVRQRGDYYRAGEPLLKPGQRLGAADLAVLA
ACQCVEFPVYRQPRVAIFSTGGELRSPREKLEIGQIVDSNRYGLTAFVQGQRAIPKNFGIVPDDPAQLKATMKKAIAAGD
LILSTGGVSVGEFDYVEKLLEELGGEIFIRSVAIRPGKPLTVAKFPGNKLYFGLPGNPVSALVGCWRFVQPALKKLSGNA
GPWAPEFVWATCDQPLKGAGKRDAYLWGTLATTATGYLFHLAGGGHSSANLVNLAQTNALAIVPQGTGEIPAGDRLRVMR
LQT

Sequences:

>Translated_403_residues
MISVDQAQALILQAIAPLSETEPSTLETALGRILATTATGKLDIPHWDNSAMDGYAIRFADLTEQPVELEIIETIPAGQA
PQKSLAPGQAARIFTGAMLPTGADTVVMQEHTEQRGDRVKILQNPSLRQFVRQRGDYYRAGEPLLKPGQRLGAADLAVLA
ACQCVEFPVYRQPRVAIFSTGGELRSPREKLEIGQIVDSNRYGLTAFVQGQRAIPKNFGIVPDDPAQLKATMKKAIAAGD
LILSTGGVSVGEFDYVEKLLEELGGEIFIRSVAIRPGKPLTVAKFPGNKLYFGLPGNPVSALVGCWRFVQPALKKLSGNA
GPWAPEFVWATCDQPLKGAGKRDAYLWGTLATTATGYLFHLAGGGHSSANLVNLAQTNALAIVPQGTGEIPAGDRLRVMR
LQT
>Mature_403_residues
MISVDQAQALILQAIAPLSETEPSTLETALGRILATTATGKLDIPHWDNSAMDGYAIRFADLTEQPVELEIIETIPAGQA
PQKSLAPGQAARIFTGAMLPTGADTVVMQEHTEQRGDRVKILQNPSLRQFVRQRGDYYRAGEPLLKPGQRLGAADLAVLA
ACQCVEFPVYRQPRVAIFSTGGELRSPREKLEIGQIVDSNRYGLTAFVQGQRAIPKNFGIVPDDPAQLKATMKKAIAAGD
LILSTGGVSVGEFDYVEKLLEELGGEIFIRSVAIRPGKPLTVAKFPGNKLYFGLPGNPVSALVGCWRFVQPALKKLSGNA
GPWAPEFVWATCDQPLKGAGKRDAYLWGTLATTATGYLFHLAGGGHSSANLVNLAQTNALAIVPQGTGEIPAGDRLRVMR
LQT

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=417, Percent_Identity=34.7721822541966, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI66932975, Length=417, Percent_Identity=34.7721822541966, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI1787049, Length=390, Percent_Identity=38.7179487179487, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI25147659, Length=305, Percent_Identity=32.1311475409836, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17562606, Length=310, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136978, Length=371, Percent_Identity=29.3800539083558, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24638841, Length=371, Percent_Identity=29.3800539083558, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 43220; Mature: 43220

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS01079 MOCF_BIOSYNTHESIS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVDQAQALILQAIAPLSETEPSTLETALGRILATTATGKLDIPHWDNSAMDGYAIRFA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEE
DLTEQPVELEIIETIPAGQAPQKSLAPGQAARIFTGAMLPTGADTVVMQEHTEQRGDRVK
CCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCCCEEEEEHHHHHCCCEEE
ILQNPSLRQFVRQRGDYYRAGEPLLKPGQRLGAADLAVLAACQCVEFPVYRQPRVAIFST
EECCCCHHHHHHHCCCEECCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEC
GGELRSPREKLEIGQIVDSNRYGLTAFVQGQRAIPKNFGIVPDDPAQLKATMKKAIAAGD
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LILSTGGVSVGEFDYVEKLLEELGGEIFIRSVAIRPGKPLTVAKFPGNKLYFGLPGNPVS
EEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCCEEEEECCCCHHH
ALVGCWRFVQPALKKLSGNAGPWAPEFVWATCDQPLKGAGKRDAYLWGTLATTATGYLFH
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHCCCCCCCCEEEEEHHHHHCCEEEE
LAGGGHSSANLVNLAQTNALAIVPQGTGEIPAGDRLRVMRLQT
EECCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MISVDQAQALILQAIAPLSETEPSTLETALGRILATTATGKLDIPHWDNSAMDGYAIRFA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEE
DLTEQPVELEIIETIPAGQAPQKSLAPGQAARIFTGAMLPTGADTVVMQEHTEQRGDRVK
CCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHEECCCCCCCCCEEEEEHHHHHCCCEEE
ILQNPSLRQFVRQRGDYYRAGEPLLKPGQRLGAADLAVLAACQCVEFPVYRQPRVAIFST
EECCCCHHHHHHHCCCEECCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEC
GGELRSPREKLEIGQIVDSNRYGLTAFVQGQRAIPKNFGIVPDDPAQLKATMKKAIAAGD
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LILSTGGVSVGEFDYVEKLLEELGGEIFIRSVAIRPGKPLTVAKFPGNKLYFGLPGNPVS
EEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCCEEEEECCCCHHH
ALVGCWRFVQPALKKLSGNAGPWAPEFVWATCDQPLKGAGKRDAYLWGTLATTATGYLFH
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHCCCCCCCCEEEEEHHHHHCCEEEE
LAGGGHSSANLVNLAQTNALAIVPQGTGEIPAGDRLRVMRLQT
EECCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682795; 11759840 [H]