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The map label for this gene is grxC [H]

Identifier: 170026346

GI number: 170026346

Start: 4571109

End: 4571357

Strand: Reverse

Name: grxC [H]

Synonym: YPK_4139

Alternate gene names: 170026346

Gene position: 4571357-4571109 (Counterclockwise)

Preceding gene: 170026347

Following gene: 170026345

Centisome position: 97.48

GC content: 51.41

Gene sequence:

>249_bases
ATGGCGAAGATTGAGATGTATACCAAAGCAACATGCCCGTTCTGTCACCGTGCTAAAGCACTGCTGAACGCCAAGGGTGC
TGCTTTCCATGAAATCGCAATAGATAATGATCCGGCCAAACGCGAAGAGATGATTGCTCGTAGTGGGCGGACGACGGTGC
CTCAGATATTTATTGATGGGCAGCATATCGGTGGCTGTGATGATTTACACGCCCTGGATGCGCGCGGTGGGCTAGACCCA
CTGCTTTAA

Upstream 100 bases:

>100_bases
CTATTATATCGATATTCCGTATATCGGTATTTAGTTGTATAAGTGTTTGTTATAAAAACTCGCTATATCAATAGATTGTA
AATTTAACTGAGGTGTATCC

Downstream 100 bases:

>100_bases
CTCGTCAGTGGGCCCCGATATTAATGGGAAAAGCCCACGACGGAAGAGCTGTTTAATAAGGACGTCTAACTAAGGGTATC
TATACACATGTCAGAACAAA

Product: glutaredoxin 3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAKIEMYTKATCPFCHRAKALLNAKGAAFHEIAIDNDPAKREEMIARSGRTTVPQIFIDGQHIGGCDDLHALDARGGLDP
LL

Sequences:

>Translated_82_residues
MAKIEMYTKATCPFCHRAKALLNAKGAAFHEIAIDNDPAKREEMIARSGRTTVPQIFIDGQHIGGCDDLHALDARGGLDP
LL
>Mature_81_residues
AKIEMYTKATCPFCHRAKALLNAKGAAFHEIAIDNDPAKREEMIARSGRTTVPQIFIDGQHIGGCDDLHALDARGGLDPL
L

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=78.0487804878049, Blast_Score=142, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 8918; Mature: 8787

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIEMYTKATCPFCHRAKALLNAKGAAFHEIAIDNDPAKREEMIARSGRTTVPQIFIDG
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEEECC
QHIGGCDDLHALDARGGLDPLL
CCCCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure 
AKIEMYTKATCPFCHRAKALLNAKGAAFHEIAIDNDPAKREEMIARSGRTTVPQIFIDG
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCEEEECC
QHIGGCDDLHALDARGGLDPLL
CCCCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]