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The map label for this gene is hdfR

Identifier: 170026274

GI number: 170026274

Start: 4483642

End: 4484523

Strand: Direct

Name: hdfR

Synonym: YPK_4064

Alternate gene names: 170026274

Gene position: 4483642-4484523 (Clockwise)

Preceding gene: 170026272

Following gene: 170026281

Centisome position: 95.61

GC content: 47.62

Gene sequence:

>882_bases
GTGGATACCGAATTACTGAAAACCTTTTTAGAGGTCAGTAGAACTCGTCACTTTGGTCGCGCAGCTGAATCTCTGTACTT
AACACAGTCGGCGGTAAGTTTCCGTATCCGTCAGTTGGAAAATCAATTAGGTGCAAACTTATTCACTCGGCATCGTAATA
ATATTCGTCTCACTCCTGCGGGTGAACGGCTGGTTCCGTACGCAGAAATGCTGCTGAACACTTGGCGATTAGCCAAAAAA
GAAGTCATACATTCGCTACAACACACTGAGTTATCCATAGGTGCAACCGCATCCCTTTGGGAGGCGTACCTCACTCCATG
GTTGCAACAGTTATATGAACAACAAGAGGAACTGCGCCTTGAAGCACGCATTGCGCTGAGAAACTCACTGGTGAAGCAGT
TGCACGAACGGCAACTGGACTTGTTGATCACGACAGAACCGCCCAAAATGGATGAACTGGCCTGCCTGCTATTAGGCCAT
TTTTCACTGCGGCTTTATTCGTCGTTCTCCCTTGATTTACCAAAAGAAGATGACACCCCGAACGAGCATAAAAATGCAAG
TGAAGTGCCTTATATCAAACTTGAATGGGGGGCTGATTTCCATCAGCAGGAAAACCGTTTACTTGATAGTGAGCAGGCGC
CAATCCTCACAACGACCTCTGCCCATTTAACCCGCCAGTTGCTTGAAACGACTGGCGGTTGCGCTTTTCTGCCTGAACAT
TGGCAAAAAGAATACCCACAGCTTGTCATTCATCCTGACATTCCACCGATCGTGCGGCCACTGTATGCCGTTTGGCTACA
AAACAGTGACCAGCAAGCATTGATCAGACAACTCTTAAAAACCCCCATGAATAACGCGACCCAGAGCGTTACACGGGAGT
AA

Upstream 100 bases:

>100_bases
TCTCATGGTCGTGCTGTTTATGGCGCGGAGTATTAGATAGGCTTGACAGCGTGTAAAACAAAACATTTAAATCCTAACGA
TAAAAAAAATTGGAGATGGT

Downstream 100 bases:

>100_bases
GTGGCGATGACTGAGGGCGTGATCTGCGGTTGAGATAAAAAGCGCTCATCGCTTTCTGAATCACGATAAAGCTAAAGAGC
AAAATACCAATCACAATTTT

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKK
EVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGH
FSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEH
WQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE

Sequences:

>Translated_293_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKK
EVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGH
FSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEH
WQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
>Mature_293_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKK
EVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGH
FSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEH
WQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI48994962, Length=283, Percent_Identity=61.4840989399293, Blast_Score=340, Evalue=9e-95,
Organism=Escherichia coli, GI2367136, Length=181, Percent_Identity=32.0441988950276, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788626, Length=149, Percent_Identity=31.5436241610738, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=230, Percent_Identity=28.695652173913, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=147, Percent_Identity=31.2925170068027, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=142, Percent_Identity=26.056338028169, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDFR_YERP3 (A7FD20)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399148.1
- ProteinModelPortal:   A7FD20
- STRING:   A7FD20
- GeneID:   5385551
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0150
- eggNOG:   COG0583
- HOGENOM:   HBG536341
- OMA:   LHVGLPG
- ProtClustDB:   PRK03601
- BioCyc:   YPSE349747:YPSIP31758_0150-MONOMER
- HAMAP:   MF_01233
- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33933; Mature: 33933

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEECCC
GERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTP
HHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEH
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCEECCHH
WQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
HHHHCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEECCC
GERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTP
HHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEH
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCEECCHH
WQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
HHHHCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA