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The map label for this gene is ppiC [H]

Identifier: 170026250

GI number: 170026250

Start: 4457205

End: 4457501

Strand: Direct

Name: ppiC [H]

Synonym: YPK_4040

Alternate gene names: 170026250

Gene position: 4457205-4457501 (Clockwise)

Preceding gene: 170026249

Following gene: 170026251

Centisome position: 95.05

GC content: 44.78

Gene sequence:

>297_bases
ATGGTGACTGTTACTATGGCAAACAAAGCTTCTGCACTGCATATTCTGGTTGATGATGAAAAGCAGGCAAATGACATTCT
GGCCCAGTTGAATAACGGGGCTAATTTCCAGGAGTTAGCGAAAAAGTTCTCTAACTGCCCGTCAAAACGCAACGGTGGCG
ATCTGGGTGAGTTCAATAAAGGGGATATGGTCCCTGCATTCGATAAAGCGGTATTTAGCTGCGAATTGCTGCAACCTTAT
GGCCCGGTCAAAACTCAGTTTGGATATCACATCATTAAAGTGTTGTACCGCAGCTAA

Upstream 100 bases:

>100_bases
AATACGCACGCAGCGGCAACCAAAATACGTTACACTGACGCGCTCCGCGAGCCTATCGAAGAGACTCTGCGTAAAATAAC
CCTGTCGTTAAAATAATCTG

Downstream 100 bases:

>100_bases
TCCTGAAATACGCCACGCTATAAAAGGTGGCGTATTTCATGTTTATACTCGTCATACTTCAAACTCCATGTGCATTAGCT
GCTATCAATAACTCGAATCA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MVTVTMANKASALHILVDDEKQANDILAQLNNGANFQELAKKFSNCPSKRNGGDLGEFNKGDMVPAFDKAVFSCELLQPY
GPVKTQFGYHIIKVLYRS

Sequences:

>Translated_98_residues
MVTVTMANKASALHILVDDEKQANDILAQLNNGANFQELAKKFSNCPSKRNGGDLGEFNKGDMVPAFDKAVFSCELLQPY
GPVKTQFGYHIIKVLYRS
>Mature_98_residues
MVTVTMANKASALHILVDDEKQANDILAQLNNGANFQELAKKFSNCPSKRNGGDLGEFNKGDMVPAFDKAVFSCELLQPY
GPVKTQFGYHIIKVLYRS

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=93, Percent_Identity=67.741935483871, Blast_Score=135, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 10823; Mature: 10823

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVTMANKASALHILVDDEKQANDILAQLNNGANFQELAKKFSNCPSKRNGGDLGEFNK
CEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
GDMVPAFDKAVFSCELLQPYGPVKTQFGYHIIKVLYRS
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTVTMANKASALHILVDDEKQANDILAQLNNGANFQELAKKFSNCPSKRNGGDLGEFNK
CEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
GDMVPAFDKAVFSCELLQPYGPVKTQFGYHIIKVLYRS
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]