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The map label for this gene is rhtC [H]

Identifier: 170026208

GI number: 170026208

Start: 4408561

End: 4409181

Strand: Reverse

Name: rhtC [H]

Synonym: YPK_3997

Alternate gene names: 170026208

Gene position: 4409181-4408561 (Counterclockwise)

Preceding gene: 170026209

Following gene: 170026206

Centisome position: 94.02

GC content: 51.21

Gene sequence:

>621_bases
ATGTTGATGCTATTTCTCACCGTTGCGTTTATTCATCTGGTTGCTCTGATTAGTCCAGGGCCTGACTTCTTTTTTGTATC
GCAAACTGCCGCCAGCCGCTCACGTGGTGAGGCGATGATGGGCGTGCTGGGGATCTCGCTAGGAATTGTTATTTGGGCTG
GGGTAGCACTGATGGGGTTGAATCTCATCTTGCAGAAAATGGCTTGGCTGCATCAAATTATTATGGTCGGCGGTGGGATG
TATCTGTGTTGGATGGGGTGGCAGCTATTGAAATCGGCCCGTGCTAAACATGATGTCGCCGAAGAAGAGGTACAGGTCGT
CTTGCCTGCCCGTGGCCGCACGTTTATCCGTGGTCTGCTGACCAACCTGTCGAACCCAAAAGCCGTTATCTATTTCGGTA
GTGTATTCTCATGGTTTGTCGGTGATGACATGGGTGCAGGTGCGCGCTGGGGGTTGTTTATCCTGATTGTTGGCGAAACC
TTCTTATGGTTCACCGTGGTGGCCTGCGTATTTGCGTTACCTACCATGCGCCGTGGTTATCAGCGGCTTTCCAAGTGGAT
TGATGGGCTGGCAGGTGTGTTATTTGCCGGTTTTGGTATCCAACTGATATTGTCCCGCTAA

Upstream 100 bases:

>100_bases
CGGGTTAGCCGTTGGTGCTACCCGATGATCCTATCAACGATAAAAATCGAATTGCGTGTTAGCATAATTTTTCGATCTTC
CCTGTTATGAGTGGCTATCT

Downstream 100 bases:

>100_bases
CGGGTTAGCCAACGGGGTATTTAACCCGGTTGGCTAGCCTGACAGGCTCTTTATACTTTGCGCGCTGTGGCTAATAATGC
ACCAATCAACATAAATAGGC

Product: threonine efflux system

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMLFLTVAFIHLVALISPGPDFFFVSQTAASRSRGEAMMGVLGISLGIVIWAGVALMGLNLILQKMAWLHQIIMVGGGM
YLCWMGWQLLKSARAKHDVAEEEVQVVLPARGRTFIRGLLTNLSNPKAVIYFGSVFSWFVGDDMGAGARWGLFILIVGET
FLWFTVVACVFALPTMRRGYQRLSKWIDGLAGVLFAGFGIQLILSR

Sequences:

>Translated_206_residues
MLMLFLTVAFIHLVALISPGPDFFFVSQTAASRSRGEAMMGVLGISLGIVIWAGVALMGLNLILQKMAWLHQIIMVGGGM
YLCWMGWQLLKSARAKHDVAEEEVQVVLPARGRTFIRGLLTNLSNPKAVIYFGSVFSWFVGDDMGAGARWGLFILIVGET
FLWFTVVACVFALPTMRRGYQRLSKWIDGLAGVLFAGFGIQLILSR
>Mature_206_residues
MLMLFLTVAFIHLVALISPGPDFFFVSQTAASRSRGEAMMGVLGISLGIVIWAGVALMGLNLILQKMAWLHQIIMVGGGM
YLCWMGWQLLKSARAKHDVAEEEVQVVLPARGRTFIRGLLTNLSNPKAVIYFGSVFSWFVGDDMGAGARWGLFILIVGET
FLWFTVVACVFALPTMRRGYQRLSKWIDGLAGVLFAGFGIQLILSR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=70.873786407767, Blast_Score=306, Evalue=5e-85,
Organism=Escherichia coli, GI1786522, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788099, Length=190, Percent_Identity=25.7894736842105, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22706; Mature: 22706

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLFLTVAFIHLVALISPGPDFFFVSQTAASRSRGEAMMGVLGISLGIVIWAGVALMGL
CHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLILQKMAWLHQIIMVGGGMYLCWMGWQLLKSARAKHDVAEEEVQVVLPARGRTFIRGLL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHHHHHH
TNLSNPKAVIYFGSVFSWFVGDDMGAGARWGLFILIVGETFLWFTVVACVFALPTMRRGY
HCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSKWIDGLAGVLFAGFGIQLILSR
HHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLMLFLTVAFIHLVALISPGPDFFFVSQTAASRSRGEAMMGVLGISLGIVIWAGVALMGL
CHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLILQKMAWLHQIIMVGGGMYLCWMGWQLLKSARAKHDVAEEEVQVVLPARGRTFIRGLL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHHHHHH
TNLSNPKAVIYFGSVFSWFVGDDMGAGARWGLFILIVGETFLWFTVVACVFALPTMRRGY
HCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHH
QRLSKWIDGLAGVLFAGFGIQLILSR
HHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]