| Definition | Yersinia pseudotuberculosis YPIII chromosome, complete genome. |
|---|---|
| Accession | NC_010465 |
| Length | 4,689,441 |
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The map label for this gene is metE [H]
Identifier: 170026163
GI number: 170026163
Start: 4359721
End: 4362012
Strand: Reverse
Name: metE [H]
Synonym: YPK_3952
Alternate gene names: 170026163
Gene position: 4362012-4359721 (Counterclockwise)
Preceding gene: 170026165
Following gene: 170026161
Centisome position: 93.02
GC content: 49.78
Gene sequence:
>2292_bases ATGGGGAATAAGACGATGACAATTTTAAATCACACACTGGGTTTTCCGCGTGTTGGTCTGAAACGTGAACTGAAGAAAGC ACAAGAAAGTTACTGGGCAGGCAACTCAACACAGGAAGAATTGCTCAATGTGGGGCGTGAATTGCGTGCTCGCCATTGGC AACAGCAACAACAAGCGGGCGTTGATTTAGTGCCAGTAGGTGATTTCGCTTGGTATGACCATGTCCTGACAACCAGCCTG TTGCTGGGTAACGTTCCAGAGCGCCACCAAAATGCTGATGGCTCGATTGATATAGACACGTTGTTCCGTATTGGTCGTGG CCGTGCTCCAACCGGTAAGCCCGCAGCGGCTGCCGAGATGACTAAATGGTTTAATACCAACTATCACTACATGGTGCCTG AGTTCCAGCAAGGCCAGCAGTTTAAACTGGGTTGGACTCAACTGCTGGATGAAGTGGACGAAGCGCTGGCCTTGGGCCAC AAAATTAAACCTGTGCTGCTTGGCCCGATCACTTATCTTTGGTTGGGTAAAGTCAAAGGTGAGCAGTTCGATCGCCTCTC GCTACTGAACGATATTTTGCCGGTTTACCAGCAGGTGTTGGCTGAATTAGCGAAGCGGGGAATCGAGTGGGTGCAGATTG ATGAGCCAGCATTGGTTCTGGAATTACCACAAGAGTGGTTGGATGCCTATCAACCGGCTTATCAGGCCCTGCAAGGTCAG GTCAAATTATTGCTGACAACTTACTTCGACAGTATCGGCCATAACATCGACACTATCCGCGCTCTGCCAGTGCAAGGCTT GCATGTTGATGTGGTTGCGGGTCATGACGATCTTGCTGTTTTGAATAAAAATTTACCAAAAGAGTGGTTGTTATCTCTGG GGGTCATTAATGGCCGTAACGTATGGCGTGCTGACCTGAGTAGTTGGTTTGAACGTCTGCAGCCATTGGTTAATAGCCGC CCGCTGTGGTTGGGTAGCTCATGCTCCTTATTGCACAGCCCGATTGATTTAAATGAAGAGACCCGTCTTGATGCAGAAGT GAAGAGCTGGTTTGCCTTCGCCCTGCAAAAATGTGCTGAGTTAGCGCTGCTAACACAAGCATTGAATGCACCTAATGACG CTAAGCTGGCAGAACTGGCTGCGTACAGTGCGCCGATCCGCGCCCGTCGTTCCTCCAGCCGCGTGCATAATGCGCAAGTT GAGCAGCGTTTAGCTGCGATTACTTCGCAGGATATTGAGCGCCAACTGCCTTATGAAGCACGTGCTGAAACTCAGCGTAA GCGTTTTAATTTGCCTGCCTGGCCAACCACGACCATTGGTTCTTTCCCACAAACGACAGAGATCCGTGGTTTACGCCTTG ATTTTAAACAAGGTCGTCTGGACGGTAAAAACTATCGCACAGGGATCAGCGAGCATATCAAACAAGCTATTGCTGAACAG GAACGCTTGGGCCTGGACGTGCTGGTTCACGGTGAAGCAGAACGTAACGACATGGTCGAATACTTCGGCGAACACTTGGA TGGTTTTGTCTTTACACAAAATGGTTGGGTACAGAGCTACGGTTCCCGCTGTGTGAAACCGCCGGTCATCATTGGTGATA TTAGCCGCCCAGAAGCGATTACTGTTGAGTGGGCGAAATATGCTCAATCCTTAACAGAGAAACCGGTAAAAGGCATGCTT ACCGGCCCGGTCACTATTCTGTGCTGGTCGTTCCCGCGTGAAGATGTCAGCCGTGAGACGATTGCCAAACAAATTGCGCT GGCTTTGCGTGACGAAGTGGAAGATTTAGAAAAAGCAGGCATTGGTATCATCCAGATTGATGAACCTGCATTACGTGAAG GTTTGCCTCTGCGCCGTGCTGACTGGCAAGCCTATCTGCAATGGGCCGTCGACGCCTTTAAATTGAATGCCGCTGTGGCG CAAAACGATACACAGATCCATACCCACATGTGTTATTGCGAGTTCAATGACATCATGGATTCCATTGCCGCACTGGATGC TGATGTGATTACCATCGAAACCTCCCGCTCAGATATGGAACTGTTGGAATCATTTGAAGACTTCGCTTATCCGAATGAAA TTGGTCCCGGTGTTTATGATATTCATTCACCGAATGTGCCAAGTGTTGAATGGATTGAAGCGTTATTACGCAAAGCCGCT CAACGTATTCCGGCCGAGCGTTTGTGGGTGAACCCAGATTGTGGTTTGAAAACCCGCGGCTGGCCTGAGACGCGTCAGGC TCTGGCGAATATGGTGCTGGCAGCGCAGCGTCTGCGTGAAGAACAGATTTAA
Upstream 100 bases:
>100_bases GTTCGATCATGAGAGTCCTTCACAGTGACTGTGAAAAAAATGCGCTTGTGGAATATACAGTACCTGCGGATTATAGATGT GTAAACATCTGGATGGCTAA
Downstream 100 bases:
>100_bases TTAAACCGTTTTACTCTGTGTAGTGGGGCTTTTGGGGCGCTTTCGCGCCCTTTTTTATTGCGTTTCTTCTGGAATGGGGA TGGCCGAGACACCATGTTGG
Product: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase
Products: NA
Alternate protein names: Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme [H]
Number of amino acids: Translated: 763; Mature: 762
Protein sequence:
>763_residues MGNKTMTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDFAWYDHVLTTSL LLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGH KIKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQ VKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVAGHDDLAVLNKNLPKEWLLSLGVINGRNVWRADLSSWFERLQPLVNSR PLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQV EQRLAAITSQDIERQLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKQAIAEQ ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAITVEWAKYAQSLTEKPVKGML TGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVA QNDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAA QRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQI
Sequences:
>Translated_763_residues MGNKTMTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDFAWYDHVLTTSL LLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGH KIKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQ VKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVAGHDDLAVLNKNLPKEWLLSLGVINGRNVWRADLSSWFERLQPLVNSR PLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQV EQRLAAITSQDIERQLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKQAIAEQ ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAITVEWAKYAQSLTEKPVKGML TGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVA QNDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAA QRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQI >Mature_762_residues GNKTMTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDFAWYDHVLTTSLL LGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHK IKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQV KLLLTTYFDSIGHNIDTIRALPVQGLHVDVVAGHDDLAVLNKNLPKEWLLSLGVINGRNVWRADLSSWFERLQPLVNSRP LWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVE QRLAAITSQDIERQLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKQAIAEQE RLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAITVEWAKYAQSLTEKPVKGMLT GPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQ NDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAAQ RIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQI
Specific function: Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation [H]
COG id: COG0620
COG function: function code E; Methionine synthase II (cobalamin-independent)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the vitamin-B12 independent methionine synthase family [H]
Homologues:
Organism=Escherichia coli, GI2367304, Length=754, Percent_Identity=85.1458885941645, Blast_Score=1332, Evalue=0.0, Organism=Saccharomyces cerevisiae, GI6320936, Length=769, Percent_Identity=47.9843953185956, Blast_Score=709, Evalue=0.0,
Paralogues:
None
Copy number: 45,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013215 - InterPro: IPR006276 - InterPro: IPR002629 [H]
Pfam domain/function: PF08267 Meth_synt_1; PF01717 Meth_synt_2 [H]
EC number: =2.1.1.14 [H]
Molecular weight: Translated: 86185; Mature: 86054
Theoretical pI: Translated: 5.30; Mature: 5.30
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGNKTMTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAG CCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC VDLVPVGDFAWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEM CEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCCCCEEHHHHHHHCCCCCCCCCCHHHHHH TKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGKVKG HHHHCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCC EQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQ CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH VKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVAGHDDLAVLNKNLPKEWLLSLGVINGRN HHHHHHHHHHHHCCCCHHEEECCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHCCCCCCC VWRADLSSWFERLQPLVNSRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAE HHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH LALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIERQLPYEA HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH RAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKQAIAEQ HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCHHHCCHHHHHHHHHHHH ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAI HHCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCCEEEECCCCCCEE TVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAG EEHHHHHHHHHHHCCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC IGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCEFNDIMD CCEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHH SIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAA HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH QRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQI HHCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure GNKTMTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAG CCCEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC VDLVPVGDFAWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEM CEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCCCCEEHHHHHHHCCCCCCCCCCHHHHHH TKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGKVKG HHHHCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCC EQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQ CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHH VKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVAGHDDLAVLNKNLPKEWLLSLGVINGRN HHHHHHHHHHHHCCCCHHEEECCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHCCCCCCC VWRADLSSWFERLQPLVNSRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAE HHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH LALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIERQLPYEA HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH RAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKQAIAEQ HHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCCCHHHCCHHHHHHHHHHHH ERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAI HHCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCCEEEECCCCCCEE TVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAG EEHHHHHHHHHHHCCCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC IGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCEFNDIMD CCEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEHHHHHH SIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAA HHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH QRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQI HHCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA