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The map label for this gene is hmuT

Identifier: 170026104

GI number: 170026104

Start: 4292067

End: 4292906

Strand: Direct

Name: hmuT

Synonym: YPK_3891

Alternate gene names: 170026104

Gene position: 4292067-4292906 (Clockwise)

Preceding gene: 170026103

Following gene: 170026105

Centisome position: 91.53

GC content: 53.45

Gene sequence:

>840_bases
ATGAGACTCCGGTTGCTGTCGCTCCCCTTCATTCTGTCGCTCTGTGCCCCTCTGCTGCCACTAAATACCTTGGCGGCAGA
ACGTATTGTGACTATTGGTGGAGATGTAACAGAAATTGCCTATGCACTCGGTGCAGGTGATGAGATTGTGGCCCGTGACA
GCACCAGTCAACAGCCTCAGGCAGCGCAAAAGCTGCCTGATGTTGGTTATATGCGCACGCTGAACGCGGAAGGTATTTTG
GCGATGAAGCCAACCATGTTGCTGGTTAGTGAACTGGCTCAGCCCTCACTGGTGCTGACGCAGATCGCCAGCAGCGGTGT
GAATGTAGTGACGGTACCAGGCCAGACGACACCTGAAAGCGTCGCGATGAAGATTAATGCCGTTGCCACGGCACTTCATC
AGACGGAGAAAGGGCAGAAACTGATCGAAGACTACCAACAGCGCTTGGCCGCCGTGAACAAGACTCCACTGCCAGTGAAA
GTGCTGTTTGTCATGAGCCATGGCGGGTTAACACCGATGGCTGCGGGCCAAAATACGGCGGCAGATGCCATGATCCGTGC
GGCGGGTGGCAGTAATGCGATGCAGGGCTTTAGCCGTTATCGCCCGCTGTCGCAGGAAGGGGTTATCGCCAGTGCGCCAG
ATTTATTATTGATCACCACGGATGGCGTTAAAGCGCTGGGTAGCAGTGAAAATATCTGGAAATTACCGGGTATGGCACTG
ACTCCGGCTGGCAAACATAAACGCCTGTTGGTCGTGGATGATATGGCATTACTTGGCTTTGGTCTGGAAACACCACAAGT
GCTTGCACAGCTACGTGAAAAAATGGAACAGATGCAATGA

Upstream 100 bases:

>100_bases
CTCAACTTGCCCAACTCTACGGCCAGCGCACCGAAGGGCAGCCAGAACAAAACCAATGGCGTGAACAGATTGCCCGCCTA
ATCAACAAGGATATCGCCGC

Downstream 100 bases:

>100_bases
ATGGTCGTGTTCAGCCACGACTGATGCTGGGCTTCTTACTGATATTGCTAGTCATTCTGGCGCTGGGCTCAGCTAATATG
GGGGCCTTATCGCTCTCATT

Product: periplasmic binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQAAQKLPDVGYMRTLNAEGIL
AMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPESVAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVK
VLFVMSHGGLTPMAAGQNTAADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMAL
TPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ

Sequences:

>Translated_279_residues
MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQAAQKLPDVGYMRTLNAEGIL
AMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPESVAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVK
VLFVMSHGGLTPMAAGQNTAADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMAL
TPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ
>Mature_279_residues
MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQAAQKLPDVGYMRTLNAEGIL
AMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPESVAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVK
VLFVMSHGGLTPMAAGQNTAADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMAL
TPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ

Specific function: Part of the binding-protein-dependent transport system for hemin

COG id: COG4558

COG function: function code P; ABC-type hemin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain

Homologues:

Organism=Escherichia coli, GI1786353, Length=240, Percent_Identity=29.5833333333333, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMUT_YERPE (Q56991)

Other databases:

- EMBL:   U60647
- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AE0035
- PIR:   T12071
- RefSeq:   NP_667878.1
- RefSeq:   NP_991830.1
- RefSeq:   YP_002345363.1
- PDB:   3MD9
- PDBsum:   3MD9
- ProteinModelPortal:   Q56991
- SMR:   Q56991
- IntAct:   Q56991
- GeneID:   1145488
- GeneID:   1173127
- GeneID:   2766946
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO0281
- KEGG:   ypk:y0541
- KEGG:   ypm:YP_0436
- HOGENOM:   HBG708630
- OMA:   VGYMRAL
- ProtClustDB:   CLSK888441
- BioCyc:   YPES187410:Y0541-MONOMER
- BioCyc:   YPES214092:YPO0281-MONOMER
- InterPro:   IPR002491

Pfam domain/function: PF01497 Peripla_BP_2

EC number: NA

Molecular weight: Translated: 29574; Mature: 29574

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQ
CCEEEEHHHHHHHHHHHHCCHHHHHHHHEEECCCCHHHHHHHHCCCCCEEECCCCCCCCH
AAQKLPDVGYMRTLNAEGILAMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPES
HHHHCCCCCCEEEECCCCEEEECHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHH
VAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVKVLFVMSHGGLTPMAAGQNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHH
ADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMAL
HHHHEEECCCCHHHHHHHHCCCCCCCCEEECCCCEEEEECCCHHHCCCCCCEEECCCEEE
TPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ
CCCCCCCEEEEEECHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQ
CCEEEEHHHHHHHHHHHHCCHHHHHHHHEEECCCCHHHHHHHHCCCCCEEECCCCCCCCH
AAQKLPDVGYMRTLNAEGILAMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPES
HHHHCCCCCCEEEECCCCEEEECHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCHHH
VAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVKVLFVMSHGGLTPMAAGQNTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHH
ADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMAL
HHHHEEECCCCHHHHHHHHCCCCCCCCEEECCCCEEEEECCCHHHCCCCCCEEECCCEEE
TPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ
CCCCCCCEEEEEECHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430