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The map label for this gene is yrhP [H]

Identifier: 170025796

GI number: 170025796

Start: 3943905

End: 3944573

Strand: Direct

Name: yrhP [H]

Synonym: YPK_3581

Alternate gene names: 170025796

Gene position: 3943905-3944573 (Clockwise)

Preceding gene: 170025790

Following gene: 170025805

Centisome position: 84.1

GC content: 48.13

Gene sequence:

>669_bases
ATGCTAAGTGGCGTTATTATCGCCAGATTGCTTCGCTCCCATTCGGTAATTAAGATGCTTGAAACCTCGTTATTCGTCGC
GACACTCGCGACATTGGGAATGATCTCCCCCGGACCTGATTTTTTTCTGGTGATCAAAAACGCTGCCCGCTATCGCCGCA
CTGCCGCCATGATGACGGCACTTGGTGTAATTTTGGGTGTTGCAACGCATATGTCTTACTGCGTGGCCGGTCTGGCGGTC
GTTATCACGACTACACCATGGTTATTCAATTTGCTGAAATATGCCGGGGCCTGCTACCTGATCTGGATTGGTATTCAAGC
ACTGCTGTCACGGGGAGAAAGTAAGTTTAGTATTGATAATACTGCACAGTATCCCATCTCGCTCAAAGCCGCATTTTTGC
AAGGTTACCTCTGCAACTTATTGAATCCAAAAGCAACTCTTTTCTTCCTCGCCGTTTTCACGCAAATATTGCAGATAAAC
TCCGGCATAGGAGAAAAACTCTGGTATGCCTCAATCATCTGGATACTGTCCGCAATCTGGTGGCCTGTGCTGGTGATCCT
GATCCAAAGCGCGCCAGTACGCCGTGGTTTAGCCAAAACACAAAAAGTGGTCGATAAAGTGTTAGGCGGCCTGTTGATCG
GCCTTGGCATCAAAGTCGCATTAGGCTAA

Upstream 100 bases:

>100_bases
TTTTCCGCTCGCGGCGCTGTAGCGTCAGGTCAGAAAGACTAAATCCCATCACTGTTCACAACAAAATGGCATCAGATAAC
CAATAAGAGTAATGCAAAGA

Downstream 100 bases:

>100_bases
CACCGCTATCAACCCCAGCATCTCGGTTAAGTATTTCGCTACTGAGATGGCCATCTACAATGACCGTTTACTATCCACAA
TAGTGTTGGCGATAACATTG

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLSGVIIARLLRSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAV
VITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQIN
SGIGEKLWYASIIWILSAIWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Sequences:

>Translated_222_residues
MLSGVIIARLLRSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAV
VITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQIN
SGIGEKLWYASIIWILSAIWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
>Mature_222_residues
MLSGVIIARLLRSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTALGVILGVATHMSYCVAGLAV
VITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQIN
SGIGEKLWYASIIWILSAIWWPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786522, Length=199, Percent_Identity=30.1507537688442, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788099, Length=184, Percent_Identity=33.1521739130435, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24142; Mature: 24142

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGVIIARLLRSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHH
LGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDN
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSAIW
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSGVIIARLLRSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMMTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHH
LGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDN
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TAQYPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQINSGIGEKLWYASIIWILSAIW
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WPVLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]