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The map label for this gene is aroF [H]

Identifier: 170025572

GI number: 170025572

Start: 3682832

End: 3683908

Strand: Reverse

Name: aroF [H]

Synonym: YPK_3357

Alternate gene names: 170025572

Gene position: 3683908-3682832 (Counterclockwise)

Preceding gene: 170025576

Following gene: 170025571

Centisome position: 78.56

GC content: 48.93

Gene sequence:

>1077_bases
ATGATCATGCAAAAAGACTCGCTCAATAACGTCCATATCAGTGCCGAACAAATCCTGATAACCCCGGAAGAACTGAAAAA
TCAGTTTCCACTGAGCGAAAATGATCAGTATTCGATAGAGCGCGCACGTAAAACCATTGCTGACATTATTCAGGGGCGAG
ATCCGCGTCTGTTGGTCGTTTGTGGGCCCTGTTCAATTCATGATGTGGATGCGGCACTGGATTACGCGCGTCGTTTGAAA
AAACTCTCTGTGGAATTGGATGACAGCTTATATATCGTTATGCGTGTCTATTTTGAGAAGCCAAGAACTACCGTGGGTTG
GAAAGGCCTGATCAATGACCCTGCAATGGATGGTTCATTTGATGTAGAGGCAGGTTTACACATTGCCCGTCGTTTATTGC
TGGATTTAGTGGGCATGGGGTTGCCGTTAGCGACTGAAGCTCTGGATCCTAATAGCCCACAATATTTAGGTGACCTGTTC
AGTTGGTCGGCCATTGGTGCCCGTACAACGGAGTCACAGACCCACCGTGAAATGGCATCAGGCTTGTCTATGCCGGTTGG
ATTTAAAAATGGCACTGACGGTAGCCTAGGCACGGCAATCAATGCAATGCGCGCCGCTGCCATGCCACATCGCTTTATGG
GGATCAATCAGTCGGGCCAGGTCTGCCTGTTACAAACTCAGGGTAACCCACACGGCCATGTCATTCTACGGGGAGGTAAA
ACACCAAACTACAGTGCACAAGATGTCGCTCAGTGTGAAAAACAGATGCAGGATGCGGGACTCATCCCATCCTTAATGAT
AGATTGCAGTCACGGTAATTCAAATAAAGACTACCGCCGTCAGGTTGCGGTGGCTGAATCTGTGGTTGAACAGATCAAGG
CGGGCAATCGTTCAATTACAGGTGTGATGCTGGAAAGCCACATCCACGAAGGAAATCAGTCATCTGAACAGCCACGTGCT
GATATGCGCTACGGTGTTTCTGTGACTGACGCCTGTATTAACTGGGAAAGCACTGAAACCCTGTTACGTGGTATGCGCCA
AGAATTGCTTGCAGCACTGACGGCACGGACTGCATGA

Upstream 100 bases:

>100_bases
TTACACATATGGATTGAAAACTTTACATCACATGGTATTGTGGAGCTCTCAAACGATAAATACGCCAGCGACATCCGCTA
AACAGAGATAGGTAAAGATT

Downstream 100 bases:

>100_bases
GGAAAAGTAAGTATGGTGGCTGAACTGACTGCTTTACGCGATCAAATTGATGAAGTCGATAAAGCGTTGTTGGATTTGCT
GGCTAAACGCCTGCATTTGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MIMQKDSLNNVHISAEQILITPEELKNQFPLSENDQYSIERARKTIADIIQGRDPRLLVVCGPCSIHDVDAALDYARRLK
KLSVELDDSLYIVMRVYFEKPRTTVGWKGLINDPAMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLF
SWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFMGINQSGQVCLLQTQGNPHGHVILRGGK
TPNYSAQDVAQCEKQMQDAGLIPSLMIDCSHGNSNKDYRRQVAVAESVVEQIKAGNRSITGVMLESHIHEGNQSSEQPRA
DMRYGVSVTDACINWESTETLLRGMRQELLAALTARTA

Sequences:

>Translated_358_residues
MIMQKDSLNNVHISAEQILITPEELKNQFPLSENDQYSIERARKTIADIIQGRDPRLLVVCGPCSIHDVDAALDYARRLK
KLSVELDDSLYIVMRVYFEKPRTTVGWKGLINDPAMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLF
SWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFMGINQSGQVCLLQTQGNPHGHVILRGGK
TPNYSAQDVAQCEKQMQDAGLIPSLMIDCSHGNSNKDYRRQVAVAESVVEQIKAGNRSITGVMLESHIHEGNQSSEQPRA
DMRYGVSVTDACINWESTETLLRGMRQELLAALTARTA
>Mature_358_residues
MIMQKDSLNNVHISAEQILITPEELKNQFPLSENDQYSIERARKTIADIIQGRDPRLLVVCGPCSIHDVDAALDYARRLK
KLSVELDDSLYIVMRVYFEKPRTTVGWKGLINDPAMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLF
SWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFMGINQSGQVCLLQTQGNPHGHVILRGGK
TPNYSAQDVAQCEKQMQDAGLIPSLMIDCSHGNSNKDYRRQVAVAESVVEQIKAGNRSITGVMLESHIHEGNQSSEQPRA
DMRYGVSVTDACINWESTETLLRGMRQELLAALTARTA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=356, Percent_Identity=79.7752808988764, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=54.8850574712644, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1787996, Length=344, Percent_Identity=48.546511627907, Blast_Score=342, Evalue=3e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=53.2951289398281, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320240, Length=351, Percent_Identity=51.2820512820513, Blast_Score=352, Evalue=4e-98,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39317; Mature: 39317

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMQKDSLNNVHISAEQILITPEELKNQFPLSENDQYSIERARKTIADIIQGRDPRLLVV
CCCCCCCCCCEEEECCEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
CGPCSIHDVDAALDYARRLKKLSVELDDSLYIVMRVYFEKPRTTVGWKGLINDPAMDGSF
ECCCCCCHHHHHHHHHHHHHHHCEECCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCC
DVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMAS
CHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFMGINQSGQVCLLQTQGNPHGHVILRGGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCEEEEECCC
TPNYSAQDVAQCEKQMQDAGLIPSLMIDCSHGNSNKDYRRQVAVAESVVEQIKAGNRSIT
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
GVMLESHIHEGNQSSEQPRADMRYGVSVTDACINWESTETLLRGMRQELLAALTARTA
HHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIMQKDSLNNVHISAEQILITPEELKNQFPLSENDQYSIERARKTIADIIQGRDPRLLVV
CCCCCCCCCCEEEECCEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
CGPCSIHDVDAALDYARRLKKLSVELDDSLYIVMRVYFEKPRTTVGWKGLINDPAMDGSF
ECCCCCCHHHHHHHHHHHHHHHCEECCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCC
DVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMAS
CHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFMGINQSGQVCLLQTQGNPHGHVILRGGK
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCCCCCEEEEECCC
TPNYSAQDVAQCEKQMQDAGLIPSLMIDCSHGNSNKDYRRQVAVAESVVEQIKAGNRSIT
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
GVMLESHIHEGNQSSEQPRADMRYGVSVTDACINWESTETLLRGMRQELLAALTARTA
HHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]