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The map label for this gene is dinB

Identifier: 170025513

GI number: 170025513

Start: 3609473

End: 3610531

Strand: Reverse

Name: dinB

Synonym: YPK_3296

Alternate gene names: 170025513

Gene position: 3610531-3609473 (Counterclockwise)

Preceding gene: 170025515

Following gene: 170025511

Centisome position: 76.99

GC content: 49.58

Gene sequence:

>1059_bases
ATGCGAAAAATTATTCATGTCGATATGGATTGCTTCTTCGCGGCAGTAGAAATGCGCGACGACCCTCGCCTGCGTGATAT
CCCCCTTGCGATTGGTGGCAGTAAGGAGCGGCGTGGCGTGATCAGTACCGCTAATTATCCCGCTCGGCGTTATGGTGTTC
GCAGCGCTATGCCAACGGCGATGGCGTTTAAACTCTGCCCACAGTTAACATTGCTGCCTGGTAGAATGGCGGCTTATAAA
GAGGCCTCGCAGCATATTCGCGAAATTTTTGCCCGTTATACCCCATTGATTGAACCACTGTCATTGGATGAGGCCTATTT
GGATGTTTCTGATAGCTTGGCGTGCGGTGGCTCTGCAACATTAATAGCTCAAGAGATCCGCCAGTCTATCGCTAGTGAGC
TGAACCTGACAGCCTCCGCGGGGATTGCCCCGATAAAATTTCTTGCCAAAATCGCCTCAGAGCTGAATAAACCCAATGGC
CAGTATGTGATTACACCGAATCAGATCCAGCCCTTCCTACAGGATTTACCGCTGAGTAAAATTCCCGGTGTTGGTGCCGT
CACCGCCAAACGTTTACAGGCGCTGGGGTTGGTAACCTGTGGCGAGATACAAAAGTATCCGTTGGCAGAATTGTTAAAAC
ATTTTGGTAAGTTTGGCCGCGTATTGTGGGAGCGTAGTCACGGTATTGATGAACGTGAAATATCCCCAGATCGTCTACGT
AAATCCGTTGGTGTGGAGAAAACACTGGCCGAGGATATTTATGACTGGGAAAGTTGTGAGGCGTTGATCGAAGAACTTTA
TCTTGAACTGGAAACTCGTTTACGTAAGGTAAAGCCGGACCTACACATTGCCCGGCAGGGCGTTAAGCTAAAATTTCATG
ATTTTCAGCAGACCACGCAAGAACACACATGGCCAGTATTGAATAAAGCAGATTTACTGCAAATTGCCCACGCCGCATGG
AATGAACGGCGGGCCGAGCGGGGAGTCCGTTTGGTCGGGCTGCATGTTACGTTGCTGGATCCACAACTTGAGCGGCAATT
ATTGCTTGATTGGGGCTAG

Upstream 100 bases:

>100_bases
CCTTGCATGAACTCATCGGTACGACTATAGATTAGGATAATCTTGAATCCTTTTACTTTAACTGTATACTTATACAGTTG
TTTGTTGGGCGGGGGATTTC

Downstream 100 bases:

>100_bases
CTATCGCACGGTGTAAATAACACCCACTTGCCCGAATCACTGGTGTGTGTCAGTTCATCGGGCTTGGCTTGTAACGGTAA
TTATTTTGGCTATTAAAGCC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQEHTWPVLNKADLLQIAHAAW
NERRAERGVRLVGLHVTLLDPQLERQLLLDWG

Sequences:

>Translated_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQEHTWPVLNKADLLQIAHAAW
NERRAERGVRLVGLHVTLLDPQLERQLLLDWG
>Mature_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQEHTWPVLNKADLLQIAHAAW
NERRAERGVRLVGLHVTLLDPQLERQLLLDWG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7705344, Length=383, Percent_Identity=34.2036553524804, Blast_Score=178, Evalue=8e-45,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=29.6296296296296, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=29.8461538461538, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=33.8645418326693, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI5729982, Length=120, Percent_Identity=40, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=76.5042979942693, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1787432, Length=219, Percent_Identity=25.1141552511416, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193205700, Length=312, Percent_Identity=34.9358974358974, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=31.2741312741313, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=257, Percent_Identity=28.0155642023346, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534089, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=209, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=29.8780487804878, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355641, Length=357, Percent_Identity=30.2521008403361, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644984, Length=357, Percent_Identity=30.2521008403361, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668444, Length=120, Percent_Identity=35.8333333333333, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_YERP3 (A7FLI9)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402117.1
- ProteinModelPortal:   A7FLI9
- SMR:   A7FLI9
- STRING:   A7FLI9
- GeneID:   5386187
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3157
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   VICAASY
- ProtClustDB:   PRK02406
- BioCyc:   YPSE349747:YPSIP31758_3157-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 39647; Mature: 39647

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKADLLQIAHAAWNERRAERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKADLLQIAHAAWNERRAERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA