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The map label for this gene is htpG [H]

Identifier: 170025412

GI number: 170025412

Start: 3494311

End: 3496185

Strand: Reverse

Name: htpG [H]

Synonym: YPK_3195

Alternate gene names: 170025412

Gene position: 3496185-3494311 (Counterclockwise)

Preceding gene: 170025413

Following gene: 170025411

Centisome position: 74.55

GC content: 46.35

Gene sequence:

>1875_bases
ATGAATATGAAAGGTCAAGAAACCCGTGGATTCCAGTCTGAAGTAAAACAGCTCCTCCATTTGATGATTCACTCGCTTTA
TTCCAATAAAGAAATTTTTCTGCGCGAGCTGATCTCCAATGCTTCTGATGCTGCAGATAAACTCCGTTTCCGTGCCCTGT
CTAACCCCGAACTCTTTGAAGGGGATGGCGAACTGAGAGTGCGTTTATCTTTTGATAAAGAGAAACGTACTTTAACCCTG
AGTGATAACGGCATCGGTATGACCCGTGACGAAGTCATTGATAATCTTGGTACTATCGCCAAATCAGGGACTAAAGCATT
TCTTGAATCAATCGGTTCTGATCAGGCCAAAGACAGCCAATTAATCGGTCAATTTGGTGTGGGTTTCTACTCAGCATTTA
TTGTTGCCGATAAAGTTACCGTACGTACCCGAGCTGCCGGTGCCCCTGCCGATACCGGTGTATTCTGGGAATCTGCTGGT
GAAGGTGATTACACCATCGCCGATATAACTAAAGACGAGCGTGGTACTGAAATTACGCTACATTTGCGTGAAGGCGAAGA
CGAGTATCTGGATGACTGGCGTCTACGTTCTGTTATCAGCAAATACTCAGATCATATTGCACTGCCGGTTGAAATTCAGG
TTAAAAATGAAGAAGACGGCACTGTCACCTGGGAAAAAATCAACAAAGCTCAGGCGCTGTGGACCCGTGGTAAAGCAGAA
ATCTCTGACGACGAATACAAAGCATTTTACAAACATATTGCCCATGATTTTACCGATCCACTCAGTTGGAGTCACAACCG
CGTTGAAGGGAAGCAGGAATACACCAGCTTGCTGTATATCCCCGCGCAGGCACCATGGGATATGTGGAACCGTGATCACA
AACATGGTTTAAAACTTTATGTGCAGCGTGTGTTTATCATGGATGAAGCTGAGCAGTTTATGCCGAACTATCTGCGGTTT
GTCCGTGGTTTGATAGATTCGAACGATCTGCCGCTGAACGTCTCCCGTGAGATTTTACAAGACAGTCGTATTACACAGAA
TCTGCGCAGTGCATTGACTAAGCGTGTGCTGCAAATGCTGGAAAAACTGGCTAAAGATGATGCTGAGAAATATCAGCAAT
TCTGGCAACAATTCGGCATGGCATTAAAAGAAGGCCCAGCGGAAGATGGTAGCAATAAAGAGACTATCGCTAAGCTATTG
CGCTTTGCTTCAACGCATACCGACAGTTCCGCACAGACCGTGTCACTGGAAGACTATGTCAGCCGTATGGCAGAAGGGCA
GGAGAAAATTTATTACATCACTGCTGACAGCTATGCTGCTGCGAAGAGTAGCCCGCATCTGGAACTGTTCCGTAAAAAAG
GTATCGAGGTCCTATTGTTATCCGATCGTATCGACGAATGGATGATGAGCTACCTGACTGAGTTCGAAGGTAAAGCGTTC
CAATCGGTCAGTAAAGCAGATGACTCACTGAATAAATTGGCTGATGAAGAAAATCCAGAGCAGCAAGAAGCAGAGAAAGC
ACTGGAGCCCTTCGTTGAACGCGTGAAAACGTTATTGGGTGAGCGTGTTAAAGACGTGCGCTTGACACATCGCCTAACGG
ATACACCCGCAATCGTAACGACTGATGCGGATGAAATGAGTACGCAGATGGCTAAGCTATTCGCGGCCGCGGGTCAACAG
GCTCCGGAAGTGAAGTACATCTTTGAACTGAACCCAGATCATGGCTTGGTTAAGCGTGCTGCGGAAGTTACAGATGACAC
TCAATTTGCACAATGGGTTGAGTTATTACTGGATCAGGCGCTGCTCGCGGAGAGGGGAACATTGGAAGACCCTAACCAGT
TTATTCGTCGAATGAATCAGTTACTCACGGCTTAA

Upstream 100 bases:

>100_bases
GTTTTTTCTGCTTTACCGCTTGAAACTGCCGCTATTGGCCCCATTTGATCTTCATTGTTCGATTTTATCTGCCTGTTGGT
AATTTGGATTGAGGTAATTA

Downstream 100 bases:

>100_bases
TCGATAAAAAAACACCCTTGTTCAACGTATTGCCAAGGGTGTTTTTTATTGTACCTCTCTGATTTAAATCTATATTTTAT
TATTTCATTTCCTCAAATAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTL
SDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAG
EGDYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAE
ISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRF
VRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLL
RFASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAF
QSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQ
APEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA

Sequences:

>Translated_624_residues
MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTL
SDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAG
EGDYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAE
ISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRF
VRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLL
RFASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAF
QSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQ
APEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA
>Mature_624_residues
MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTL
SDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAG
EGDYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAE
ISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRF
VRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLL
RFASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAF
QSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQ
APEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=36.8575624082232, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=680, Percent_Identity=37.3529411764706, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=36.3492063492063, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=412, Percent_Identity=35.6796116504854, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI153792590, Length=409, Percent_Identity=35.9413202933985, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=86.3782051282051, Blast_Score=1130, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=667, Percent_Identity=36.8815592203898, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=678, Percent_Identity=37.7581120943953, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=636, Percent_Identity=34.4339622641509, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI115535167, Length=429, Percent_Identity=37.7622377622378, Blast_Score=279, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=38.4388807069219, Blast_Score=461, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=685, Percent_Identity=37.8102189781022, Blast_Score=459, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=37.370753323486, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24586016, Length=634, Percent_Identity=36.2776025236593, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17647529, Length=411, Percent_Identity=35.2798053527981, Blast_Score=265, Evalue=6e-71,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71032; Mature: 71032

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEC
GDGELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQ
CCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHH
LIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITL
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEE
HLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAE
EEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCC
ISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLY
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCCCHHHCCCCHHHHHHHH
VQRVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQML
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYV
HHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHH
SRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAF
HHHHCCCCEEEEEEECCHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCHHH
QSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TDADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQA
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLAERGTLEDPNQFIRRMNQLLTA
HHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEC
GDGELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQ
CCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHH
LIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITL
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCCCCEEEE
HLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAE
EEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCC
ISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLY
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEECCCCCHHHCCCCHHHHHHHH
VQRVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQML
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYV
HHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHH
SRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAF
HHHHCCCCEEEEEEECCHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCHHH
QSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
TDADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQA
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLAERGTLEDPNQFIRRMNQLLTA
HHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA