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The map label for this gene is galE [H]

Identifier: 170025165

GI number: 170025165

Start: 3241069

End: 3242085

Strand: Direct

Name: galE [H]

Synonym: YPK_2943

Alternate gene names: 170025165

Gene position: 3241069-3242085 (Clockwise)

Preceding gene: 170025164

Following gene: 170025166

Centisome position: 69.11

GC content: 52.41

Gene sequence:

>1017_bases
ATGTACGTTCTGGTAACAGGTGGTAGCGGTTACATTGGTAGCCATACCTGTGTGCAATTGATTGAGGCTGGCTACAAACC
CGTCATCCTCGACAACCTCTGCAACAGTAAATCCAGCGTATTAGCCCGGATACACAGTTTGACCGGCTATACGCCTGAAC
TTTATGCGGGTGATATCCGTGATCGCACACTGCTCGATAGCATTTTTGCGGCTCATCCTATTCATGCCGTCATTCATTTT
GCCGGTCTGAAAGCGGTTGGCGAATCCGTCAACCGGCCACTCGAGTATTACAACAACAACGTGTTTGGCACCTTGGTGTT
ATTAGAAGCGATGCGCGCCGCACAGGTTAAGAACCTGATTTTCAGCTCCTCAGCCACTGTTTATGGCGATCAGCCACAGA
TTCCCTATGTAGAAAGCTTCCCGACCGGTTCACCGTCCAGCCCCTATGGCCGCAGTAAATTGATGGTTGAGCAAATTCTG
CAAGATGTTCAACTGGCTGATCCACAGTGGAATATGACGATTTTGCGCTATTTCAACCCCGTCGGTGCGCACCCATCGGG
TTTGATGGGCGAAGATCCGCAAGGTATCCCGAATAATTTAATGCCGTTTATTGCTCAAGTCGCCGTTGGCCGCCGTGAAT
CACTGGCCATCTTTGGCAATGACTACCCAACCCCTGATGGTACTGGCGTCCGTGACTATATCCATGTGGTGGATCTGGCT
GACGGCCATGTGGCCGCAATGAAAACCTTACACGGCAAGCCCGGCGTGCATATCTTCAATCTGGGGGCCGGTGTCGGCCA
CAGTGTGTTGCAAGTGGTGGCCGCATTCAGTAAAGCCTGTGGTAAACCACTGGCCTACCATTTTGCCCCGCGCCGCGAAG
GGGATCTGCCTGCCTACTGGGCTGATGCAACTAAAGCGGCGGAACAACTAGGCTGGCGAGTCAGCCGCTCACTTGATGAG
ATGGCGGCAGATACTTGGCACTGGCAATCAAAAAATCCTCAAGGCTACCCCGATTAA

Upstream 100 bases:

>100_bases
AAATTGAGTGTAAACGATTCCATTATTGAGCGTAGATCACCTTTTTACCCATAATGGCGTGCTATCTTTATTGCATTGAA
CTCATTAGAGGAGTCTTATT

Downstream 100 bases:

>100_bases
GGCAATTTTATGACGCATTTTAACCCTGTGGATCATCCACATCGTCGCTATAACCCGTTGAAAGACCAGTGGGTATTGGT
CTCGCCTCATCGGGCTAAAC

Product: UDP-galactose-4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIRDRTLLDSIFAAHPIHAVIHF
AGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLIFSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQIL
QDVQLADPQWNMTILRYFNPVGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNDYPTPDGTGVRDYIHVVDLA
DGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYWADATKAAEQLGWRVSRSLDE
MAADTWHWQSKNPQGYPD

Sequences:

>Translated_338_residues
MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIRDRTLLDSIFAAHPIHAVIHF
AGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLIFSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQIL
QDVQLADPQWNMTILRYFNPVGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNDYPTPDGTGVRDYIHVVDLA
DGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYWADATKAAEQLGWRVSRSLDE
MAADTWHWQSKNPQGYPD
>Mature_338_residues
MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIRDRTLLDSIFAAHPIHAVIHF
AGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLIFSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQIL
QDVQLADPQWNMTILRYFNPVGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNDYPTPDGTGVRDYIHVVDLA
DGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYWADATKAAEQLGWRVSRSLDE
MAADTWHWQSKNPQGYPD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=55.5882352941177, Blast_Score=397, Evalue=1e-111,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=55.5882352941177, Blast_Score=397, Evalue=1e-111,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=55.5882352941177, Blast_Score=397, Evalue=1e-111,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=31.2727272727273, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI42516563, Length=334, Percent_Identity=23.6526946107784, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=76.3313609467456, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=27.445652173913, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI48994969, Length=355, Percent_Identity=27.887323943662, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=48.4057971014493, Blast_Score=345, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.1268011527378, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17568069, Length=333, Percent_Identity=24.9249249249249, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=51.3119533527697, Blast_Score=343, Evalue=2e-95,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=54.0697674418605, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36790; Mature: 36790

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIR
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCC
DRTLLDSIFAAHPIHAVIHFAGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
FSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQILQDVQLADPQWNMTILRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHEEECCC
VGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNDYPTPDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHEEEEECC
DGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYW
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCH
ADATKAAEQLGWRVSRSLDEMAADTWHWQSKNPQGYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIR
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCC
DRTLLDSIFAAHPIHAVIHFAGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
FSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQILQDVQLADPQWNMTILRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHEEECCC
VGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNDYPTPDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHEEEEECC
DGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYW
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCH
ADATKAAEQLGWRVSRSLDEMAADTWHWQSKNPQGYPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]