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The map label for this gene is betI [H]

Identifier: 170025137

GI number: 170025137

Start: 3213130

End: 3213672

Strand: Direct

Name: betI [H]

Synonym: YPK_2915

Alternate gene names: 170025137

Gene position: 3213130-3213672 (Clockwise)

Preceding gene: 170025134

Following gene: 170025138

Centisome position: 68.52

GC content: 49.54

Gene sequence:

>543_bases
ATGGCCGCGGTGAATGAAGTGGGAATGCATGAAGCGTCTATTGCGCAGATTGCAAAGCGTGCTGGCGTATCCAACGGCAT
TATCAGCCACTATTTCCGTGACAAAAATGGCCTGCTAGAAGCCACAATGAGGTATCTGATAAGGCACCTTGGCGAGGCGG
TGAAGCAGCACTTGGCTGTCCTGTCCGTCAACGATCCTCGTGCCCGTTTGCGGGCGATCGCCGAAGGCAACTTTGATGAC
AGCCAGATCAATAGCGCCGCGATGAAAACCTGGCTGGCATTTTGGGCAAGCAGTATGCATAGCCCACAATTGTATCGGTT
ACAGCAGGTGAATAACCGCCGACTCTATTCAAATTTATGTGCTGAATTCAAACGTTGTTTACCGCGAGAGCAAGCGCAGC
TCGCCGCTAAAGGTATGGCGGGTTTGATTGATGGATTATGGCTACGCAGTGCATTGAGTGGCGAACACTTTAACCGTCAG
GAAGCGCTGCTGATTATCCATAACTATATTGAGCAGCAATTGAACATTAAATATAAGTGCTGA

Upstream 100 bases:

>100_bases
CATGAATAACAGTATTAATTGATTGAATTTAAAGGAGTCCAGACCCGTGCCAAAAGTAGGAATGCAGCCGATCCGACGGC
AGCAATTGATAGAGGCAACA

Downstream 100 bases:

>100_bases
ACAAAATTCGAACGCACTGAACGGTATTTAGCCGTACAGGAAAAGACAGGAGAGACTATGTCCCGCTACGGCTTGCAAAA
ACTTTATATCAACGGCGCGT

Product: transcriptional regulator BetI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAVLSVNDPRARLRAIAEGNFDD
SQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQ
EALLIIHNYIEQQLNIKYKC

Sequences:

>Translated_180_residues
MAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAVLSVNDPRARLRAIAEGNFDD
SQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQ
EALLIIHNYIEQQLNIKYKC
>Mature_179_residues
AAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAVLSVNDPRARLRAIAEGNFDDS
QINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQE
ALLIIHNYIEQQLNIKYKC

Specific function: Repressor involved in choline regulation of the bet genes [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786505, Length=174, Percent_Identity=62.6436781609195, Blast_Score=224, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR017757
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 20378; Mature: 20247

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAV
CCCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLC
HCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
AEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAV
CCCHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLC
HCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
AEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA