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The map label for this gene is katA [H]

Identifier: 170025079

GI number: 170025079

Start: 3147393

End: 3148832

Strand: Direct

Name: katA [H]

Synonym: YPK_2855

Alternate gene names: 170025079

Gene position: 3147393-3148832 (Clockwise)

Preceding gene: 170025077

Following gene: 170025081

Centisome position: 67.12

GC content: 49.38

Gene sequence:

>1440_bases
ATGAGCAAGAAGAAAGGATTAACCACCGCGGCAGGCGCTCCCGTTGTCGATAATAATAATGTTATTACGGCTGGCCGCCG
TGGCCCGATGCTACTGCAAGATGTTTGGTTCCTGGAAAAATTAGCCCATTTTGACCGTGAAGTGATCCCTGAGCGCCGCA
TGCATGCTAAAGGCTCCGGTGCATACGGTACGTTCACCGTGACTCATGATATTACCCAATATACTCGCGCAAAAATTTTC
TCAGAGATCGGTAAAAAAACAGACATGTTTGTCCGCTTCTCCACTGTGGCCGGTGAACGCGGTGCTGCAGATGCTGAACG
TGATATCCGTGGTTTTGCCATGAAGTTTTATACCGAGGAAGGCAACTGGGATTTGGTTGGTAACGATACACCGGTCTTCT
ATTTACGTGATCCACTGAAGTTCCCGGACCTGAACCACGTGGTCAAACGCGACCCTCGTACCAACCTGCGTAACCCGGTT
TATAAATGGGATTTCTTCTCTCAACTGCCAGAGGCGCTGCATCAGTTAACCATCGATTTCAGTGACCGTGGCTTGCCAAA
ATCTTACCGTCATATGCACGGTTTCGGTAGCCATACCTTTAGCCTAATCAATGCCAATAATGAACGTTTTTGGGTTAAAT
TCCATTTCCGTTGCCAGCAAGGCATTGAAAACCTGATGGACGATGAAGCCGAAAAACTGATTGGTTCTGATAGAGAAAGC
TCGCAGCGTGATCTGTATGAAGCGATTGAGCGCGGTGACTTCCCGCGTTGGAAACTACAGATTCAGGTAATGCCGGAGCA
CAAAGCATCACAAACACCTTATAACCCATTTGATCTGACTAAAGTCTGGCCGCACGGTGATTACCCGCTGATCGATGTCG
GCTACTTCGAATTGAATCGCAACCCGGAAAACTACTTCGCTGAAGTGGAACAATCCTCATTCAATCCAGCTAACGTTGTC
CCTGGGATCAGTTTCTCCCCAGACCGCATGTTACAAGGCCGCCTGTTCTCATACGGTGATGCCGCCCGCTATCGTTTAGG
GGTTAACCATCATCAGATCCCGGTGAACAGTGCTAAATGTCCGTTCCATAATTATCATCGTGACGGCGCAATGCGCGTTG
ATGGTAACAGTGGTAATGGCGCAACCTATGAGCCAAACAGCTTTGGCCTGTTCCAAGAACAGCCTGATTTCAGCGAACCG
CCACTGACATTGGAAGGGGCGGCAGATCATTGGAATCACCGCGAAGACACCGACTATTTCTCTCAACCACGGGCGCTGTT
TAACCTGCTCAGTGAAGAAGAGCATCAACGCATGTTCACCCGTATTGCGGGTGAGTTATCGCAAGTTCCTGAAGCTATCC
AACGCCGCCAGATAGCGTTGTTTACGCAGGTTGACCCGGCTTATGGCGCCGGTGTGAAAAAAGCACTTGGCCTGAATTAA

Upstream 100 bases:

>100_bases
GTTTTTGTTAAAATTATTATCTTGTCAATCACGTTTTTGACGCGATATCACGCTTAAACCCAAAACCGCAATCAATTCAA
CAGCCATACTGGAGAACATG

Downstream 100 bases:

>100_bases
ACCCGATCAGCCCCTTTGAACTGCACCCCAAATGTTGGATAACCCCCTGACATTTGGAGGTGTATTTTTATGGCTTATCC
CGTGTCTTCCTAACCCGTTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKIF
SEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPV
YKWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRES
SQRDLYEAIERGDFPRWKLQIQVMPEHKASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANVV
PGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEP
PLTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN

Sequences:

>Translated_479_residues
MSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKIF
SEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPV
YKWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRES
SQRDLYEAIERGDFPRWKLQIQVMPEHKASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANVV
PGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEP
PLTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
>Mature_478_residues
SKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKIFS
EIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPVY
KWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRESS
QRDLYEAIERGDFPRWKLQIQVMPEHKASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANVVP
GISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPP
LTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=479, Percent_Identity=53.6534446764092, Blast_Score=517, Evalue=1e-147,
Organism=Escherichia coli, GI48994891, Length=494, Percent_Identity=42.3076923076923, Blast_Score=370, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=479, Percent_Identity=52.1920668058455, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=49.6868475991649, Blast_Score=486, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=49.8947368421053, Blast_Score=485, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6320462, Length=483, Percent_Identity=44.9275362318841, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=34.7140039447732, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI17981717, Length=482, Percent_Identity=50.4149377593361, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=45.8333333333333, Blast_Score=442, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54892; Mature: 54761

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSG
CCCCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
AYGTFTVTHDITQYTRAKIFSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEE
CEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEECC
GNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPVYKWDFFSQLPEALHQLTIDF
CCEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHEEECC
SDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRES
CCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCH
SQRDLYEAIERGDFPRWKLQIQVMPEHKASQTPYNPFDLTKVWPHGDYPLIDVGYFELNR
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECC
NPENYFAEVEQSSFNPANVVPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKC
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHCCCCCHHEEECCCCCCCCCCCCCC
PFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLTLEGAADHWNHREDTDYF
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHHH
SQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHCCCHHHHHCCC
>Mature Secondary Structure 
SKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSG
CCCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
AYGTFTVTHDITQYTRAKIFSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEE
CEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEECC
GNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPVYKWDFFSQLPEALHQLTIDF
CCEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHEEECC
SDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRES
CCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCH
SQRDLYEAIERGDFPRWKLQIQVMPEHKASQTPYNPFDLTKVWPHGDYPLIDVGYFELNR
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECC
NPENYFAEVEQSSFNPANVVPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKC
CHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHCCCCCHHEEECCCCCCCCCCCCCC
PFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLTLEGAADHWNHREDTDYF
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHHH
SQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7786407; 7791219; 8901874; 12486720 [H]