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The map label for this gene is ynaJ [H]

Identifier: 170025059

GI number: 170025059

Start: 3119832

End: 3121358

Strand: Direct

Name: ynaJ [H]

Synonym: YPK_2835

Alternate gene names: 170025059

Gene position: 3119832-3121358 (Clockwise)

Preceding gene: 170025057

Following gene: 170025060

Centisome position: 66.53

GC content: 47.41

Gene sequence:

>1527_bases
ATGAGTAAACAGATTTCAACAAGGCATACGTTGGCTTACGGGAGTGCTAACTTGCTGGGCAGTGGGGCACTCGCCATTAG
TGGTGCCTGGCTGATGTACTTCTACACAACGTTTTGCGGACTTTCTGTTGTAGAAGCAGCCACTATCTTTTCAATCGCCA
GTATTATTGATGCCATCAGTAACCCGGTAATGGGTTATATCACGGATAACTTCTACAATACCCGTTTGGGCCGTATCTTC
GGGCGTCGTCGCTTCTTTATCTTACTGGGTATCCCACTCGTGTTGGTCTATCCAATGCTGTGGATGAGTGGTTTTGGTTT
CTGGTATTACCTACTGACCTATGCGCTGTTTGAATTAATTTACACCTCCATCATGGTGCCTTATGAAACACTGGCTACCG
AGATGACAACCGATTTTGCCAAACGCTCTAAACTGACAGGTTCTAAAGCAATCTTCGGCAAAGTAGCGAACTTCCTGGCC
GCTTTCATTCCAGGTCAATTCATTGCAATTTATGGCAAAGATTCCGCAACCCCCTTCTTATATACCGGTATCGCTTATGG
TCTGATTATGTGCTGCGCCATGATTTGGCTTTACAGCTCATCATGGGAGCGTCCAGCCAGTGAAGTGGTCAGGGAAACCA
CCAGTAGTTTAGGTCAGGCACTGAAAAAGCTGTGTGTTGATATGGCATCGACCTTCCATCTGCGCATTTTCCGCAAGCAT
CTGGGGATGTATCTGTTCGGTTTTGGTGCTGAATGGTTGTTCGCATCCGCATTTACCTACTTTATTATTTTTGGCTTGGG
ACAAGATGCCGCATTGGTTTCGCAGCTCAATAGCTTCAGTTCGATTATGCAGCTCATCTCCACCGCTATTTTTATTGGCA
TCTGCGTAAAAATGGGTTTCGCTCGTCCCTTCCGTATTGCTCTGCAAGTGGTGATTGTTAGCGTGATTGCCTATGCTGCA
CTGTATTTCACCGGTTGGTCTGAAACCACGACCGTTATCGTCTTATTCTGCATTACCGCTGTTTTCGGTTTAAGTACTGG
TGGGATCTACTATATTCCGTGGACGGTTTATACCTTCCTGGCCGATGTGGACGAAGTCTTGACCGGGCGTCGCCGTGAAG
GGATTTATGCTGGCGCGATGACATTCGCCGGGAAAATGGTACGTTCGATTATTGTCTTTGCCATGGGCTGGACGTTAAGC
CGCTTTGGTTTTGTTTCTGGTCAATCCAGTCAGCCAGAAATCGCTGTGCAAGCCATCGTGGGTGTCTTTGCCATAGGGGT
TATCTCACTGGCATTAGTTGCTATTTACTACACCACCCAGATGAAGCTGGATCGCAAAAATCACAGCATTTTACTGGAAG
AAATTGAGCGTATTAAAAATGGCGGTGCCATGGCAGATATCCCCGCTCATGCCAGAGCCGTCGCGGAAGAACTGACGGGG
TGGAAATATGAACAATGTTGGGGCAATAACCCCCTCGGCGTCAAAGAGTCGCCAACCGTCATACCCAAACCGGTTACTGA
AAGTTAA

Upstream 100 bases:

>100_bases
TCGTGATCTCCAACTCATTTTTATAAACGCTATACCGCTATAAAGAAAACAGTTATTCATTATAAATGAAACATTGTTTT
AATTTGAGGTGGCGGTAAAC

Downstream 100 bases:

>100_bases
TTAATTTCTGGTCGTGACCACAAACCGCACCGGTCCCGCCAGTGCGGTTTTTGCTTCTCCCTTCCCTGAACATGAATGGG
TAGATAAAATATCGGCGTTG

Product: putative transport protein

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIF
GRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLA
AFIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKH
LGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVIAYAA
LYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLS
RFGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTG
WKYEQCWGNNPLGVKESPTVIPKPVTES

Sequences:

>Translated_508_residues
MSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIF
GRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLA
AFIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKH
LGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVIAYAA
LYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLS
RFGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTG
WKYEQCWGNNPLGVKESPTVIPKPVTES
>Mature_507_residues
SKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIFG
RRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAA
FIPGQFIAIYGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHL
GMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVIAYAAL
YFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSR
FGFVSGQSSQPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGW
KYEQCWGNNPLGVKESPTVIPKPVTES

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787902, Length=476, Percent_Identity=21.6386554621849, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786466, Length=475, Percent_Identity=22.5263157894737, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082306, Length=476, Percent_Identity=23.3193277310924, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56188; Mature: 56056

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAIS
CCCCCCCCHHEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPVMGYITDNFYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELI
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSATPFL
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
YTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKH
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGF
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARPFRIALQVVIVSVIAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAVQAIV
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
GVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTG
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
WKYEQCWGNNPLGVKESPTVIPKPVTES
CCHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKQISTRHTLAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAIS
CCCCCCCHHEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPVMGYITDNFYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELI
CCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSATPFL
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
YTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKH
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMYLFGFGAEWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGF
HHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ARPFRIALQVVIVSVIAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
ADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAVQAIV
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
GVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTG
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
WKYEQCWGNNPLGVKESPTVIPKPVTES
CCHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]