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The map label for this gene is fabZ [H]

Identifier: 170024836

GI number: 170024836

Start: 2864728

End: 2865252

Strand: Reverse

Name: fabZ [H]

Synonym: YPK_2611

Alternate gene names: 170024836

Gene position: 2865252-2864728 (Counterclockwise)

Preceding gene: 170024837

Following gene: 170024835

Centisome position: 61.1

GC content: 36.76

Gene sequence:

>525_bases
ATGAAAAATACTGAATTAAATTTTTTAAAAACGAATTTTTTATTTAACCAAGATATTACTAATGAATTGAATACATCATT
TGGACAAGATATCATTAAAAAAATGATACCGCATCGTGAACCATTTTTAATGGTCGACAACGTAGAGCTGATCAATATTG
AATGCAGGTTAATAAAAGCAATAAGAAGAGTTGACGAAAAAGACCCGGTATTTGGTGGTCATTTCCCCAATGACCCTATA
TATCCAGGTGTATTGCAACAAGAAAGTATGTTTCAAACCGCGCTTATTTTAATGTATTTTCTGCTAAATGAAACGGCTAT
TCCGCCAGCAGAGGAGAATATCATCCACGCAGTGGGAACACGAGTATACGATGTCTTTCACTTGTCCGCAGTACGCCCAG
GAGAATTAATGACAATCCGTTGTTGTATTACAGAATACGACACATTTCTTGCCACCGCCATTGTTCAAATCACGGTTAAC
GATCAGATCGTAACCGTCGGAAAAGGAGAGTTTCATGTCTTCTGA

Upstream 100 bases:

>100_bases
GAGGTGTAAAACACACCTCTAAAATTAATGGGTGTTAATCCCGTGAGATATATAAGTAAAAAATCAGATACCAAACGATT
TTTATGGGCTATATTTAAAT

Downstream 100 bases:

>100_bases
TCGTATCGTTATCACTGGCGTTGCCATTAATACTCCCATTGGTGACACATTAGATCTAGTGGGCAATAATTTATTATCTG
GAAAATCAGCCATCGGCTAC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPI
YPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVN
DQIVTVGKGEFHVF

Sequences:

>Translated_174_residues
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPI
YPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVN
DQIVTVGKGEFHVF
>Mature_174_residues
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPI
YPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVN
DQIVTVGKGEFHVF

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=68, Percent_Identity=47.0588235294118, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 19934; Mature: 19934

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKA
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEHHHHHHHH
IRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGT
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
HHHHHHHHCCCCCCCEEEEEEEHHHHHHHHEEEEEEEEECCEEEEECCCCEEEC
>Mature Secondary Structure
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKA
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEHHHHHHHH
IRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGT
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
HHHHHHHHCCCCCCCEEEEEEEHHHHHHHHEEEEEEEEECCEEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]