BacMap

Definition	Yersinia pseudotuberculosis YPIII chromosome, complete genome.
Accession	NC_010465
Length	4,689,441

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The map label for this gene is fabG [H]

Identifier: 170024834

GI number: 170024834

Start: 2862716

End: 2863453

Strand: Reverse

Name: fabG [H]

Synonym: YPK_2609

Alternate gene names: 170024834

Gene position: 2863453-2862716 (Counterclockwise)

Preceding gene: 170024835

Following gene: 170024833

Centisome position: 61.06

GC content: 43.09

Gene sequence:

>738_bases
ATGAACCTTTTTATTAGCGGTGGTGCCAGTGGCATTGGACGAAGTGTGGTCATTGCTGCTTTGAGCAAAGGCTGGAATGT
TGGCTTTAGTTATCACAATAACAAGGAAGGTGCACAACAGTTGCTTGATATCGCGGTAGCGGAGTTTCCTCGGCAATTAT
GTCGTGCCTATCAACTCGACGTTATTGATAGTGGTGCAGTAGAGTACGTGGGAGACCGTCTTCTCGTCGATTTTAGTAAC
ATTGATGCGGTTGTTTGCAATGCTGGCATAGATTTACCGGGCAATTTGGTGTCGATGACCGATGAAGATTGGGCCTTGGT
ACTTAATACTAATTTAACTGGCACCTTCTATCTTATTCGTTATTTTTTGCCTCTATTTCTTGCTAATAAATATGGGCGCA
TTGTCACTCTATCTTCACTCGCTAAAGATGGGTCATCAGGACAAGCGGCTTATGCTGCATCAAAAGCTGGTTTGGTGGGG
TTAACTAAAACAACAGCGAAGGAATATGGACATTTCGGTATTACGGCCAATGTCGTTGTCCCAGGCTTAATTAATACCGA
AATTATTGGTGATGACATTAAGGGTATTAAGAATTTTTTTGCTCAATATGCGCCAGTGGGAAGGCTGGGCTCCCCCAGTG
AAGTCGCTGAGGTCATTTTATTTCTTGTTGCTAAAGAAAGTAGTTATGTAAACGGTGCGGTTTTCAATGTGACCGGTGGC
ATTGACTGGGTTTATTAA

Upstream 100 bases:

>100_bases
TCCGGAAATGTAAAAAAAGAAGTTAATATTTTTCTGAACAATTCTTTTGGCATGGGCGGTATTAACAGCGCTAGCTTATT
TAGTCGATATCATGGTTAAC

Downstream 100 bases:

>100_bases
CTTTGGGATACCTTAATGAATAGTATTGGTATTGAAAAAATCAGTATCTACCCAAGTAGTTTGGCGCTGAAATTATCTGA
ATTGGCACAAGCACGTGGTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSN
IDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVG
LTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEVILFLVAKESSYVNGAVFNVTGG
IDWVY

Sequences:

>Translated_245_residues
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSN
IDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVG
LTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEVILFLVAKESSYVNGAVFNVTGG
IDWVY
>Mature_245_residues
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSN
IDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVG
LTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEVILFLVAKESSYVNGAVFNVTGG
IDWVY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=33.739837398374, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=32.5, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI66933014, Length=191, Percent_Identity=28.7958115183246, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI19923817, Length=243, Percent_Identity=28.3950617283951, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=29.2490118577075, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=26.9076305220884, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4504505, Length=253, Percent_Identity=29.2490118577075, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=31.3131313131313, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=28.968253968254, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=27.710843373494, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4503301, Length=195, Percent_Identity=29.2307692307692, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI83715985, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20149619, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=33.8842975206612, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=31.9838056680162, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=30.2788844621514, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=30.3643724696356, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788459, Length=239, Percent_Identity=26.7782426778243, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=30.7086614173228, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=28.099173553719, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=31.0756972111554, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=25.5905511811024, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=27.8008298755187, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=27.0491803278689, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=241, Percent_Identity=26.9709543568465, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789057, Length=177, Percent_Identity=28.2485875706215, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=30.5439330543933, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=29.5833333333333, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=28.3950617283951, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=25.7028112449799, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=30.1526717557252, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=24.8995983935743, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=29.3650793650794, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=30.8510638297872, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=28.1368821292776, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=28.3524904214559, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=29.3436293436293, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=27.4368231046931, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=26.9961977186312, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=178, Percent_Identity=28.6516853932584, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=139, Percent_Identity=28.7769784172662, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=27.8388278388278, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=250, Percent_Identity=29.2, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=236, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=25.1012145748988, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=37.1900826446281, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=29.4354838709677, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=31.3953488372093, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=27.8225806451613, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859837, Length=185, Percent_Identity=30.8108108108108, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.6, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=29.4354838709677, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=28.6307053941909, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116007236, Length=212, Percent_Identity=27.8301886792453, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26118; Mature: 26118

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLD
CEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIR
CCCCCCHHHCCCEEEEEECCCCEEEEECCCCCCCCEEEECCCCEEEEEECCCCHHHHHHH
YFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVV
HHHHHHHHCCCCCEEEEHHHHCCCCCCCEEEHHCCCCEEEEEHHHHHHCCCCCEEEEEEE
PGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEVILFLVAKESSYVNGAVFNVTGG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCC
IDWVY
CEECC
>Mature Secondary Structure
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLD
CEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIR
CCCCCCHHHCCCEEEEEECCCCEEEEECCCCCCCCEEEECCCCEEEEEECCCCHHHHHHH
YFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVV
HHHHHHHHCCCCCEEEEHHHHCCCCCCCEEEHHCCCCEEEEEHHHHHHCCCCCEEEEEEE
PGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEVILFLVAKESSYVNGAVFNVTGG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCC
IDWVY
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]