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The map label for this gene is caiD [H]

Identifier: 170024832

GI number: 170024832

Start: 2860750

End: 2861469

Strand: Reverse

Name: caiD [H]

Synonym: YPK_2607

Alternate gene names: 170024832

Gene position: 2861469-2860750 (Counterclockwise)

Preceding gene: 170024833

Following gene: 170024831

Centisome position: 61.02

GC content: 39.31

Gene sequence:

>720_bases
ATGCATGAATATGTCACTGTACCTATCAAATTTAGCCCCGATTCATTAGCCGATTTCGAAAATCGCTTTATCTCTGCGCT
AAATGACGAGCGCTATAAAGTCATTGTACTTATCGGAGGGCCTACCTACTTTAGTATGGGTATGGATCTTACGTATATTT
CTACCCATTATGACGCCGACTTCGTGTCGCAATTCTGCCATATTCTAAAAATGGTAAGGAACAGCCACAAGCCCGTATTA
GCGAAGGTTGAAGGGAATGTTATCGCTGGGGGGCTTGCCTTACTGTCGGTTGTCGATTTTATTCTGTCTAGCGATAGCGC
GTCCTTTAGTTTGCCAGAAGTCACCTTTGGAATTACACCAACAATAGCCATGTCTTGCTTACTTGAACGTATTAGGCCTC
ATCATCTTAAATACTTCGTATGGAGCTCAAGTGTTATTTCGGCAAAACAAGCCCTAAAATGGGGTTTGATCGATCAGATA
AATACACTGGAAAACTTAGATCAAGATATTCAAGTTATAAGTAATAAGCTATCTCGCATTCCAAAATCCGCTATAAGAGA
AAGTAAATTACTGTTGGCTGAACAATATTCTTTCGAAGAAAGTTTGGATTTAGGTAGCCATCTTCTGGTGGAGAGACTAA
ATGATGCTCAGACCATAGAAAAAATACGTCACTACTTAGAAGACATTAAGTTATTTAATGATGAATATGCGGATGACTAA

Upstream 100 bases:

>100_bases
TTAGACGGGGACAACTTACAGGACTGGTATACACACCATTACAGCGGGAGTGGGCTCCTTATTCTTGAGCGTATCGATAA
CCACTTACGGCGTTATCGCT

Downstream 100 bases:

>100_bases
TATGAAAAAAATTTATTTAAGAAAAAGTGATGAAGGTATTGCTTTTATGCATATTAACGATCCAGTCAACAAAAATGCCA
TTGATGATGAGTTTTGTTTA

Product: enoyl-CoA hydratase/isomerase

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVL
AKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQI
NTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD

Sequences:

>Translated_239_residues
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVL
AKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQI
NTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
>Mature_239_residues
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVL
AKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQI
NTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI221142681, Length=159, Percent_Identity=30.8176100628931, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 27090; Mature: 27090

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDAD
CCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCEEEEECCCCHH
FVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITP
HHHHHHHHHHHHHCCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCH
TIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRI
HHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
CHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDAD
CCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCCEEEEECCCCHH
FVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITP
HHHHHHHHHHHHHCCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCH
TIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRI
HHHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
CHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA