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The map label for this gene is mglC [H]

Identifier: 170024789

GI number: 170024789

Start: 2814784

End: 2815794

Strand: Reverse

Name: mglC [H]

Synonym: YPK_2564

Alternate gene names: 170024789

Gene position: 2815794-2814784 (Counterclockwise)

Preceding gene: 170024790

Following gene: 170024780

Centisome position: 60.05

GC content: 44.41

Gene sequence:

>1011_bases
ATGAATGTGTTAAATAAGAAAGATATGCTCACTTACTTTAAAGAGAGCGGGATTTATGTGGTGTTGTTTGTGCTATTGGC
AATTATTATTATCAAGGATCCGACTTTTTTAAGTTTGATGAATTTAAGTAACATTCTGACTCAATCTTCGGTGCGTATTA
TTATCGCGTTAGGGGTCGCGGGTTTGATTGTTACCCAAGGCACGGATTTGTCCGCAGGTCGTCAGGTAGGGTTAGCCGCA
GTGGTCGCTGCGACAATGCTACAATCGATGGATAACGTGAATAAAGTTTTCCCGGACTTGCAGACTGTACCTATTCCAGT
GGTCATTCTCGTTGTCTGCCTGATTGGGGCGGTTATTGGTTTGATTAACGGTATAATTATTGCGTACCTGAATGTGACTC
CATTTATTACCACATTAGGCACTATGATTATCGTTTATGGCGTTAACTCGCTGTATTACGATTTTGTCGGTGCTTCACCG
ATTGCCGGTTTTGATCCTGCTTTTTCGACTTTTGCTCAAGGTTTCTTACGGTTTGGTGATTTTAAACTGTCCTATATTAC
CTTTTACGCCTTAATAGCAATTATGTTTGTATGGGTACTGTGGAATAAGACCCGTTTTGGTAAGAATATTTTTGCTATTG
GCGGCAACCCGGAGGCGGCGAAAGTCTCTGGTGTGAATGTGCCACTGAATTTGATCATGATTTATGCATTGTCGGGGGTG
TTCTATGCCTTTGGCGGTATGCTGGAAGCAGGGCGTATCGGCAGTGCGACGAACAATCTCGGATTTATGTATGAGCTAGA
TGCGATAGCGGCCTGCGTGGTGGGTGGGGTGTCCTTCAGTGGTGGCGTCGGTACCGTGATCGGCGTGGTGACCGGGGTTA
TCATCTTCACTGTCATTAACTATGGGCTCACGTATATTGGTGTGAACCCGTACTGGCAATACATTATCAAGGGCGGGATT
ATCATCTTTGCGGTTGCGTTGGATTCACTGAAGTATGCGAAGAAGAAATAG

Upstream 100 bases:

>100_bases
ACGGTCAGGTTGCGGGCATTGTTGATACCAAGCAAACCACGCAAAATGAAATATTACGCCTTGCATCCTTGCATCTCTAA
TCTAGTTGAAGGTTCTTATT

Downstream 100 bases:

>100_bases
TCGGTTGTTGTTCGTGAAAGCACGATCAGCTCTGGCGTACTGTTAGTTCAGACGTACATATATCACTATTTCAGGCATAT
CACTATTTCGTGTATATCAC

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNVLNKKDMLTYFKESGIYVVLFVLLAIIIIKDPTFLSLMNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATMLQSMDNVNKVFPDLQTVPIPVVILVVCLIGAVIGLINGIIIAYLNVTPFITTLGTMIIVYGVNSLYYDFVGASP
IAGFDPAFSTFAQGFLRFGDFKLSYITFYALIAIMFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGGI
IIFAVALDSLKYAKKK

Sequences:

>Translated_336_residues
MNVLNKKDMLTYFKESGIYVVLFVLLAIIIIKDPTFLSLMNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATMLQSMDNVNKVFPDLQTVPIPVVILVVCLIGAVIGLINGIIIAYLNVTPFITTLGTMIIVYGVNSLYYDFVGASP
IAGFDPAFSTFAQGFLRFGDFKLSYITFYALIAIMFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGGI
IIFAVALDSLKYAKKK
>Mature_336_residues
MNVLNKKDMLTYFKESGIYVVLFVLLAIIIIKDPTFLSLMNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATMLQSMDNVNKVFPDLQTVPIPVVILVVCLIGAVIGLINGIIIAYLNVTPFITTLGTMIIVYGVNSLYYDFVGASP
IAGFDPAFSTFAQGFLRFGDFKLSYITFYALIAIMFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGGI
IIFAVALDSLKYAKKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=89.2857142857143, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1790191, Length=323, Percent_Identity=34.0557275541796, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789992, Length=376, Percent_Identity=29.7872340425532, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790524, Length=326, Percent_Identity=33.1288343558282, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI145693152, Length=319, Percent_Identity=31.6614420062696, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788896, Length=334, Percent_Identity=32.6347305389222, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787794, Length=286, Percent_Identity=32.5174825174825, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87082395, Length=294, Percent_Identity=31.9727891156463, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787793, Length=305, Percent_Identity=27.8688524590164, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693214, Length=269, Percent_Identity=33.457249070632, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35978; Mature: 35978

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLNKKDMLTYFKESGIYVVLFVLLAIIIIKDPTFLSLMNLSNILTQSSVRIIIALGVA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHEEEEECHH
GLIVTQGTDLSAGRQVGLAAVVAATMLQSMDNVNKVFPDLQTVPIPVVILVVCLIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LINGIIIAYLNVTPFITTLGTMIIVYGVNSLYYDFVGASPIAGFDPAFSTFAQGFLRFGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
FKLSYITFYALIAIMFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
CHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHCCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYAKKK
CCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVLNKKDMLTYFKESGIYVVLFVLLAIIIIKDPTFLSLMNLSNILTQSSVRIIIALGVA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHEEEEECHH
GLIVTQGTDLSAGRQVGLAAVVAATMLQSMDNVNKVFPDLQTVPIPVVILVVCLIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LINGIIIAYLNVTPFITTLGTMIIVYGVNSLYYDFVGASPIAGFDPAFSTFAQGFLRFGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
FKLSYITFYALIAIMFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
CHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEEECCCCHHHHHHHHHHHHH
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVIN
HHHHCCHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYAKKK
CCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1719366; 9278503 [H]