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The map label for this gene is yfhA [H]

Identifier: 170024767

GI number: 170024767

Start: 2785927

End: 2786967

Strand: Direct

Name: yfhA [H]

Synonym: YPK_2542

Alternate gene names: 170024767

Gene position: 2785927-2786967 (Clockwise)

Preceding gene: 170024766

Following gene: 170024768

Centisome position: 59.41

GC content: 54.66

Gene sequence:

>1041_bases
ATGCATCCCGTTGATTCAGTCAGAACGCTGACGCTGGGATCTTGGGTCTTTTTAGCGCCAGCCCGCCGAACCGGGGTTTA
CCTGCTGCTGATATGGCCCATTTTATTGCTATGCCTCACCGCTGCGCTAATGCTCAGCCCCAGTGGTTTCGAAGGGGGAA
AAATGCTGGCGGTATTGGCTGGCGAAGGTAGCCAGTACGAGGAGTTTATCTTACTGCAATTGCGGTTACCAAGAGCATTG
GTTGCTCTGGGGGCCGGTGCCGCCCTGGCCATTTCCGGCGCTATTTTCCAAACCACAACCCACAACGCCTTGGCTAGCCC
CGATATTATCGGTATCACCGCCGGCGCGTCCGCTGGCGTGGTTGCCACCCTACTACTTTGGCCAGGGGTCATGCCGGTAC
CGTTGGGGGCATTTATCGGTGCCTGTACTGCAGTGGCTTTAGTCTATGCGGGCAGCATGAGCATCCTGTCTCATCCAGAG
AGAATTATTATTTCCGGTATCGCCGTTGGTGCCGTGTGCATCGCATTTGTTAACTTTGCGACTTCACAAGTCCGTCTGGA
ACAGGCGAGTCAGTTAGCCGCTTTGCTAAGCGGCAGTTTGGCAGAGAAAAACTGGCGGGATGTCGGCATCATCAGCCTGA
CATTGGGGCTGGTTATGCCGGGCTTGGTATATCTCAGCCGTCAACTCAATTACCTGAGCCTTGGAGCTGCGGTTGCCCAG
CCGCTAGGTGTCAATATCCGCCAGACGCATTGGCTAGGTCTATTGGTTGCCATCGCACTGGCAACAGCGGCGGTATTGGT
TGTCGGGCCGGTCGCCTTTATCGCCCTGTCAGCCCCCCAGATTACCCAACATCTGGTAAAGGCTAACGGCATCTCCCTGT
TATGTACCGCCTTGATGGGCGCATTTCTATTATTGGCGTCAGACATCATAACCTTGCTATTACCAACATCTTCACGGCTC
CCCGTGGGCGTTATTACGGCTGCCGTCGGGGGGATTTATCTGATGAGCTTGCTATACGCCAAAGTGAGGAAAACAAAGTG
A

Upstream 100 bases:

>100_bases
ATTATCATCGCCCCCGGCGAAGTGATGGTTGGCGTGATCACCGCTGCCGTGGGAGGGCCATTGCTTTACGCGGTGGTCAA
CAGTAAAAAAGGTATCGTCT

Downstream 100 bases:

>100_bases
GATCCCAAAGAGAGCTAACATCCCCCATGACACCATTGGAGAACCCGGGCGATATCAGTGATAAACCGCGTTTAACCACC
CAAAAACTGTCACTGGGCTA

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MHPVDSVRTLTLGSWVFLAPARRTGVYLLLIWPILLLCLTAALMLSPSGFEGGKMLAVLAGEGSQYEEFILLQLRLPRAL
VALGAGAALAISGAIFQTTTHNALASPDIIGITAGASAGVVATLLLWPGVMPVPLGAFIGACTAVALVYAGSMSILSHPE
RIIISGIAVGAVCIAFVNFATSQVRLEQASQLAALLSGSLAEKNWRDVGIISLTLGLVMPGLVYLSRQLNYLSLGAAVAQ
PLGVNIRQTHWLGLLVAIALATAAVLVVGPVAFIALSAPQITQHLVKANGISLLCTALMGAFLLLASDIITLLLPTSSRL
PVGVITAAVGGIYLMSLLYAKVRKTK

Sequences:

>Translated_346_residues
MHPVDSVRTLTLGSWVFLAPARRTGVYLLLIWPILLLCLTAALMLSPSGFEGGKMLAVLAGEGSQYEEFILLQLRLPRAL
VALGAGAALAISGAIFQTTTHNALASPDIIGITAGASAGVVATLLLWPGVMPVPLGAFIGACTAVALVYAGSMSILSHPE
RIIISGIAVGAVCIAFVNFATSQVRLEQASQLAALLSGSLAEKNWRDVGIISLTLGLVMPGLVYLSRQLNYLSLGAAVAQ
PLGVNIRQTHWLGLLVAIALATAAVLVVGPVAFIALSAPQITQHLVKANGISLLCTALMGAFLLLASDIITLLLPTSSRL
PVGVITAAVGGIYLMSLLYAKVRKTK
>Mature_346_residues
MHPVDSVRTLTLGSWVFLAPARRTGVYLLLIWPILLLCLTAALMLSPSGFEGGKMLAVLAGEGSQYEEFILLQLRLPRAL
VALGAGAALAISGAIFQTTTHNALASPDIIGITAGASAGVVATLLLWPGVMPVPLGAFIGACTAVALVYAGSMSILSHPE
RIIISGIAVGAVCIAFVNFATSQVRLEQASQLAALLSGSLAEKNWRDVGIISLTLGLVMPGLVYLSRQLNYLSLGAAVAQ
PLGVNIRQTHWLGLLVAIALATAAVLVVGPVAFIALSAPQITQHLVKANGISLLCTALMGAFLLLASDIITLLLPTSSRL
PVGVITAAVGGIYLMSLLYAKVRKTK

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=33.9285714285714, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786804, Length=298, Percent_Identity=33.2214765100671, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=313, Percent_Identity=30.0319488817891, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=32.404181184669, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786347, Length=292, Percent_Identity=29.4520547945205, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786805, Length=303, Percent_Identity=35.3135313531353, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35829; Mature: 35829

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPVDSVRTLTLGSWVFLAPARRTGVYLLLIWPILLLCLTAALMLSPSGFEGGKMLAVLA
CCCCCCHHEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GEGSQYEEFILLQLRLPRALVALGAGAALAISGAIFQTTTHNALASPDIIGITAGASAGV
CCCCCCHHEEEEEEHHHHHHHHHCCCHHHHCCCHHEEECCCCCCCCCCEEEEECCCCHHH
VATLLLWPGVMPVPLGAFIGACTAVALVYAGSMSILSHPERIIISGIAVGAVCIAFVNFA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSQVRLEQASQLAALLSGSLAEKNWRDVGIISLTLGLVMPGLVYLSRQLNYLSLGAAVAQ
HHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PLGVNIRQTHWLGLLVAIALATAAVLVVGPVAFIALSAPQITQHLVKANGISLLCTALMG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
AFLLLASDIITLLLPTSSRLPVGVITAAVGGIYLMSLLYAKVRKTK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHPVDSVRTLTLGSWVFLAPARRTGVYLLLIWPILLLCLTAALMLSPSGFEGGKMLAVLA
CCCCCCHHEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GEGSQYEEFILLQLRLPRALVALGAGAALAISGAIFQTTTHNALASPDIIGITAGASAGV
CCCCCCHHEEEEEEHHHHHHHHHCCCHHHHCCCHHEEECCCCCCCCCCEEEEECCCCHHH
VATLLLWPGVMPVPLGAFIGACTAVALVYAGSMSILSHPERIIISGIAVGAVCIAFVNFA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSQVRLEQASQLAALLSGSLAEKNWRDVGIISLTLGLVMPGLVYLSRQLNYLSLGAAVAQ
HHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
PLGVNIRQTHWLGLLVAIALATAAVLVVGPVAFIALSAPQITQHLVKANGISLLCTALMG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
AFLLLASDIITLLLPTSSRLPVGVITAAVGGIYLMSLLYAKVRKTK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]