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The map label for this gene is hmsH [H]

Identifier: 170024470

GI number: 170024470

Start: 2486293

End: 2488767

Strand: Reverse

Name: hmsH [H]

Synonym: YPK_2241

Alternate gene names: 170024470

Gene position: 2488767-2486293 (Counterclockwise)

Preceding gene: 170024471

Following gene: 170024469

Centisome position: 53.07

GC content: 48.12

Gene sequence:

>2475_bases
ATGTATAACGCATTTACAACACTACTGCGCCCGTTGCACTGGCACAGAATGACTTTATTAGCGCTATTTATTTCTGGCTT
TGTCGTTAATCCTGCTATGGCGGATACGCAGTATGACTCATTAATTATTCGTGCCAGAGCCGGTGATACTGCGCCAGTCT
TGGACTATTTACAGGAAGAATCTAAAGCGGGTCCATTGCAGAGTGGGCAGGTTGATGACTGGCTGCAAATTGCAGGTTGG
GCAGGGCGCGATCAAGAAGTGATTGATGTTTATGAACGATATCAATCTTCCATGAATATCTCTTCCAGAGGTTTGGCTTC
TGCCGCTCGAGCTTACCGCAACGAAAAGCGTTGGGATCAGGCTTTGGCCTTGTGGCAAAGCAGCTTAAAGAAAGACCCCA
CCAATCCTGATCTTATCAGCGGTATGATCATGACTCAGGCTGATGCTGGACGCGGTGGGGTTGTTTTAAAACAGGCAACA
GAGTTAGCCGAGCGTGATCCCACGGTACAAAATTACATGACGCTGTCTTATCTAAACCGGGCTACTGACCGTAATTATGA
TGCTTTGCAAGCCTCCAGCGAAGCGGTGCGATTGGCACCAACGTCTGAAGAAGTGCTCAAAAATCATCTCGAAATCTTAC
AGAGAAACCGTATTGTTGAGCCAGCGTTACGGCTTGCTAAAGAGAACCCAAATTTGGTTTCTGCTGAGCATTATCGCCAA
CTTGAGCGCGATGCTGCTGCGGAACAAGTTCGGATGGCGGTGTTGCCAACGCGCAGCGAAACCGAGCGTTTTGACATAGC
GGATAAGGCGTTAGCGGATTATCAGAATTTATTGACCCGTTGGGGCAAAGATCCAGAGGCACAGGCTGACTACCAACGCG
CACGCATTGACCGATTAGGGGCGTTATTGGTCCGTCATCAGACGGCTGATCTGATCAAAGAGTATGAAGCGATGGAGGCT
GAGGGCTATAAAATGCCTGATTATGCCCGCCGTTGGGCGGCTTCTGCCTATATTGACCGAAGGTTGCCGGAAAAAGCAGC
GCCTATCCTCTCCAGCCTCTATTATTCAGACGGTAAAACCTTCCGTAACAGCGACGATTTGCTTGATGCCGATGATCTTT
ACTATTCACTGAATGAAAGCGAACAACTTGATAAAGCCTACCAATTTGCGGTCAATTATAGCGAGCAAACGCCGTATCAG
GTTGGGGTTTATGGCCTGCCGGGCAAAGAACCGAATGATGATTGGATTGAAGGCCAAACGCTATTGGTTCAATCATTGGT
GGCATTGAATGATCTGCCCACCGCACAAAAAAAATTGGAAGATTTATCCAGTACTGCACCCGCTAATCAGAATTTAAGGA
TCGCATTAGCCAGTATTTATCTGGCCCGGGATTTACCGCGTAAAGCGGAGCAAGAATTGAAGGCCGTGGAATCATTAGCA
CCACGCAGCCTTATTCTGGAACGTGCGCAGGCTGAAACTGCGATGGCGCTACAAGAATGGCATCAGATGGAGTTACTGAC
TGATGATGTGATTAGCCGTTCCCCAGAAGATATCCCCTCTCAAGAATTAGATCGCCAACGTAAAGTCCATAACATGTATG
AACTACGGGTGAGTGGTAACCGCGTTATCTCCTCCAACAGCCCGGTGAGCGGCAATAAAGATTATGGGGTCGAAACTCTC
CTTTACAGCCCACCTATTGCAGAGAATTGGCGCGTATTTGGTGGAGGCAGTTATAACAATGGGCAGTTTGAAGAGGGGAC
GGGGATTAGCCGGATTTTGCGCTTAGGTGGTGAATGGACCTCCCGTGACCATTGGGTTGAAGGGGAAATTTCCAATCAGA
ATTATGGCAATGGCAATGGCAATAAAGTCGGGGCCCGTTTATCAACCTGGTACGACCTTAATGACCACTGGCGTGTAGGG
GGGCAGGTTGAACGTTTAGCTAAAGACACACCACTACGGGCACTGAAGAATAAAGTGACCGCGAATAGCGCGTCTGCTTA
TGTTTTCTGGAAAGCAGATGATAAGCGTGATGCTGAACTTAGCGTGACGCCGTCGCGTTTTTCTGACGGTAACAACCGTT
GGGAATATGAATTTAACGGGCGTCAGCGTATCTGGACTGGGCCTTACCTAACGGCAGATTTTAATCTGGGGTTGGCAGCC
AGCCAAAACAGTAAAGAAGATGTGATTTACTACAACCCGAAACGTGATTTTGCTTACGTTCCGGCAGTGACTCTCAATCA
CATTATGTACCGGCGGTACAAAACCATCTGGAGCCAGCAAGTCCAACTGGGTGTGGGAGGGTACTGGGAGAAAAATTACG
GTAATGGCTTGGTGACCACGGCGGGCTATGGCCAACGTGTTCAATGGAATGATGTTATCGATACCGGTGTTGCTGTGGTT
TATGACAAGCGTCCTTACGATGGTAAACGTGAGCACGATGTTACGCTTTCTTTCGATTTAAATTATCGTTTTTAA

Upstream 100 bases:

>100_bases
CTAAGAATTCCATTTCATCATCATTCCATAATGAAAAATGTACGTTCAGGAAGTCGCTTTCCTTGATCATCAAACAAGTT
GCTGGCTTAAGGGTTATATA

Downstream 100 bases:

>100_bases
GGGAATTGGACCATGGCGAAGCTATTAATTTTTATCAAATCGCTCATTGTTGGGATGATGATCGTGTCCACTATGGGGTG
TGCGGAGAAGCCAACGTTCG

Product: outer membrane protein

Products: NA

Alternate protein names: PGA export protein; Poly-beta-1,6-GlcNAc export protein [H]

Number of amino acids: Translated: 824; Mature: 824

Protein sequence:

>824_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMELLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNGNKVGARLSTWYDLNDHWRVG
GQVERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAA
SQNSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVV
YDKRPYDGKREHDVTLSFDLNYRF

Sequences:

>Translated_824_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMELLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNGNKVGARLSTWYDLNDHWRVG
GQVERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAA
SQNSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVV
YDKRPYDGKREHDVTLSFDLNYRF
>Mature_824_residues
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEESKAGPLQSGQVDDWLQIAGW
AGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQAT
ELAERDPTVQNYMTLSYLNRATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLGALLVRHQTADLIKEYEAMEA
EGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKTFRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQ
VGVYGLPGKEPNDDWIEGQTLLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
PRSLILERAQAETAMALQEWHQMELLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGNRVISSNSPVSGNKDYGVETL
LYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWTSRDHWVEGEISNQNYGNGNGNKVGARLSTWYDLNDHWRVG
GQVERLAKDTPLRALKNKVTANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAA
SQNSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTTAGYGQRVQWNDVIDTGVAVV
YDKRPYDGKREHDVTLSFDLNYRF

Specific function: Exports the biofilm adhesin polysaccharide poly-beta- 1,6-N-acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N- deacetylation of PGA by PgaB is needed for PGA export through the PgaA pori

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1787261, Length=789, Percent_Identity=41.318124207858, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 93575; Mature: 93575

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
SKAGPLQSGQVDDWLQIAGWAGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQ
HCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQATELAERDPTVQNYMTLSYLNR
HHHHHHHHHCCCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
ATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
HCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLG
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALLVRHQTADLIKEYEAMEAEGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
FRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQVGVYGLPGKEPNDDWIEGQT
CCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCHH
LLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHC
PRSLILERAQAETAMALQEWHQMELLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCC
RVISSNSPVSGNKDYGVETLLYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWT
EEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCC
SRDHWVEGEISNQNYGNGNGNKVGARLSTWYDLNDHWRVGGQVERLAKDTPLRALKNKVT
CCCCEEECEECCCCCCCCCCCEECCEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHC
ANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAA
CCCCCEEEEEECCCCCCCEEEECCHHCCCCCCEEEEEECCCEEEEECCEEEEECCCCEEE
SQNSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTT
CCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCEEEEE
AGYGQRVQWNDVIDTGVAVVYDKRPYDGKREHDVTLSFDLNYRF
CCCCCCEEEHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MYNAFTTLLRPLHWHRMTLLALFISGFVVNPAMADTQYDSLIIRARAGDTAPVLDYLQEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
SKAGPLQSGQVDDWLQIAGWAGRDQEVIDVYERYQSSMNISSRGLASAARAYRNEKRWDQ
HCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALALWQSSLKKDPTNPDLISGMIMTQADAGRGGVVLKQATELAERDPTVQNYMTLSYLNR
HHHHHHHHHCCCCCCHHHHHHHHEEECCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
ATDRNYDALQASSEAVRLAPTSEEVLKNHLEILQRNRIVEPALRLAKENPNLVSAEHYRQ
HCCCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LERDAAAEQVRMAVLPTRSETERFDIADKALADYQNLLTRWGKDPEAQADYQRARIDRLG
HHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALLVRHQTADLIKEYEAMEAEGYKMPDYARRWAASAYIDRRLPEKAAPILSSLYYSDGKT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
FRNSDDLLDADDLYYSLNESEQLDKAYQFAVNYSEQTPYQVGVYGLPGKEPNDDWIEGQT
CCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHCCHH
LLVQSLVALNDLPTAQKKLEDLSSTAPANQNLRIALASIYLARDLPRKAEQELKAVESLA
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHC
PRSLILERAQAETAMALQEWHQMELLTDDVISRSPEDIPSQELDRQRKVHNMYELRVSGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEECCC
RVISSNSPVSGNKDYGVETLLYSPPIAENWRVFGGGSYNNGQFEEGTGISRILRLGGEWT
EEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCC
SRDHWVEGEISNQNYGNGNGNKVGARLSTWYDLNDHWRVGGQVERLAKDTPLRALKNKVT
CCCCEEECEECCCCCCCCCCCEECCEEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHC
ANSASAYVFWKADDKRDAELSVTPSRFSDGNNRWEYEFNGRQRIWTGPYLTADFNLGLAA
CCCCCEEEEEECCCCCCCEEEECCHHCCCCCCEEEEEECCCEEEEECCEEEEECCCCEEE
SQNSKEDVIYYNPKRDFAYVPAVTLNHIMYRRYKTIWSQQVQLGVGGYWEKNYGNGLVTT
CCCCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCEEEEE
AGYGQRVQWNDVIDTGVAVVYDKRPYDGKREHDVTLSFDLNYRF
CCCCCCEEEHHHHHCCEEEEEECCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]