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The map label for this gene is mviN [H]

Identifier: 170024392

GI number: 170024392

Start: 2395386

End: 2397014

Strand: Reverse

Name: mviN [H]

Synonym: YPK_2158

Alternate gene names: 170024392

Gene position: 2397014-2395386 (Counterclockwise)

Preceding gene: 170024393

Following gene: 170024391

Centisome position: 51.12

GC content: 50.83

Gene sequence:

>1629_bases
TTGATAACGGCGAATCCCCATTGGGTAGAGCAACGCCTGCAGACCGTAGGCGTTGGTATTTACAGCACATTAGAAAACAG
ATCAAAAGAACCTATGAATCTATTGAAATCACTGGCCGCCGTCAGTTCCATGACGATGTTTTCCCGCGTGCTGGGCTTTG
CCCGCGATGCCATCGTGGCACGGGTATTTGGTGCAGGTATGGCGACGGACGCCTTTTTTGTGGCATTTAAATTGCCTAAC
TTGCTGCGGCGAATATTTGCTGAAGGCGCATTTTCCCAAGCTTTTGTGCCTATTCTGGCTGAATACAAAAGCCAGCAAGG
GGAAGAGGCGACGCGAACATTAGTGGCTTATGTCTCTGGCCTGTTAACCTTGATATTGGCGGTCGTCACCGTCGCGGGGA
TGCTGGCCGCGCCTTGGGTGATCTTCATTTCCGCCCCCGGCTTTACTGATACACCGGATAAATTTGCTCTGACCTCGGCG
CTGTTACGGGTGACTTTCCCGTATATTTTGCTGATCTCATTGGCCTCGCTAGTCGGAGCGATCCTTAATACCTGGAACCG
TTTTTCTATTCCGGCTTTTGCGCCAACCCTCCTCAATGTCAGCATGATAGGTTTTGCGCTGTTTGCTGCGCCTCATTTCA
ACCCGCCGGTGATGGCATTGGCTTGGGCTGTGGTGGTGGGGGGAGTGTTACAATTAGGCTATCAACTCCCGCACCTAAAA
AAAATCGGCATGTTGGTATTACCTCGGCTGTCGCTACGTGATACCGGTGTTTGGCGGGTGATGCGCCAGATGGGGCCAGC
GATCCTCGGGGTATCAGTCAGTCAGATTTCCCTGATTATCAATACGATTTTTGCATCATTTTTGGTATCTGGTTCGGTCT
CCTGGATGTACTACGCTGACCGTCTGATGGAGTTCCCCTCCGGGGTGTTAGGGGGCGCGTTAGGTACTATCCTGCTGCCA
TCACTGGCAAAGAGTTTTTCCAGTGCTAATCATGATGAATATTCCAGATTGATGGATTGGGGGCTGCGTCTTTGCTTCTT
ACTGGCCTTGCCAAGCGCGGTGGCATTAGGAATTTTAGCTAAACCGCTAATCGTCTCGTTATTCCAATACGGGAAATTTA
GCGCGTTTGACACCCTGATGACACAACGGGCGCTGGTGGCCTATTCGGTGGGCTTGATGGGGTTGATCGTGGTGAAGGTT
CTGGCTCCGGGGTTTTATTCTCGTCAGAATATTAAAACGCCGGTAAAAATCGCGATTATTACCTTGATACTCACGCAAGT
CATGAACTTGATCTTCATTGGGCCGTTTAAACACGCGGGCTTATCACTGTCTATCGGCCTGGGGGCATGTTTGAATGCCA
GTTTGCTCTATTGGCAGCTACGTAAACAGAAAATTTTCCAGCCACAGCCGGGGTGGGCCATATTCCTGACTAAATTGGTC
ATCGGTGTTATCGCGATGTCTGCGGTGCTGCTAGGGTTACTGTGGGTCATGCCTGATTGGGATGTTGGCGGGATGGCGTA
TCGGTTGCTACGGTTATCTGCGGTTGTTGTTGCCGGTGCTAGCGCCTACTTTGCCATGTTGGCATTATTAGGCTTTAAAG
TGCGTGATTTTGCCCGTAGAACGGGCTGA

Upstream 100 bases:

>100_bases
GAAAATCGATTGGCTTCAGTAATTGGTTACACCTTGCAGTGGCTATTCATGATTCGATACGTAGACTGTTGCCAGTTTTG
CTATCGTCTTTAGGGCCGTG

Downstream 100 bases:

>100_bases
CCTTACTAATCAACTAATCAATCAGTATTAGTAATCCAAATAAATAATGTATTATATAGCCCGATAATTTCGGGCTTTTT
TACATATTTACAATACATAT

Product: integral membrane protein MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MITANPHWVEQRLQTVGVGIYSTLENRSKEPMNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPN
LLRRIFAEGAFSQAFVPILAEYKSQQGEEATRTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSA
LLRVTFPYILLISLASLVGAILNTWNRFSIPAFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLK
KIGMLVLPRLSLRDTGVWRVMRQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLP
SLAKSFSSANHDEYSRLMDWGLRLCFLLALPSAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKV
LAPGFYSRQNIKTPVKIAIITLILTQVMNLIFIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLV
IGVIAMSAVLLGLLWVMPDWDVGGMAYRLLRLSAVVVAGASAYFAMLALLGFKVRDFARRTG

Sequences:

>Translated_542_residues
MITANPHWVEQRLQTVGVGIYSTLENRSKEPMNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPN
LLRRIFAEGAFSQAFVPILAEYKSQQGEEATRTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSA
LLRVTFPYILLISLASLVGAILNTWNRFSIPAFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLK
KIGMLVLPRLSLRDTGVWRVMRQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLP
SLAKSFSSANHDEYSRLMDWGLRLCFLLALPSAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKV
LAPGFYSRQNIKTPVKIAIITLILTQVMNLIFIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLV
IGVIAMSAVLLGLLWVMPDWDVGGMAYRLLRLSAVVVAGASAYFAMLALLGFKVRDFARRTG
>Mature_542_residues
MITANPHWVEQRLQTVGVGIYSTLENRSKEPMNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPN
LLRRIFAEGAFSQAFVPILAEYKSQQGEEATRTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSA
LLRVTFPYILLISLASLVGAILNTWNRFSIPAFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLK
KIGMLVLPRLSLRDTGVWRVMRQMGPAILGVSVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLP
SLAKSFSSANHDEYSRLMDWGLRLCFLLALPSAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKV
LAPGFYSRQNIKTPVKIAIITLILTQVMNLIFIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLV
IGVIAMSAVLLGLLWVMPDWDVGGMAYRLLRLSAVVVAGASAYFAMLALLGFKVRDFARRTG

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=510, Percent_Identity=85.2941176470588, Blast_Score=863, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 58855; Mature: 58855

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]