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The map label for this gene is mdtJ

Identifier: 170024365

GI number: 170024365

Start: 2362034

End: 2362477

Strand: Reverse

Name: mdtJ

Synonym: YPK_2131

Alternate gene names: 170024365

Gene position: 2362477-2362034 (Counterclockwise)

Preceding gene: 170024366

Following gene: 170024364

Centisome position: 50.38

GC content: 46.4

Gene sequence:

>444_bases
GTGATTTATTGGATATTTTTAGGTCTGGCAATTATTGCTGAAATTATTGGCACCCTATCAATGAAATATGCCAGTGTTAG
CGGCGAGATGACCGGGCATATCGTGATGTATTTTATGATAACGGGTTCCTATGTCATGCTCTCGTTAGCGGTTAAGAAAG
TAGCATTGGGTGTGGCTTATGCGCTGTGGGAGGGGATCGGCATCCTTATTATTACTATTTTCAGTGTGATGTGGTTTGGC
GAGACGTTATCGCCACTGAAAATAGCCGGTTTAGTGACACTGATTGGTGGGATCCTCTTGGTGAAATCGGGTACGCGGAA
ACCAAAACAACCGAACCGCCATCGCGGTAATCGACCCCCTTCGGTACAGGGATTAAAAACACAGACTACCGGCCATCATA
AGGGTGTTGCTGTTGAGTCAGGTGAGCATCATGCAGCAGCTTGA

Upstream 100 bases:

>100_bases
ACGGACTGCGCAGGTTTATTCCTTGTGAATAAGGCACTGAAGCAGGATAGCCGTAACAAATAGACCTTAGCGTGCGTTTA
TGCGTGTTAGGAGAAGAAAA

Downstream 100 bases:

>100_bases
GTTTTACCCTATAGCTTTCTTGATCTTGGCCGTTATGCTGGAAATCGTCGCTAATATCTTGCTGAAAATGTCAGATGGCT
TTCGCCGAAAATGGTTGGGG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITIFSVMWFG
ETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA

Sequences:

>Translated_147_residues
MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITIFSVMWFG
ETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA
>Mature_147_residues
MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITIFSVMWFG
ETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily

Homologues:

Organism=Escherichia coli, GI1787884, Length=111, Percent_Identity=67.5675675675676, Blast_Score=143, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTJ_YERP3 (A7FIB5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400993.1
- GeneID:   5387512
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2020
- NMPDR:   fig|349747.3.peg.518
- eggNOG:   COG2076
- HOGENOM:   HBG740972
- OMA:   AFWEGLG
- ProtClustDB:   CLSK889088
- BioCyc:   YPSE349747:YPSIP31758_2020-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01598
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 15833; Mature: 15833

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x183c6250)-; HASH(0x181b9eec)-; HASH(0x17f2ab9c)-; HASH(0x17dc9c90)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
SVQGLKTQTTGHHKGVAVESGEHHAAA
CCCCCCCCCCCCCCCEEEECCCCCCCH
>Mature Secondary Structure
MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
SVQGLKTQTTGHHKGVAVESGEHHAAA
CCCCCCCCCCCCCCCEEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA