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The map label for this gene is udg [H]

Identifier: 170024312

GI number: 170024312

Start: 2306589

End: 2307935

Strand: Reverse

Name: udg [H]

Synonym: YPK_2077

Alternate gene names: 170024312

Gene position: 2307935-2306589 (Counterclockwise)

Preceding gene: 170024313

Following gene: 170024311

Centisome position: 49.22

GC content: 42.76

Gene sequence:

>1347_bases
ATGAAGGTTACGGTTTTTGGTATTGGTTATGTGGGACTTGTTCAAGCTACAGTGCTTGCCGAGGTGGGGCATGATGTCCT
TTGTATCGATATTGATGCTAATAAAGTTGCCGATTTGAAAAAAGGCCGTATTGCTATTTTTGAGCCGGGCTTGGCTCCGT
TGGTCAAAGAAAACTATGAGGCAGGCAGATTACAGTTTTCAACAGATGCGCAAGCTGGTGTGGCACATGGCGTCATTCAA
TTTATTGCTGTGGGTACACCTCCTGATGAAGACGGTGCTGCCGATCTTAAATATGTCCTTGATGTGGCCAGTACCATTGG
CACGTATATGGACTCACCTAAGGTCATTATCGATAAATCTACAGTGCCCGTGGGGACAGCGGATAAAGTACATCAAGTTA
TACAAGCTATTTTGGAGCAGCGCGGTGAGAAGATAGATTTTAGTGTGGTATCAAATCCTGAGTTTTTAAAAGAGGGGGCC
GCAGTTGCTGATTGTAAACGGCCTGAACGTATTGTTATTGGTATTGATACGGATGACAGTGGTGCTCTAGAGTTAATCAG
TGAATTATACGAACCTTTTAATCGAAATCATGATCGTATGCTAGTAATGGATATCCGTAGTGCAGAACTGACAAAGTATG
CTGCAAACGGCATGCTGGCAACGAAAATAAGTTTCATGAATGAGATTGCTAATATTGCTGAGCGATTAGGGGCTGATATC
GAAAAAGTTCGACAGGGCATCGGTTCCGATTCACGTATTGGATACCATTTCATTTATTCTGGTTGTGGTTATGGGGGGTC
TTGTTTCCCAAAAGACATCCAAGCATTAATTCGTACTGCAGAAGATAAGGGTTATAAGCCCCAGCTATTGCAGGCTGTCG
AGCAAATCAATAATCAGCAGAAGTATAAGTTAACTGAATTCATTAAAAGTCATTTTAATTCGCAGTTAGCTGGAAAAACA
TTTGCTGTCTGGGGATTGGCCTTTAAGCCCAACACCGATGATATGCGTGAGGCACCGAGCCGTGTGGTAATGGAATCATT
GTGGGAAGCCGGGGCTACAATTCAAGCATACGATCCCGAAGCAATGGATGAGACGCAACGCATTTATGGTGCAAGAGATG
ATTTGAGATTAATGGGGACTAAAGAGTCTGCATTACAGGGAGCTGATGCCTTGATTATTTGTACTGAATGGCAAAGTTTT
CGTGCTCCAGATTTTGATATGATCAAGTCAAGGTTAAAGCACCCTGTTATTTTTGATGGGCGTAATTTGTACGATCCAGA
ACGCCTAAATAGTCGTGGGTTCACTTATTATGGAATTGGGCGTGGTGTTTCGATTAATCTATCATAG

Upstream 100 bases:

>100_bases
TTTTCGATAACAGTTTGTCACCTCAGGATAAATTAAGGTTAATTTCCGATAATCACTGGGAGTAAGTCTGGTATTGAATT
TCAACTCGGAGATCGAGCGA

Downstream 100 bases:

>100_bases
TAAGTGAGAATGCTGATTTTATGTGTTGATTACAAAACGTTAGTTAAATTTTCGCACTTGATTTTCATGTGTATGACCGA
AAATCAGTCGCTAACAGAAC

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYEAGRLQFSTDAQAGVAHGVIQ
FIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKSTVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGA
AVADCKRPERIVIGIDTDDSGALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADI
EKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAGKT
FAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPEAMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSF
RAPDFDMIKSRLKHPVIFDGRNLYDPERLNSRGFTYYGIGRGVSINLS

Sequences:

>Translated_448_residues
MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYEAGRLQFSTDAQAGVAHGVIQ
FIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKSTVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGA
AVADCKRPERIVIGIDTDDSGALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADI
EKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAGKT
FAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPEAMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSF
RAPDFDMIKSRLKHPVIFDGRNLYDPERLNSRGFTYYGIGRGVSINLS
>Mature_448_residues
MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYEAGRLQFSTDAQAGVAHGVIQ
FIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKSTVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGA
AVADCKRPERIVIGIDTDDSGALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADI
EKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAGKT
FAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPEAMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSF
RAPDFDMIKSRLKHPVIFDGRNLYDPERLNSRGFTYYGIGRGVSINLS

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=469, Percent_Identity=34.1151385927505, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI296040438, Length=371, Percent_Identity=35.8490566037736, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI296040443, Length=316, Percent_Identity=37.0253164556962, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=26.1792452830189, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=30.1939058171745, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=34.6320346320346, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136908, Length=466, Percent_Identity=35.6223175965665, Blast_Score=255, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49337; Mature: 49337

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYE
CEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCEEEECCCCCHHHHCCCC
AGRLQFSTDAQAGVAHGVIQFIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKS
CCCEEECCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGAAVADCKRPERIVIGIDTDDS
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCCHHCCCCCCEEEEEECCCCC
GALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADI
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQ
HHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCH
KYKLTEFIKSHFNSQLAGKTFAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPE
HHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCH
AMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSFRAPDFDMIKSRLKHPVIFDG
HHHHHHHHHCCCCCEEEECCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEECC
RNLYDPERLNSRGFTYYGIGRGVSINLS
CCCCCHHHHCCCCCEEEECCCCEEEECC
>Mature Secondary Structure
MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAIFEPGLAPLVKENYE
CEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCEEEECCCCCHHHHCCCC
AGRLQFSTDAQAGVAHGVIQFIAVGTPPDEDGAADLKYVLDVASTIGTYMDSPKVIIDKS
CCCEEECCCCHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECC
TVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGAAVADCKRPERIVIGIDTDDS
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHCCCCHHCCCCCCEEEEEECCCCC
GALELISELYEPFNRNHDRMLVMDIRSAELTKYAANGMLATKISFMNEIANIAERLGADI
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EKVRQGIGSDSRIGYHFIYSGCGYGGSCFPKDIQALIRTAEDKGYKPQLLQAVEQINNQQ
HHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCH
KYKLTEFIKSHFNSQLAGKTFAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQAYDPE
HHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCH
AMDETQRIYGARDDLRLMGTKESALQGADALIICTEWQSFRAPDFDMIKSRLKHPVIFDG
HHHHHHHHHCCCCCEEEECCCHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEECC
RNLYDPERLNSRGFTYYGIGRGVSINLS
CCCCCHHHHCCCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]