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The map label for this gene is aroH [H]

Identifier: 170024080

GI number: 170024080

Start: 2040805

End: 2041851

Strand: Reverse

Name: aroH [H]

Synonym: YPK_1841

Alternate gene names: 170024080

Gene position: 2041851-2040805 (Counterclockwise)

Preceding gene: 170024081

Following gene: 170024058

Centisome position: 43.54

GC content: 50.72

Gene sequence:

>1047_bases
ATGTACAAGACAGATGAACTGCGGACCGCTCGCATCGATAGCTTGATTACACCGCAGCAACTGGCTGAAAAGTTACCGAT
TTCTGAGGTTATTGCAGATAACGTGACAGCGTCACGTAAACGAATAGAGAAAATACTTATTGGTGAAGACCCACGTCTAC
TCGTGGTGATTGGCCCCTGCTCTATTCACGACCTTGATGCAGCCGTTGATTATGCCACCCGGCTCAAGGTGCTACGAGAA
CGCTATCAAGACCGGCTGGAAATCGTGATGCGCACCTATTTCGAGAAACCACGGACTGTAGTGGGTTGGAAGGGGCTGAT
TTCTGATCCGGCACTTGACGGCTCATGCCAGGTGAACTTGGGTATTGAACTGGCACGTAAGCTACTGTTAGCCGTGAATG
AACTCGGGCTGCCGACCGCTACCGAGTTCCTCGATATGGTAACAGGCCAATATATTGCCGACCTCATCAGTTGGGGGGCA
ATAGGCGCACGTACCACCGAAAGCCAGATCCACCGAGAGATGGCCTCGGCACTCTCCTGCCCCGTGGGTTTCAAAAATGG
TACAGATGGCAATGTGCGTATTGCTATTGATGCCATTCGCGCCGCACAAGCCAGCCATATGTTCCTTTCTCCGGATAAAA
CCGGCCAAATGACGATTTACCAAACCAGTGGTAACCCCTATGGGCATATTATTATGCGGGGTGGCAAGCAACCTAACTAT
GATGCCTCTGATATCGCAGCCGCCTGTGACAGCTTGCGGGAATTTGATTTGCCAGAACATCTGGTGGTGGATTTTAGCCA
CGGCAATTGCCAGAAGATGCATCGCCGCCAGTTGGATGTTGCCGAAAATATCGGGCTACAGATCCGTGCGGGTTCAACAG
CGATTGTCGGTGTTATGGCTGAGAGTTTCCTGATTGAGGGCACACAGAAGATTGTTGCCGGACAGCCCTTAACTTATGGG
CAATCCATCACTGACCCTTGCCTGAATTGGGATGATACTGAACAACTGTTAAGCCTATTGGCAGATGCAGTAAACAGCCG
GTTTTAA

Upstream 100 bases:

>100_bases
TACAGTGATGACGGTTGAATTCATGTGATTTTGGTTTATTGTGATCGCCATCACTTCCCGGTATTTCTGCCGCAGAGAAG
AACAGATTTAGAGAGTTTTC

Downstream 100 bases:

>100_bases
TTCATTCGCACGGGCTTTAATGAGTAAACCGTACATTAAATGAATACCTTCGGGATAGGGAAAAGTTAACGTTGTCGGGT
TAACTTTTTCTATCCCTATT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MYKTDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVNSRF

Sequences:

>Translated_348_residues
MYKTDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVNSRF
>Mature_348_residues
MYKTDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVNSRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=80.4597701149425, Blast_Score=589, Evalue=1e-170,
Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=58.6705202312139, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1788953, Length=337, Percent_Identity=51.3353115727003, Blast_Score=346, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=46.7048710601719, Blast_Score=306, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=44.4759206798867, Blast_Score=293, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38298; Mature: 38298

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKTDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPC
CCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDLDAAVDYATRLKVLRERYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEE
GIELARKLLLAVNELGLPTATEFLDMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
CCCCCCCCCCCEEEEEEEHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMA
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ESFLIEGTQKIVAGQPLTYGQSITDPCLNWDDTEQLLSLLADAVNSRF
HHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYKTDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPC
CCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDLDAAVDYATRLKVLRERYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEE
GIELARKLLLAVNELGLPTATEFLDMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
CCCCCCCCCCCEEEEEEEHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMA
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ESFLIEGTQKIVAGQPLTYGQSITDPCLNWDDTEQLLSLLADAVNSRF
HHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]