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The map label for this gene is ygcS [H]

Identifier: 170023893

GI number: 170023893

Start: 1834456

End: 1835814

Strand: Reverse

Name: ygcS [H]

Synonym: YPK_1652

Alternate gene names: 170023893

Gene position: 1835814-1834456 (Counterclockwise)

Preceding gene: 170023897

Following gene: 170023892

Centisome position: 39.15

GC content: 47.83

Gene sequence:

>1359_bases
ATGCAAACATTACCATCAGAAAAAATCAAGATGGACGATGTCCCCCTAAATCGCTTCCATATAAGAATTGCCGGGCTAAC
TTTTGGCGCACACTTTATCGATGGCTATATCTTAGGTCTGATTGGCTTTGCATTAATTCAACTCAAACCCATAATGGCAC
TTACACCATTATGGGAGGGATTACTCGGATCAGCCGCGCTGATCGGGCTATTTCTAGGCAGCCTAATATTAGGCTGGATC
TCAGATTACATTGGCCGCCAGAAAATTTTCAGTTTCAGTTTTGTCATCATTACCTTAGCCTCAGCACTGCAATTTTTTGC
CAGTACACCAGAACAGTTATTTATTTTGCGGGTCATCGTTGGTATTGGTATCGGTGGCGATTACTCGGTGGGACATACTT
TATTAGCTGAATTTTCACCACGAAAACATCGCGGGGTCTTATTGGGCGCATTCAGTGTCATTTGGACCTTTGGCTATGTT
AGTGCCAGTTTCGTTGGACATTATCTGAGTATGGTCAGCCCCGAGGCTTGGCGTTGGTTGTTATCTTCTGCCGCCCTGCC
CGCTTTACTTATTCTCCTGGTACGGATTGGTACGCCGGAGTCACCGCGCTGGCTAATGGGAAAAGGTCGTGAGGACGATG
CCATGGCCATTGTGCATAAGTACTTTGGCCCGAACGTAACGTTGATTGATGAGGAACCCGCGACTTCCACCCGCCGTTTT
CTGTCTTTATTTGGCCGTAAATACTGGCGACGTACCGCTTTTAATAGCTTATTTTTTGTTTGTCTGGTGATCCCCTACTT
CGCGATCTATACCTTTTTACCCTCGATTCTTAACGTGATGGCGTTGAGCCAGAATTTTGCTACCGACTTGTTATTGAACG
GCTTGCTCGTGGTGGGTGCTTTAGTCGGTATTGTCCTGACTGCATTCTGCTCGCGCCGTAGCTTCCTGATCTCTTCCTTT
ATTTTCCTGGCTACCTGCCTACTCTTGCTGAGCATACTGCCTTCCAATCAAACATTTTGGCTGATTGCACTCTTCGCGGC
TTTTACTCTTGTGATGTCTGCCGTCAGTAACCTAGTCGGTGTGTTCCCGGCCGAGAGTTTCCCGACCGAAGTACGCTCAA
TGGGGGTGGGATTTGCGACTTCCATGAGTCGCTTGGGATCAGCTATTGGTACCAGCCTGCTGCCATTAGCCATTGTCAAT
TATGGAATGCCCGTAACCACCACCCTCTTGGCATTCGTTTTAATTATTGGAGCCATCGTTTCTATCGCTTGGGCACCGGA
AACGAAAGGACTCACCCTCGTTGATGCCTCACAATCAGCAACCACACCACGCCCACCGTCCAGCATTATTCCAAACTGA

Upstream 100 bases:

>100_bases
TAGCTACTTCCATAATAGAAAAATAGTTAGCAAATAGCAGACAAGTGCTTGTTCCTATTGGTAACACAGTCAGTGGCGAA
TACAAAATGAGGGAATGTAA

Downstream 100 bases:

>100_bases
ATGTCCGTAGCGCTATGGTCGATACAAACGATACAGGAGGAACAGCATGCAAATGTATATTGGCGAAGGTTTTGCAGGTA
ACGGGGTGAATGCCGCCCAT

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MQTLPSEKIKMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWI
SDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYV
SASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRF
LSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSF
IFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVN
YGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN

Sequences:

>Translated_452_residues
MQTLPSEKIKMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWI
SDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYV
SASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRF
LSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSF
IFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVN
YGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN
>Mature_452_residues
MQTLPSEKIKMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWI
SDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYV
SASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRF
LSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSF
IFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVN
YGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507005, Length=386, Percent_Identity=25.3886010362694, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4506999, Length=451, Percent_Identity=24.1685144124169, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI302148518, Length=427, Percent_Identity=23.1850117096019, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI203098995, Length=232, Percent_Identity=29.7413793103448, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI24497490, Length=380, Percent_Identity=27.1052631578947, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI213021148, Length=466, Percent_Identity=23.8197424892704, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI7662270, Length=230, Percent_Identity=30, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI24308167, Length=458, Percent_Identity=26.2008733624454, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI23510410, Length=372, Percent_Identity=23.9247311827957, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI8923870, Length=398, Percent_Identity=25.1256281407035, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI296080719, Length=374, Percent_Identity=23.2620320855615, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24497499, Length=374, Percent_Identity=23.2620320855615, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI296080721, Length=374, Percent_Identity=23.2620320855615, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI296080734, Length=340, Percent_Identity=24.7058823529412, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI11415038, Length=402, Percent_Identity=24.3781094527363, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI166197673, Length=357, Percent_Identity=24.3697478991597, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI24497497, Length=400, Percent_Identity=25.5, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI90669191, Length=400, Percent_Identity=25.5, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI262399383, Length=170, Percent_Identity=30.5882352941176, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI20070188, Length=401, Percent_Identity=20.6982543640898, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24497476, Length=392, Percent_Identity=20.9183673469388, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI216548223, Length=189, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI21553331, Length=316, Percent_Identity=23.1012658227848, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082159, Length=438, Percent_Identity=61.8721461187215, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1786229, Length=432, Percent_Identity=36.3425925925926, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1788068, Length=464, Percent_Identity=25, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788074, Length=461, Percent_Identity=24.295010845987, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790463, Length=190, Percent_Identity=31.0526315789474, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082404, Length=394, Percent_Identity=24.3654822335025, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1789207, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082231, Length=419, Percent_Identity=24.582338902148, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789312, Length=458, Percent_Identity=24.4541484716157, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17565976, Length=208, Percent_Identity=28.8461538461538, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17565978, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980584, Length=374, Percent_Identity=25.9358288770053, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71980582, Length=374, Percent_Identity=25.9358288770053, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988651, Length=206, Percent_Identity=30.0970873786408, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560496, Length=397, Percent_Identity=24.9370277078086, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=449, Percent_Identity=24.7216035634744, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193207197, Length=399, Percent_Identity=24.812030075188, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193209824, Length=358, Percent_Identity=25.4189944134078, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71989531, Length=390, Percent_Identity=24.1025641025641, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989525, Length=390, Percent_Identity=24.1025641025641, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212645980, Length=354, Percent_Identity=25.1412429378531, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554160, Length=408, Percent_Identity=24.5098039215686, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=464, Percent_Identity=21.9827586206897, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320595, Length=191, Percent_Identity=32.4607329842932, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320745, Length=207, Percent_Identity=28.0193236714976, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321100, Length=416, Percent_Identity=21.1538461538462, Blast_Score=63, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24649618, Length=341, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640198, Length=459, Percent_Identity=24.6187363834423, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640196, Length=459, Percent_Identity=24.6187363834423, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640200, Length=459, Percent_Identity=24.6187363834423, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649622, Length=411, Percent_Identity=24.5742092457421, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668456, Length=390, Percent_Identity=25.8974358974359, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922616, Length=403, Percent_Identity=25.5583126550869, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649616, Length=396, Percent_Identity=25.5050505050505, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI161077756, Length=456, Percent_Identity=21.9298245614035, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922874, Length=392, Percent_Identity=23.469387755102, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647365, Length=324, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078338, Length=324, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658792, Length=396, Percent_Identity=23.7373737373737, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 49207; Mature: 49207

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLPSEKIKMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEG
CCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWL
HHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRF
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHH
LSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIV
HCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIAWAPETKGLTLVDASQSATTPRPPSSIIPN
HHHCCCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTLPSEKIKMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEG
CCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWL
HHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRF
HHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHH
LSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIV
HCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIAWAPETKGLTLVDASQSATTPRPPSSIIPN
HHHCCCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]