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The map label for this gene is yajO [H]

Identifier: 170023891

GI number: 170023891

Start: 1832876

End: 1833895

Strand: Reverse

Name: yajO [H]

Synonym: YPK_1650

Alternate gene names: 170023891

Gene position: 1833895-1832876 (Counterclockwise)

Preceding gene: 170023892

Following gene: 170023884

Centisome position: 39.11

GC content: 47.16

Gene sequence:

>1020_bases
ATGGATTACATTAAGTTGGGTCATTGCGGTCTGCAAGTTTCACGGCTTTGCCTTGGCACCATGAATATGGGCAGCAAACA
GTGGAAACCCTGGGTTTTTGATAAAGCAGAAAGCACGCCACTGATCAAACACGCTCTAGATTGTGGGATAAATTTTATCG
ATTTGGCTGACTTCTATTCCGCTGGAGTAGGTGAAGAAGTGGTTGGGCGCATCGTGAAAAATTTGATGTCGCGTGATGAG
TTGGTGCTAACGACTAAAGTAGGTTACCCAATAGGTCATGGCCCGAATAATCAGGGACATTCCCGTAAGCATATAATGGC
CAGTATTGATGCCAGCCTGAAACGGTTGGGTACCGATTATATCGATATCTATATGCTGCACTACTTCGATATCAATACTC
CAGTTGAAGAAACCTGGTCGGCAATGAACGACATTATTCATTCCGGTAAAGCCCGTTATACCGGCGTTTCCACCATGTTT
ACCTGGCAACTGAGTAAAATTTTATGGTGCTGCGAACGTAATGGTTTTGCCAAACCGATCAATATGCAATTACAGCTTAA
CTGCGCCTACCGAGAAGAAGAGCGGGAGATGATCCCACAATGTCGCGATCAAGGCTTGGGGATTTCCGCATTTAGCCCAC
TGGCGCGCGGCTTACTCAGTTGCGATTTCAGTTCAGTACGCAATAAGACAGATTTTTTCACTCAGGAGATGTATGCCGAT
GTCACCTCACTGAATATTGCGCAATCTGTCGAACGGGTTGCAAAAAATCGTGGCATTACTCCCGCTCAGGTTGCTCAAGC
CTGGGTGCTTAATCACCCAGGAACCGACTGCATGTTAGTGGGGGCCGATACTATCGAACAGATCAACAGTGCTGTTACCG
CTCTGAGAATTTCACTCAACGCCGAAGAAAATTTTGAATTGGAGCGTAACTACACCCCGTGCGATGTTATTAATGATTAC
ACCGCAGGCCAGCGGATCGCGCGGGAAGCTCGCCCGCCAAGCGGTATTTTTGCCCCATAA

Upstream 100 bases:

>100_bases
CATGCAGCCATGGCAAAAACACCAAAACGTGATCAACTAACACATGCATTGACGCAACTGAGCAACCCCTTCTTTACCCC
CAAAGCCTGAGGATTAACTG

Downstream 100 bases:

>100_bases
AATAGCTGATATACGTGATTCTTTAACTATTGGCCAGTGCAACATAAAATCAATACGTTAACACTGGCCAAAAAGAATCA
AAACCAAGGGATCGTGGCAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDE
LVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMF
TWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYAD
VTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEENFELERNYTPCDVINDY
TAGQRIAREARPPSGIFAP

Sequences:

>Translated_339_residues
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDE
LVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMF
TWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYAD
VTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEENFELERNYTPCDVINDY
TAGQRIAREARPPSGIFAP
>Mature_339_residues
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDE
LVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMF
TWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYAD
VTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEENFELERNYTPCDVINDY
TAGQRIAREARPPSGIFAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=317, Percent_Identity=30.9148264984227, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=30.7936507936508, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436964, Length=309, Percent_Identity=29.126213592233, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI27436962, Length=309, Percent_Identity=29.126213592233, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=28.8025889967638, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=28.7096774193548, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI223718702, Length=209, Percent_Identity=30.622009569378, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41152114, Length=208, Percent_Identity=32.2115384615385, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41327764, Length=302, Percent_Identity=25.8278145695364, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI223718708, Length=170, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=41.1764705882353, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1789375, Length=311, Percent_Identity=33.1189710610932, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788070, Length=319, Percent_Identity=30.0940438871473, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=26.0233918128655, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788081, Length=270, Percent_Identity=30, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994888, Length=327, Percent_Identity=25.3822629969419, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=23.1023102310231, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=239, Percent_Identity=25.9414225941423, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=33.2344213649852, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=25.077399380805, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=25.2525252525253, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=323, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321052, Length=152, Percent_Identity=28.2894736842105, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640980, Length=339, Percent_Identity=27.7286135693215, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45549126, Length=339, Percent_Identity=27.4336283185841, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=27.741935483871, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24657054, Length=245, Percent_Identity=27.7551020408163, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24663317, Length=348, Percent_Identity=26.4367816091954, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646159, Length=230, Percent_Identity=29.1304347826087, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644950, Length=268, Percent_Identity=23.8805970149254, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129731, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37945; Mature: 37945

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYS
CCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHHHHHH
AGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
IDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPI
HEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
NMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYAD
EEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
VTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHEEEEEC
AEENFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
CCCCCEECCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYS
CCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHHHHHH
AGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
IDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPI
HEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
NMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYAD
EEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
VTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHEEEEEC
AEENFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
CCCCCEECCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]