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The map label for this gene is yfbQ [H]

Identifier: 170023799

GI number: 170023799

Start: 1720966

End: 1722180

Strand: Reverse

Name: yfbQ [H]

Synonym: YPK_1558

Alternate gene names: 170023799

Gene position: 1722180-1720966 (Counterclockwise)

Preceding gene: 170023815

Following gene: 170023798

Centisome position: 36.72

GC content: 49.22

Gene sequence:

>1215_bases
ATGTCCCCCATTGAGAAATCCAGCAAACTGGACAACGTCTGTTATGACATTCGTGGACCGGTGCTAAAAGAAGCTAAGCG
TCTTGAAGAGGAAGGTAACAAGGTTCTGAAACTGAACATCGGCAACCCTGCCCCGTTTGGTTTCGATGCACCCGACGAGA
TTCTGGTGGATGTAATCCGTAATTTACCGACCGCACAAGGCTATTGCGACTCCAAAGGCTTGTTTTCGGCACGTAAAGCC
ATTATGCAACACTATCAAGCCCGCGATATCCGTGATCTGACGGTCGAGGATATCTACATTGGAAACGGTGTTTCCGAGTT
GATCGTTCAATCTATGCAAGCATTACTGAATTTGGGTGATGAAATGCTGGTGCCCGCACCGGATTACCCGCTGTGGACAG
CAGCTGTGTCGCTCTCAAGTGGTAAAGCGGTTCATTATATGTGTGATGAAGAATCAGGCTGGTTCCCTGATTTGGATGAT
ATTCGCAGCAAAATCACTCCGCGTACCCGTGGGATTGTGATTATCAACCCGAATAACCCAACCGGTGCGGTATACAGCAA
AGAGCTGCTGTTAGAAATTGTTGAAATCGCTCGCCAGAATGACCTGATTATTTTCGCTGATGAGATCTACGATAAGATTT
TGTATGACGATGCTCAGCACCATTCGATCGCCGCATTAGCCCCTGATTTGCTGACCGTTACGTTCAATGGGCTGTCTAAA
ACTTACCGTGTTGCGGGTTTCCGCCAGGGTTGGATGGTGTTGAACGGGCCGAAAAAGCACGCTAAAGGGTATATTGAAGG
CTTGGAAATGCTGGCATCGATGCGTTTGTGCGCCAACGTGCCAATGCAGCATGCGATTCAAACCGCCTTGGGCGGCTATC
AGAGCATTAGTGAGTTTATCCAACCTGGTGGCCGTTTGTACGAGCAGCGTGATCGGGCCTGGGAGCTTATCAACCAAATC
CCCGGTGTTTCCTGTGTGAAACCTCAGGGCGCGTTGTATATGTTCCCACGCATTGATCAGAAACGTTTTAACCTGAAAGA
CGATCAGAAATTGGTATTGGATCTGTTGTTGCAAGAGAAAGTGCTATTGGTGCAAGGTAGCGCCTTTAACTGGCCGTACC
CGGACCATGTGCGGATCGTCACGTTGCCACGGGTGGATGAGCTAGAGATGGCGGTGAGAAAGCTGGGGCGGTTCTTAGAG
ACGTATCATCAGTAA

Upstream 100 bases:

>100_bases
ATGTATAGAACTTCAAAAATCAGTGGCGTCGGAGTACATTGAGCACCTTGCAGTGTTCCACGCTGAGGACACGCTTTTAC
CAGCAAAAGGCTCATTTTTT

Downstream 100 bases:

>100_bases
TTGTATGATTGGGGGATGAGGGCTGTTGATGAATCACTAAATCATCATCAACTGGAGCCTGATCCCCCGAACAAGTCAAT
TAATGTCAACCGAAACCCAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSPIEKSSKLDNVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTAQGYCDSKGLFSARKA
IMQHYQARDIRDLTVEDIYIGNGVSELIVQSMQALLNLGDEMLVPAPDYPLWTAAVSLSSGKAVHYMCDEESGWFPDLDD
IRSKITPRTRGIVIINPNNPTGAVYSKELLLEIVEIARQNDLIIFADEIYDKILYDDAQHHSIAALAPDLLTVTFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFIQPGGRLYEQRDRAWELINQI
PGVSCVKPQGALYMFPRIDQKRFNLKDDQKLVLDLLLQEKVLLVQGSAFNWPYPDHVRIVTLPRVDELEMAVRKLGRFLE
TYHQ

Sequences:

>Translated_404_residues
MSPIEKSSKLDNVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTAQGYCDSKGLFSARKA
IMQHYQARDIRDLTVEDIYIGNGVSELIVQSMQALLNLGDEMLVPAPDYPLWTAAVSLSSGKAVHYMCDEESGWFPDLDD
IRSKITPRTRGIVIINPNNPTGAVYSKELLLEIVEIARQNDLIIFADEIYDKILYDDAQHHSIAALAPDLLTVTFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFIQPGGRLYEQRDRAWELINQI
PGVSCVKPQGALYMFPRIDQKRFNLKDDQKLVLDLLLQEKVLLVQGSAFNWPYPDHVRIVTLPRVDELEMAVRKLGRFLE
TYHQ
>Mature_403_residues
SPIEKSSKLDNVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTAQGYCDSKGLFSARKAI
MQHYQARDIRDLTVEDIYIGNGVSELIVQSMQALLNLGDEMLVPAPDYPLWTAAVSLSSGKAVHYMCDEESGWFPDLDDI
RSKITPRTRGIVIINPNNPTGAVYSKELLLEIVEIARQNDLIIFADEIYDKILYDDAQHHSIAALAPDLLTVTFNGLSKT
YRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFIQPGGRLYEQRDRAWELINQIP
GVSCVKPQGALYMFPRIDQKRFNLKDDQKLVLDLLLQEKVLLVQGSAFNWPYPDHVRIVTLPRVDELEMAVRKLGRFLET
YHQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=27.7777777777778, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI19263340, Length=470, Percent_Identity=25.9574468085106, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI215599424, Length=376, Percent_Identity=27.3936170212766, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4885351, Length=436, Percent_Identity=24.5412844036697, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI95147551, Length=268, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881279, Length=268, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=299, Percent_Identity=24.7491638795987, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI56713254, Length=299, Percent_Identity=24.7491638795987, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI169881281, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=89.8514851485149, Blast_Score=768, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=26.5789473684211, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786816, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=28.1842818428184, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=464, Percent_Identity=25.4310344827586, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=184, Percent_Identity=30.9782608695652, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=184, Percent_Identity=30.9782608695652, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=25.5972696245734, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=242, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=361, Percent_Identity=29.3628808864266, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=357, Percent_Identity=28.8515406162465, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=357, Percent_Identity=22.6890756302521, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=26.5789473684211, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24641770, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24641760, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24641768, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24641766, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24641764, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI45551451, Length=483, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=24.1486068111455, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=24.1486068111455, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=24.1486068111455, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=24.1486068111455, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45529; Mature: 45398

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIEKSSKLDNVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLFSARKAIMQHYQARDIRDLTVEDIYIGNGVSELIVQSMQALLNLGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYMCDEESGWFPDLDDIRSKITPRTRGIVIINPNNP
CEEECCCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKELLLEIVEIARQNDLIIFADEIYDKILYDDAQHHSIAALAPDLLTVTFNGLSK
CCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCHH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
QPGGRLYEQRDRAWELINQIPGVSCVKPQGALYMFPRIDQKRFNLKDDQKLVLDLLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHHCC
VLLVQGSAFNWPYPDHVRIVTLPRVDELEMAVRKLGRFLETYHQ
EEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIEKSSKLDNVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYCDSKGLFSARKAIMQHYQARDIRDLTVEDIYIGNGVSELIVQSMQALLNLGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVSLSSGKAVHYMCDEESGWFPDLDDIRSKITPRTRGIVIINPNNP
CEEECCCCCCHHHHEEECCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKELLLEIVEIARQNDLIIFADEIYDKILYDDAQHHSIAALAPDLLTVTFNGLSK
CCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCHH
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
QPGGRLYEQRDRAWELINQIPGVSCVKPQGALYMFPRIDQKRFNLKDDQKLVLDLLLQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHHCC
VLLVQGSAFNWPYPDHVRIVTLPRVDELEMAVRKLGRFLETYHQ
EEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]