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The map label for this gene is yfdZ [H]

Identifier: 170023687

GI number: 170023687

Start: 1598003

End: 1599238

Strand: Direct

Name: yfdZ [H]

Synonym: YPK_1446

Alternate gene names: 170023687

Gene position: 1598003-1599238 (Clockwise)

Preceding gene: 170023685

Following gene: 170023688

Centisome position: 34.08

GC content: 50.97

Gene sequence:

>1236_bases
ATGGCTGAATTACCTGCTAAACGTCGTTTTACCCGTATTGATCGTCTCCCCCCGTATGTTTTTAATATTACTTCTGAGCT
AAAGATGGCTGCCCGGCGTCGGGGCGAAGATATTATTGACTTCAGTATGGGCAATCCTGACGGCCCGACACCGCCGCATA
TCGTTGAGAAAATGTGCAGTGTCGCGCAACGTGAAGATACTCACGGTTATTCAACTTCGCGGGGAATACCGCGCCTGCGT
AGAGCGATTTCCCGTTGGTATGCCGATCGCTATCAGGTGGATATCGATCCCGAAAATGAAGCTATCGTCACTATCGGCTC
TAAAGAAGGGCTGGCTCACCTGATGCTGGCAACGCTGGATCACGGGGATACGGTACTGGTGCCAAACCCCAGCTACCCGA
TTCACATTTATGGTGCCGTGATCGCCGGTGCGCAAGTGCGTTCAGTGCCGTTGACCGAAGGCATTGATTTTTTTGGCGAG
CTGGAACGCGCTATCCGTGAAACCATTCCTAAACCCAAAATGATGATCCTCGGTTTTCCATCCAACCCAACAGCGCAATG
TGTTGAGTTGGATTTTTTTGAGCGAGTCGTCGCGCTGGCGAAGCAATACGATGTGCTGGTGGTGCATGATCTGGCTTATG
CAGACATCGTTTATGATGGCTGGAAAGCGCCGTCAATTATGCAGGTGCCGGGCGCGAAGGATATTGCGGTAGAATTCTTC
ACGCTATCCAAAAGTTACAATATGGCTGGTTGGCGGATTGGTTTTATGGTCGGCAATCCTGAATTGGTCAGTGCCCTGGC
CCGAATTAAGAGTTATCACGATTACGGCACGTTCACGCCATTACAGGTAGCCGCGATTGCAGCATTGGAAGGCGATCAGC
AATGTGTCCGTGATATTGCTGAGCAATACCGCCAGCGACGTAATGCCTTAGTGCGTGGGCTACATGAGGCCGGCTGGATG
GTTGATAATCCCAAAGCCTCAATGTATGTCTGGGCAAAAATCCCAGAGCCTTATGCACATTTAGGTTCGCTGGAGTTCGC
TAAACGCTTGCTGGCAGAGGCGAAGGTGTGTGTCTCGCCGGGGATTGGCTTTGGTGACTACGGTGACACGCATGTGCGTT
TTGCCTTAATTGAAAATCAGGACCGTATTCGTCAGGCGGTACGTGGGATTAAGAGCATGTTTCGTGCTGATGGTTTACTG
AAACCGGGCAAATCTTCCCCCAATGAAATGGCCTAA

Upstream 100 bases:

>100_bases
ACTCGACACTTATTCAGCGCTAGGATATGTTCATAAACAGACCATCTGATGGTCAGCGTCGCTCGGACGGTCCGGGCGCT
AACGTATCCTCGAGGAATTT

Downstream 100 bases:

>100_bases
TCAAACAAAGTCGATTAGCCAGTAACTTACATTTTGGTAAGGCGCTTAGGTGTTTTGCCAAAATGCAGCTCTATCACCAA
AATGCAGCTCTATCACCAAA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAELPAKRRFTRIDRLPPYVFNITSELKMAARRRGEDIIDFSMGNPDGPTPPHIVEKMCSVAQREDTHGYSTSRGIPRLR
RAISRWYADRYQVDIDPENEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLTEGIDFFGE
LERAIRETIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNALVRGLHEAGWM
VDNPKASMYVWAKIPEPYAHLGSLEFAKRLLAEAKVCVSPGIGFGDYGDTHVRFALIENQDRIRQAVRGIKSMFRADGLL
KPGKSSPNEMA

Sequences:

>Translated_411_residues
MAELPAKRRFTRIDRLPPYVFNITSELKMAARRRGEDIIDFSMGNPDGPTPPHIVEKMCSVAQREDTHGYSTSRGIPRLR
RAISRWYADRYQVDIDPENEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLTEGIDFFGE
LERAIRETIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNALVRGLHEAGWM
VDNPKASMYVWAKIPEPYAHLGSLEFAKRLLAEAKVCVSPGIGFGDYGDTHVRFALIENQDRIRQAVRGIKSMFRADGLL
KPGKSSPNEMA
>Mature_410_residues
AELPAKRRFTRIDRLPPYVFNITSELKMAARRRGEDIIDFSMGNPDGPTPPHIVEKMCSVAQREDTHGYSTSRGIPRLRR
AISRWYADRYQVDIDPENEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLTEGIDFFGEL
ERAIRETIPKPKMMILGFPSNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFT
LSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYRQRRNALVRGLHEAGWMV
DNPKASMYVWAKIPEPYAHLGSLEFAKRLLAEAKVCVSPGIGFGDYGDTHVRFALIENQDRIRQAVRGIKSMFRADGLLK
PGKSSPNEMA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=418, Percent_Identity=24.1626794258373, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI56713256, Length=418, Percent_Identity=24.1626794258373, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI95147551, Length=354, Percent_Identity=24.0112994350282, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169881279, Length=354, Percent_Identity=24.0112994350282, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169881281, Length=173, Percent_Identity=23.6994219653179, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788722, Length=411, Percent_Identity=88.0778588807786, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=337, Percent_Identity=26.1127596439169, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788627, Length=379, Percent_Identity=26.3852242744063, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=398, Percent_Identity=25.3768844221106, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788332, Length=228, Percent_Identity=28.5087719298246, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=23.6180904522613, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=370, Percent_Identity=24.5945945945946, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=370, Percent_Identity=24.5945945945946, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=23.6702127659574, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=24.5714285714286, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=20.5128205128205, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573069, Length=382, Percent_Identity=24.869109947644, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646114, Length=382, Percent_Identity=24.869109947644, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573067, Length=382, Percent_Identity=24.869109947644, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573065, Length=382, Percent_Identity=24.869109947644, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641770, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=401, Percent_Identity=24.4389027431421, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551451, Length=401, Percent_Identity=24.4389027431421, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45896; Mature: 45765

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELPAKRRFTRIDRLPPYVFNITSELKMAARRRGEDIIDFSMGNPDGPTPPHIVEKMCS
CCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSRGIPRLRRAISRWYADRYQVDIDPENEAIVTIGSKEGLAHLMLATLD
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLTEGIDFFGELERAIRETIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYRQRRNALVRGLHEAGWMVDNPKASMYVWAKIPEPYAHLGSLEFAKRLLAEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCC
GIGFGDYGDTHVRFALIENQDRIRQAVRGIKSMFRADGLLKPGKSSPNEMA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AELPAKRRFTRIDRLPPYVFNITSELKMAARRRGEDIIDFSMGNPDGPTPPHIVEKMCS
CCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
VAQREDTHGYSTSRGIPRLRRAISRWYADRYQVDIDPENEAIVTIGSKEGLAHLMLATLD
HHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLTEGIDFFGELERAIRETIPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SNPTAQCVELDFFERVVALAKQYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFF
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYRQRRNALVRGLHEAGWMVDNPKASMYVWAKIPEPYAHLGSLEFAKRLLAEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCC
GIGFGDYGDTHVRFALIENQDRIRQAVRGIKSMFRADGLLKPGKSSPNEMA
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]