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The map label for this gene is ompR [H]

Identifier: 170023666

GI number: 170023666

Start: 1573443

End: 1574126

Strand: Direct

Name: ompR [H]

Synonym: YPK_1424

Alternate gene names: 170023666

Gene position: 1573443-1574126 (Clockwise)

Preceding gene: 170023663

Following gene: 170023667

Centisome position: 33.55

GC content: 47.51

Gene sequence:

>684_bases
ATGAAAATTTTGTTAGTCGATGATGATCTTGAACTGGGCACGATGTTGAAGGAATATTTGGGCGGAGAGGGGTTTACTGC
CAAACATGTATTGACCGGCAAAGCGGGCATTGATGGAGCCTTGTCCGGCGATTACACCGCGCTTATCCTCGACATTATGT
TGCCTGATATGAGTGGTATTGATGTATTACGGCAAGTGCGTAAAAAAAGCCGTTTGCCGATCATTATGTTAACGGCTAAA
GGCGACAATATTGATCGGGTGATCGGTCTTGAAATGGGCGCGGATGACTACATGCCTAAACCGTGCTATCCACGTGAATT
GGTGGCTCGATTACGCGCTGTTTTACGCCGTTTTGAAGAGCAGCCAACTTTGTCCTCCATTGATAGCGGTATTATCACGC
AAGGCGGATTGACACTTAACCCCTCTACCCGCAGTAGCGAATGGCAGGGTAAACCGTTTGATCTGACCGCATCGGAATTC
AATCTATTAGAGCTGCTGCTACGTTCACCTGAACGCGTGGTGACTAAAGACGAACTATCTGATAAAGGGTTAGGGCGGCC
TCGCGAAGCCTATGACCGTAGTGTCGATGTGCATATCAGTAATATTCGCCAGAAACTCGCCGCCCTACCGGGTAATCATT
TAAATATTGAAACGGTACGTAGCATTGGCTATCGCATCCGATAA

Upstream 100 bases:

>100_bases
GGTTAAGTGAGATTCAAGATTATGTAAGGATTGAGTAAAACTGGCTGCATGGTATTGGAATAGGCACGAAAATAGCTGGA
ATCAGGTAGGGGAGTTAAAA

Downstream 100 bases:

>100_bases
CCGTCACTGCGGAGTGAGATAACCTATGCGCGGAAGATTATTCTGGAAAATCCTGTTGGGTTTTTGGCTGACGTTTATTT
TGATGACTCAGATGTTGTGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPTLSSIDSGIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR

Sequences:

>Translated_227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPTLSSIDSGIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
>Mature_227_residues
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGIDVLRQVRKKSRLPIIMLTAK
GDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEEQPTLSSIDSGIITQGGLTLNPSTRSSEWQGKPFDLTASEF
NLLELLLRSPERVVTKDELSDKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=41.1504424778761, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=42.6666666666667, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=36.1607142857143, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.0530973451327, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.7777777777778, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.0869565217391, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=35.5555555555556, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787229, Length=213, Percent_Identity=35.2112676056338, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.4821428571429, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=29.7777777777778, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.5309734513274, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=31.6666666666667, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25232; Mature: 25232

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGI
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCH
DVLRQVRKKSRLPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
QPTLSSIDSGIITQGGLTLNPSTRSSEWQGKPFDLTASEFNLLELLLRSPERVVTKDELS
CCCHHHHCCCCEECCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
DKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
CCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MKILLVDDDLELGTMLKEYLGGEGFTAKHVLTGKAGIDGALSGDYTALILDIMLPDMSGI
CEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCH
DVLRQVRKKSRLPIIMLTAKGDNIDRVIGLEMGADDYMPKPCYPRELVARLRAVLRRFEE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
QPTLSSIDSGIITQGGLTLNPSTRSSEWQGKPFDLTASEFNLLELLLRSPERVVTKDELS
CCCHHHHCCCCEECCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCC
DKGLGRPREAYDRSVDVHISNIRQKLAALPGNHLNIETVRSIGYRIR
CCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]