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The map label for this gene is yhjB [H]

Identifier: 170023662

GI number: 170023662

Start: 1566589

End: 1568049

Strand: Direct

Name: yhjB [H]

Synonym: YPK_1420

Alternate gene names: 170023662

Gene position: 1566589-1568049 (Clockwise)

Preceding gene: 170023661

Following gene: 170023663

Centisome position: 33.41

GC content: 39.29

Gene sequence:

>1461_bases
ATGAATGCGCCATTAATTATAATATGTACATTCTTCCTGTTTAGTATTTATCTTGCCATTCGCTCTAAAAAAGGCAAGAA
GATGGACCATGAAGGGTGGACCACCGGTGGCCGTAGCTACGGCGCTTTATTAGTATTTCTACTGAGTGCTGGGGAGATAT
ACACAACATTTACATTCTTGGGGGGCAGTGGCTGGGCTTATGGAAAAGGCCCAGCCATATTATATACGCTCACCGTTAAT
GCCTTTATGGGGATATCACTTTATTGGCTTCATCCTATTATTTGGAAGTATGCTAAAGATAATAATGTTAGGTCTATTTC
AGACTTCTTCGCACTGAAATATAAAAGTTCATCATTAGGTATACTGATTAGCATATTCTCTATCGCTGCAATGGTTCCGC
TTTTCATTTTACAATTAAAAGGACTTGGGATCATTGTCTCACAAGCATCTTATGGCTCTATATCGTCCAATATGGCAATA
TGGATTGGCGTGATTTCAGTCTCTGTTTTTGTGATGATTTCTGGAATTCATGGTTCTGCCTGGACATCTGTATTAAAAGA
TTTCATGATATTGTTTGTGGTTGTCTTTATCGGTATTTATATTCCAATTCACTACTACGGTAGTATTGGCAACATGTTTC
AATCTATTGAAACAGTTAATCCTGGGTATCTTGTCTTCCCGAAAGAAGGACTCAACATACCTTGGTATATCTCTACCGTA
TTCTTATCCGTAGCCGCTTATTTCTGTTGGCCACACTATATGACGGCTGTATTTACAGCCAAAAATGAAACCTCATTAAA
GCGTAATAGCATACTGATTCCGGCTTACAGTCTGGTCATGCTGTTTGCCTTTTTTGTCGGTTTTGCGGCAATCTTAAATG
TCCCTGACTTAACCGGGCCAGATGTTGACCTGGCTTTATTTGAAATATCAAAATCAACCTTCTCAAGTTATATTGTTGGG
TTTATTGGTGCGGCAGGTATGCTGACAGCACTGGTACCGGGTTCTATGTTATTACTGGCGACGGCAAATATGCTGGCCGG
TGTCGTCCAAAAGATTTTCCGCCTGGATGTGGAGAAAAATAAATCGGGAAATCTTTCTCGCTATATGGTGCCTGTTGTTG
CCTTGGTCTCTTTGTATTTTATCTTTAATGGCAATGATACGCTGGTCGCTATAATGCTACTTGGTGTCAATATAATTGCT
CAGTTCTTCCCAGCGCTTATATTCAGTTTTTGCAAAAAGAATCCAATCACGACTGCGGGCGCTTTTTCGGGGATTATGGT
CGGTGTCATTATTTTGGCGGTCACCTATGTCTATCATATTTCAATAGAAGATATTTTCCCGTTCATTACTAATGGCTTTG
AGTATATGAATATTGGGGTTGTCGCCTTTGCTATGAACTTTATCGTTACTTTCTTCATCTCATATTTAACAAGAAGCTAT
TATAAAGAAGTCACTGTTTAA

Upstream 100 bases:

>100_bases
TGCCATTCCTTATGTTCTGGATCGTGATTTGGTTGATTCTGACCGCATTGATTATGGCCATAATCTCGAAATTGGATTCA
AATATAAGTAAGGAGGAAGT

Downstream 100 bases:

>100_bases
TAACCAATAGGCCATTTTCAAACTGGAAGTGGCCGTCCTAATCTGAGTGATAAAGAGTTATGGGAAAAACAATTGTTATC
GTCGGTGGTGTTGCCGGTGG

Product: Na+/solute symporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNAPLIIICTFFLFSIYLAIRSKKGKKMDHEGWTTGGRSYGALLVFLLSAGEIYTTFTFLGGSGWAYGKGPAILYTLTVN
AFMGISLYWLHPIIWKYAKDNNVRSISDFFALKYKSSSLGILISIFSIAAMVPLFILQLKGLGIIVSQASYGSISSNMAI
WIGVISVSVFVMISGIHGSAWTSVLKDFMILFVVVFIGIYIPIHYYGSIGNMFQSIETVNPGYLVFPKEGLNIPWYISTV
FLSVAAYFCWPHYMTAVFTAKNETSLKRNSILIPAYSLVMLFAFFVGFAAILNVPDLTGPDVDLALFEISKSTFSSYIVG
FIGAAGMLTALVPGSMLLLATANMLAGVVQKIFRLDVEKNKSGNLSRYMVPVVALVSLYFIFNGNDTLVAIMLLGVNIIA
QFFPALIFSFCKKNPITTAGAFSGIMVGVIILAVTYVYHISIEDIFPFITNGFEYMNIGVVAFAMNFIVTFFISYLTRSY
YKEVTV

Sequences:

>Translated_486_residues
MNAPLIIICTFFLFSIYLAIRSKKGKKMDHEGWTTGGRSYGALLVFLLSAGEIYTTFTFLGGSGWAYGKGPAILYTLTVN
AFMGISLYWLHPIIWKYAKDNNVRSISDFFALKYKSSSLGILISIFSIAAMVPLFILQLKGLGIIVSQASYGSISSNMAI
WIGVISVSVFVMISGIHGSAWTSVLKDFMILFVVVFIGIYIPIHYYGSIGNMFQSIETVNPGYLVFPKEGLNIPWYISTV
FLSVAAYFCWPHYMTAVFTAKNETSLKRNSILIPAYSLVMLFAFFVGFAAILNVPDLTGPDVDLALFEISKSTFSSYIVG
FIGAAGMLTALVPGSMLLLATANMLAGVVQKIFRLDVEKNKSGNLSRYMVPVVALVSLYFIFNGNDTLVAIMLLGVNIIA
QFFPALIFSFCKKNPITTAGAFSGIMVGVIILAVTYVYHISIEDIFPFITNGFEYMNIGVVAFAMNFIVTFFISYLTRSY
YKEVTV
>Mature_486_residues
MNAPLIIICTFFLFSIYLAIRSKKGKKMDHEGWTTGGRSYGALLVFLLSAGEIYTTFTFLGGSGWAYGKGPAILYTLTVN
AFMGISLYWLHPIIWKYAKDNNVRSISDFFALKYKSSSLGILISIFSIAAMVPLFILQLKGLGIIVSQASYGSISSNMAI
WIGVISVSVFVMISGIHGSAWTSVLKDFMILFVVVFIGIYIPIHYYGSIGNMFQSIETVNPGYLVFPKEGLNIPWYISTV
FLSVAAYFCWPHYMTAVFTAKNETSLKRNSILIPAYSLVMLFAFFVGFAAILNVPDLTGPDVDLALFEISKSTFSSYIVG
FIGAAGMLTALVPGSMLLLATANMLAGVVQKIFRLDVEKNKSGNLSRYMVPVVALVSLYFIFNGNDTLVAIMLLGVNIIA
QFFPALIFSFCKKNPITTAGAFSGIMVGVIILAVTYVYHISIEDIFPFITNGFEYMNIGVVAFAMNFIVTFFISYLTRSY
YKEVTV

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53572; Mature: 53572

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLIIICTFFLFSIYLAIRSKKGKKMDHEGWTTGGRSYGALLVFLLSAGEIYTTFTFL
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEE
GGSGWAYGKGPAILYTLTVNAFMGISLYWLHPIIWKYAKDNNVRSISDFFALKYKSSSLG
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCCCH
ILISIFSIAAMVPLFILQLKGLGIIVSQASYGSISSNMAIWIGVISVSVFVMISGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
WTSVLKDFMILFVVVFIGIYIPIHYYGSIGNMFQSIETVNPGYLVFPKEGLNIPWYISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
FLSVAAYFCWPHYMTAVFTAKNETSLKRNSILIPAYSLVMLFAFFVGFAAILNVPDLTGP
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVDLALFEISKSTFSSYIVGFIGAAGMLTALVPGSMLLLATANMLAGVVQKIFRLDVEKN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KSGNLSRYMVPVVALVSLYFIFNGNDTLVAIMLLGVNIIAQFFPALIFSFCKKNPITTAG
CCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AFSGIMVGVIILAVTYVYHISIEDIFPFITNGFEYMNIGVVAFAMNFIVTFFISYLTRSY
HHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKEVTV
HHHCCC
>Mature Secondary Structure
MNAPLIIICTFFLFSIYLAIRSKKGKKMDHEGWTTGGRSYGALLVFLLSAGEIYTTFTFL
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEE
GGSGWAYGKGPAILYTLTVNAFMGISLYWLHPIIWKYAKDNNVRSISDFFALKYKSSSLG
CCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCCCH
ILISIFSIAAMVPLFILQLKGLGIIVSQASYGSISSNMAIWIGVISVSVFVMISGIHGSA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
WTSVLKDFMILFVVVFIGIYIPIHYYGSIGNMFQSIETVNPGYLVFPKEGLNIPWYISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
FLSVAAYFCWPHYMTAVFTAKNETSLKRNSILIPAYSLVMLFAFFVGFAAILNVPDLTGP
HHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVDLALFEISKSTFSSYIVGFIGAAGMLTALVPGSMLLLATANMLAGVVQKIFRLDVEKN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KSGNLSRYMVPVVALVSLYFIFNGNDTLVAIMLLGVNIIAQFFPALIFSFCKKNPITTAG
CCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AFSGIMVGVIILAVTYVYHISIEDIFPFITNGFEYMNIGVVAFAMNFIVTFFISYLTRSY
HHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKEVTV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]