Click here to switch to the map view.

The map label for this gene is rpiR [C]

Identifier: 170023648

GI number: 170023648

Start: 1549134

End: 1550012

Strand: Direct

Name: rpiR [C]

Synonym: YPK_1406

Alternate gene names: 170023648

Gene position: 1549134-1550012 (Clockwise)

Preceding gene: 170023647

Following gene: 170023649

Centisome position: 33.03

GC content: 48.69

Gene sequence:

>879_bases
GTGAAAACTGGTGCTCCCCGCTTTAAGCCAGGTAAAATTCTTGATGCCTTGGGTGCGATGCAAAATAGCCTGACTCGTTC
TGCTCAGCGTATTGCTGCGTATATTTTGGCGCAACCGGCTCAGGTTACCCAATTATCTATTGCTGATCTCTCGGCACTCA
CACAGGCCGGTGAAGCGACCATTATTCGTTTCTGTCGGACACTGGGTTATAAAGGGTTTCAGGATTTCAAAATGGACCTG
GCCATTGAAGTGGCCACCCGCCATAACAGTGAAAACAGCCTGTTAGATGCCGATGTCCAAGAGGGTGACGATACGCTGGC
GATCGGCAGCAAATTACAATCCGCTATCAATAATGTTTTATCTGAAACACTTAATTTGCTTTCTATTGAGAGTGTTGAAC
AGGTGGTCAAATTGCTGCGTCCTGCGGATCGCATCTGTATTTTTGGTGTTGGCTCCTCGGGGATCACTGCGGAAGATGCC
AAAGGCAAACTAATGCGCATCGGCCTGCGGGTTGATGCTGCGACAAATAATCACTTCATGTATATGCAAGCCTCTCTTAT
GAACCCTGGTGATGTTGCCATTGGTATCAGTCATTCGGGGACCTCGGCTGAAACTGTGCAGGCCCTCAAATTGGCAAAAG
AGGCTGGGGCGACGACAGTGGCGTTGACGCATAATATGGGGTCACGGATCACTGAATTAGCCGATTATGTCCTGATCAAT
GGTAACCGGCAGGGGCAATTGCAGGGGGACTCCATCGGTACAAAAATCGCACAATTGTTTGTGTTGGATCTGATTTACGC
CTTATTGGTCAAAGCTGATCCGGCGCAGGCGGAGAGTATTAAACGCAAAACAACCCAAGCGGTTAGCCAAAATGGATGA

Upstream 100 bases:

>100_bases
ACACCTCCACCATTGATCTTCACGAAACAGGTCAACTATGTAATGATGCGCCTCAAATATATCATCCTGTCTGTCATTTT
ATTTCCCTTGAGGTGTCCGC

Downstream 100 bases:

>100_bases
CCGGTAATCTACCCGCCATACGTCAAGCTGCATGTGCGTAGGCGGCCTTGGTGACTCGGCCCGTCCATGGGCCTCGCCTC
TCCGCTGCAAGCCGCGTTCA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKTGAPRFKPGKILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEATIIRFCRTLGYKGFQDFKMDL
AIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVLSETLNLLSIESVEQVVKLLRPADRICIFGVGSSGITAEDA
KGKLMRIGLRVDAATNNHFMYMQASLMNPGDVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLIN
GNRQGQLQGDSIGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAVSQNG

Sequences:

>Translated_292_residues
MKTGAPRFKPGKILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEATIIRFCRTLGYKGFQDFKMDL
AIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVLSETLNLLSIESVEQVVKLLRPADRICIFGVGSSGITAEDA
KGKLMRIGLRVDAATNNHFMYMQASLMNPGDVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLIN
GNRQGQLQGDSIGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAVSQNG
>Mature_292_residues
MKTGAPRFKPGKILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEATIIRFCRTLGYKGFQDFKMDL
AIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVLSETLNLLSIESVEQVVKLLRPADRICIFGVGSSGITAEDA
KGKLMRIGLRVDAATNNHFMYMQASLMNPGDVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLIN
GNRQGQLQGDSIGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAVSQNG

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=271, Percent_Identity=26.9372693726937, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788767, Length=263, Percent_Identity=27.3764258555133, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082130, Length=251, Percent_Identity=28.2868525896414, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788159, Length=213, Percent_Identity=30.5164319248826, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31116; Mature: 31116

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGAPRFKPGKILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEAT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
IIRFCRTLGYKGFQDFKMDLAIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVL
HHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEECHHHCCCCHHHHHHHHHHHHHHHH
SETLNLLSIESVEQVVKLLRPADRICIFGVGSSGITAEDAKGKLMRIGLRVDAATNNHFM
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCEEE
YMQASLMNPGDVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLIN
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEC
GNRQGQLQGDSIGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAVSQNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTGAPRFKPGKILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEAT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHH
IIRFCRTLGYKGFQDFKMDLAIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVL
HHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEECHHHCCCCHHHHHHHHHHHHHHHH
SETLNLLSIESVEQVVKLLRPADRICIFGVGSSGITAEDAKGKLMRIGLRVDAATNNHFM
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCEEE
YMQASLMNPGDVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLIN
EEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEC
GNRQGQLQGDSIGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAVSQNG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]