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The map label for this gene is ipaH3 [H]

Identifier: 170023645

GI number: 170023645

Start: 1546281

End: 1547252

Strand: Reverse

Name: ipaH3 [H]

Synonym: YPK_1403

Alternate gene names: 170023645

Gene position: 1547252-1546281 (Counterclockwise)

Preceding gene: 170023656

Following gene: 170023643

Centisome position: 32.99

GC content: 37.14

Gene sequence:

>972_bases
ATGGGTTTAAATTGTTTTGGTATCAGTTTTTCATCACCGAATATTACTTTAGATAGTGACCCTACTCACCAGAAATTGTC
AAAATCTGGCTATCACGCTATATGGAAAGAGTGGAAAGAAAATGCAGTTCCCGGAGAAGGGGAACAGCGTGGTATTGCCG
TAGAAAGAATGAAATATTGCCTGAAAAAAAACTTAACCGAGCTCAACCTCAACAATCTTGGTTTACGTTCATTGCCCGAT
ATTTTACCCCCTTGTACAAAACTGGATATTTCAGATAACCAACTGTCGCAATTTCCAACGTTATCAACGGATCTGGTTAC
CCTTAATTTAGCCAATAATCAATGGGCAGAACTCCCAAATAAATTACCACCGTACTTGAAGTCTCTTAATGTTCAAAACG
GCCAACTCTTTGAACTCCCAGAACTACCAAATATGTTGGAGTTTCTACATGCAGATAATAATCAGCTACACTGCTTGCCA
GAAAAACTGCCAACATCTCTGCGTTTAATCACAGCAAGTAACAACCAAATCACCCAGTTACCTGAAGCTATCTTTGGTTT
ATTTAGTGACAGTAAAATCGTACTGAAGAATAATCCACTAACTAAAAAGACGTATTATTTCGCATATGGTTCCATTGTAC
CAAATATATCATTATCGCCCTCATGCCTAACAAAAATTGAATATTTACCTCCTAAACCACTTAGCGAGATAGTGAAAGTC
TGGCTAACACCAGAGCAACAAAAATCCTTAGAAAGTAAATGGCTGGAAATAGAGCAGGAACCCGGTGCAAAAGAATTTTC
AAAGTTTCTTAACCAACTAGCTAACATAAAAAAATCATCCATTAGGCCAAAACCTAATCTATTTTTACGAGAGCTTAGTC
CTAAAATAGGTGGAATGGATTCATGGTTATACGATTTAGTGAATTCATATCCTCTGCGTCAGAAAGCATTTTTAGACTAT
GGACATTTTTAG

Upstream 100 bases:

>100_bases
AGAAAAACTTAAAAAATAATTTAATATCAGTTTTTTCCCTTATACAGGAAGCCGTATTTATCAAGCAGTATGCCCCTGTT
AAAATAAGGAGCTTACTGTT

Downstream 100 bases:

>100_bases
ACTATGGACACTGAGTATCCTGTAACTCATTCCTTTTTCTGAATAGACCTCGGTAAGTTAACACCCTGTCCCCCATCAGC
GATAACTCAGTGGTGGGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MGLNCFGISFSSPNITLDSDPTHQKLSKSGYHAIWKEWKENAVPGEGEQRGIAVERMKYCLKKNLTELNLNNLGLRSLPD
ILPPCTKLDISDNQLSQFPTLSTDLVTLNLANNQWAELPNKLPPYLKSLNVQNGQLFELPELPNMLEFLHADNNQLHCLP
EKLPTSLRLITASNNQITQLPEAIFGLFSDSKIVLKNNPLTKKTYYFAYGSIVPNISLSPSCLTKIEYLPPKPLSEIVKV
WLTPEQQKSLESKWLEIEQEPGAKEFSKFLNQLANIKKSSIRPKPNLFLRELSPKIGGMDSWLYDLVNSYPLRQKAFLDY
GHF

Sequences:

>Translated_323_residues
MGLNCFGISFSSPNITLDSDPTHQKLSKSGYHAIWKEWKENAVPGEGEQRGIAVERMKYCLKKNLTELNLNNLGLRSLPD
ILPPCTKLDISDNQLSQFPTLSTDLVTLNLANNQWAELPNKLPPYLKSLNVQNGQLFELPELPNMLEFLHADNNQLHCLP
EKLPTSLRLITASNNQITQLPEAIFGLFSDSKIVLKNNPLTKKTYYFAYGSIVPNISLSPSCLTKIEYLPPKPLSEIVKV
WLTPEQQKSLESKWLEIEQEPGAKEFSKFLNQLANIKKSSIRPKPNLFLRELSPKIGGMDSWLYDLVNSYPLRQKAFLDY
GHF
>Mature_322_residues
GLNCFGISFSSPNITLDSDPTHQKLSKSGYHAIWKEWKENAVPGEGEQRGIAVERMKYCLKKNLTELNLNNLGLRSLPDI
LPPCTKLDISDNQLSQFPTLSTDLVTLNLANNQWAELPNKLPPYLKSLNVQNGQLFELPELPNMLEFLHADNNQLHCLPE
KLPTSLRLITASNNQITQLPEAIFGLFSDSKIVLKNNPLTKKTYYFAYGSIVPNISLSPSCLTKIEYLPPKPLSEIVKVW
LTPEQQKSLESKWLEIEQEPGAKEFSKFLNQLANIKKSSIRPKPNLFLRELSPKIGGMDSWLYDLVNSYPLRQKAFLDYG
HF

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway. Synthesizes a 'Lys-48'-linked ubiquitin chain, which requir

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted. Host cytoplasm (By similarity). Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 LRR (leucine-rich) repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001611 [H]

Pfam domain/function: PF00560 LRR_1 [H]

EC number: NA

Molecular weight: Translated: 36655; Mature: 36523

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNCFGISFSSPNITLDSDPTHQKLSKSGYHAIWKEWKENAVPGEGEQRGIAVERMKYC
CCCEEEEEEECCCCEEECCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LKKNLTELNLNNLGLRSLPDILPPCTKLDISDNQLSQFPTLSTDLVTLNLANNQWAELPN
HHCCCCEECCCCCCCHHHHHHCCCCCEECCCCCHHHHCCCCCCCEEEEEECCCHHHHCCC
KLPPYLKSLNVQNGQLFELPELPNMLEFLHADNNQLHCLPEKLPTSLRLITASNNQITQL
CCCHHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCEEECHHHCCCEEEEEEECCCCHHHH
PEAIFGLFSDSKIVLKNNPLTKKTYYFAYGSIVPNISLSPSCLTKIEYLPPKPLSEIVKV
HHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHHHH
WLTPEQQKSLESKWLEIEQEPGAKEFSKFLNQLANIKKSSIRPKPNLFLRELSPKIGGMD
HCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
SWLYDLVNSYPLRQKAFLDYGHF
HHHHHHHHCCCCHHHHHHCCCCC
>Mature Secondary Structure 
GLNCFGISFSSPNITLDSDPTHQKLSKSGYHAIWKEWKENAVPGEGEQRGIAVERMKYC
CCEEEEEEECCCCEEECCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LKKNLTELNLNNLGLRSLPDILPPCTKLDISDNQLSQFPTLSTDLVTLNLANNQWAELPN
HHCCCCEECCCCCCCHHHHHHCCCCCEECCCCCHHHHCCCCCCCEEEEEECCCHHHHCCC
KLPPYLKSLNVQNGQLFELPELPNMLEFLHADNNQLHCLPEKLPTSLRLITASNNQITQL
CCCHHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCEEECHHHCCCEEEEEEECCCCHHHH
PEAIFGLFSDSKIVLKNNPLTKKTYYFAYGSIVPNISLSPSCLTKIEYLPPKPLSEIVKV
HHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHHHH
WLTPEQQKSLESKWLEIEQEPGAKEFSKFLNQLANIKKSSIRPKPNLFLRELSPKIGGMD
HCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
SWLYDLVNSYPLRQKAFLDYGHF
HHHHHHHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12384590 [H]