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The map label for this gene is proX [H]

Identifier: 170023359

GI number: 170023359

Start: 1252000

End: 1253004

Strand: Reverse

Name: proX [H]

Synonym: YPK_1113

Alternate gene names: 170023359

Gene position: 1253004-1252000 (Counterclockwise)

Preceding gene: 170023360

Following gene: 170023356

Centisome position: 26.72

GC content: 48.66

Gene sequence:

>1005_bases
ATGCGCACGACAGGAATCTGGGCCTTGGCCCTCACCACACTGATCAGCTCTCAGTTATCCGCAGCAGAATTGTCGGGCAA
AGGTATCACCGTCCAGCCTCTGCAAAGCACCATTTCGGAAGAAACCTTCCAGACCTCGCTGGTCAATAAAGCGTTGGAAA
AACTCGGTTACGACGTCCAACCCACGAAAGAAGTCGATTACAATGTCGCCTACTCCTCCATTGCTGCAGGTGATGCAACC
TATCTGGCGGTAAATTGGGTGCCACTGCATAACGATCAATATAATGCAGCCGGTGGTGATGCTAAATTTTACCGGCAGGG
TAACTATATTGAAGGCTTGGCACAGGGTTATCTGATCGATAAAAAAACAGCCTACCAATACAACATCACCAATATTGCAC
AGTTAAAAGACCCGAAAATAGCCAAATTGTTTGATGCCAATAATGATGGCAAAGCCGATCTGACCGGCTGTAACCCCGGC
TGGGGTTGTGAGGCCCCAATTAACCATCAGATCAAAGCTTACGGCCTGAGCGATACGGTGACCCATAATCAGGGTAACTA
TGCCGCCATGATTGCCGATACCATTACCCGTTACAAAGAAGGCAAGCCCATTCTGTATTACACTTGGACGCCTTATTGGG
TCAGTGACGTATTGGTGCCGGGCCGTGATGTCGTGTGGCTACAAGTTCCCTTCTCTTCCTTGCCAGACAAAACTATCGAT
ACCCAGCTTTCTAATGGCGCGAACTATGGTTTCCCACCTAGCGTCATGCATATTGTGGCGAACAAAAAATGGGCTGAAGC
CAATCCGGCAGCCGCCAAGCTTTTCTCCATCATGAAATTATCTATTAATGATGTGAATGCTCAAAACATGCGGATGCACA
GTGGTGAATCCTCAGATGCCGATATTGAACGCCATGTAAATGGCTGGATCAACGCTCATCAGGCGACCTTCGATGGTTGG
GTAAAAACCGCGGCTGAAGCGGCTAATTCCCAAACGGCGCAGTAA

Upstream 100 bases:

>100_bases
ATACCACAGGGCCTGTTGGGTTGCTCACCAAACCCTTCTGTAACAGCAAATAATTTCAATTAATTACGCTCAAATAAAAT
AGCTTAAAAAAGGAAAAACT

Downstream 100 bases:

>100_bases
GTTAAGAGAAAACAGATACTTTCGGGTATCTGTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAACAGGCAGATCGTA
AAGACGCCGTAAATACATCC

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRTTGIWALALTTLISSQLSAAELSGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTAYQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ

Sequences:

>Translated_334_residues
MRTTGIWALALTTLISSQLSAAELSGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTAYQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ
>Mature_334_residues
MRTTGIWALALTTLISSQLSAAELSGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQPTKEVDYNVAYSSIAAGDAT
YLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLIDKKTAYQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPG
WGCEAPINHQIKAYGLSDTVTHNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDADIERHVNGWINAHQATFDGW
VKTAAEAANSQTAQ

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=328, Percent_Identity=71.3414634146341, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36594; Mature: 36594

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTGIWALALTTLISSQLSAAELSGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTKEVDYNVAYSSIAAGDATYLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLID
CCCCCCCEEEEHHCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCEEEE
KKTAYQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPGWGCEAPINHQIKAYGLSDTV
CCCEEEECCCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCE
THNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
ECCCCCEEEHHHHHHHHHHCCCCEEEEECCCHHHHHEECCCCCEEEEEECCCCCCCCHHH
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDA
HHHCCCCCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
DIERHVNGWINAHQATFDGWVKTAAEAANSQTAQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTTGIWALALTTLISSQLSAAELSGKGITVQPLQSTISEETFQTSLVNKALEKLGYDVQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTKEVDYNVAYSSIAAGDATYLAVNWVPLHNDQYNAAGGDAKFYRQGNYIEGLAQGYLID
CCCCCCCEEEEHHCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCEEEE
KKTAYQYNITNIAQLKDPKIAKLFDANNDGKADLTGCNPGWGCEAPINHQIKAYGLSDTV
CCCEEEECCCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCE
THNQGNYAAMIADTITRYKEGKPILYYTWTPYWVSDVLVPGRDVVWLQVPFSSLPDKTID
ECCCCCEEEHHHHHHHHHHCCCCEEEEECCCHHHHHEECCCCCEEEEEECCCCCCCCHHH
TQLSNGANYGFPPSVMHIVANKKWAEANPAAAKLFSIMKLSINDVNAQNMRMHSGESSDA
HHHCCCCCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
DIERHVNGWINAHQATFDGWVKTAAEAANSQTAQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]