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The map label for this gene is rlmG [H]

Identifier: 170022813

GI number: 170022813

Start: 617771

End: 618958

Strand: Direct

Name: rlmG [H]

Synonym: YPK_0562

Alternate gene names: 170022813

Gene position: 617771-618958 (Clockwise)

Preceding gene: 170022808

Following gene: 170022822

Centisome position: 13.17

GC content: 49.41

Gene sequence:

>1188_bases
ATGAGCCAACTCGATCTGGGAACGCAAAGCCTTGAGCTTGAGCGTTTTCCTCCACAAGAAAATTCCAATACCCTTCAGGC
GTGGGAAGCGGCAGATGAATATCTGCTACAAAACATTGATTTAAGCCAAATTGATGGCCGCCCGGTGCTGGTGTTTAACG
ATCAGTTTGGTACGCTGGCCTGCGCTTTACACGCTTATCGCCCGTTCAGTTCCAGTGACTCTTATATGAGTCAGTTGGCG
ACGGCGCATAATTTGCGTCTAAACCATTTAGATGAATCTGCGGTGACATTACTGAGCAGCGTCGATGACTTACCCGAGGC
ACCTAAGCTGGTGGTCATTAAGATCCCGAAAGCCTTAGCGCTACTCGAACATCAATTACGTGCTTTGCGTCGCGTTGTGG
CACCAGATACGGTGATCATTGCCGGTGCAAAATCCCGCGATGTGCATAACTCCACGCTGCAACTGTTTGAAAAGATCCTG
GGGCCAACCAAAACGACGCTGGCTTGGAAAAAAGCGCGGCTGATTCACTGCGAGGTTGCTGATATTCCATTGGCTGACGC
GCCGGAAACCATCGATTGGCCGCTGCCTAACACGGACTACATTATCCATAATCACGCGAACGTTTTCTCTCGCAATAATC
TGGATATTGGAGCGCGTTTCTTTATGGAAATCTTGCCTTATGATGTCACCGGTAAAATTGCGGATTTAGGTTGTGGGAAT
GGTGTCGTCGGGTTAATCGCACTGGAGCAAAACCCGCTAGCTGAAATGCTGTTTGTTGATGAATCCTATATGGCAGTGGC
ATCCAGTGAATTGAACATCACGGTTAACCGCCCGCAAGACTTGTCGCGCTGTGAATTTATGGTGAGCCATGGTTTGGCGG
GTGTGGAGCGTGAAAGCCTGCAATTGGTGTTATGTAATCCACCGTTCCACCAACAACATGCGGTCAGTGACCATGTCGCC
TGGCAGATGTTCTGTGATGCCAAGCGTTGTCTGAAAGCGGGTGGCGAGTTGATGATCGTGGGTAACCGCCATCTGGATTA
CTTCCATAAGCTCAAGCGTTTGTTTGGCAACTGCGAAACACTGGATTCAAACCAGAAATTTATGGTGCTGAAATCGGTTA
AGCAGGCCTCCTCTCGCTCAGAAGGCGGCGGTTCCGGTAGTCTCGATATGTCATATAGCGATTTCTAA

Upstream 100 bases:

>100_bases
TTGGCACAAGCGCGTTTAAAACGCATTAAAGCAAAAAAACATTTTACTGATCGCCCGTTTTAGGGGATAAACAGCCCAAA
TTTATTATTCAGGAGCGGTG

Downstream 100 bases:

>100_bases
TCGGTATTTCACAGGGTGGGGTTTTCGCCACACCCTGTGATTATTCTCAGTTCTATTGCTATTCTCGGCCCTGTTACGGC
CCTTTACCTTGCTGGTCGCG

Product: rRNA (guanine-N(2)-)-methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmG [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLACALHAYRPFSSSDSYMSQLA
TAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKIL
GPTKTTLAWKKARLIHCEVADIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGN
GVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVA
WQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF

Sequences:

>Translated_395_residues
MSQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLACALHAYRPFSSSDSYMSQLA
TAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKIL
GPTKTTLAWKKARLIHCEVADIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGN
GVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVA
WQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF
>Mature_394_residues
SQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLACALHAYRPFSSSDSYMSQLAT
AHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILG
PTKTTLAWKKARLIHCEVADIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGNG
VVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVAW
QMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF

Specific function: Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmG family [H]

Homologues:

Organism=Escherichia coli, GI87082206, Length=379, Percent_Identity=63.0606860158311, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1790830, Length=284, Percent_Identity=25.7042253521127, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR017237
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.174 [H]

Molecular weight: Translated: 43842; Mature: 43710

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLA
CCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCHHH
CALHAYRPFSSSDSYMSQLATAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALA
HHHHHCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHH
LLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILGPTKTTLAWKKARLIHCEVA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCEEEEEEEEC
DIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGN
CCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCCEEECCCCC
GVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESL
CEEEEEEECCCCCCCEEEECCCHHEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCE
QLVLCNPPFHQQHAVSDHVAWQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCET
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCC
LDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF
CCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLA
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCHHH
CALHAYRPFSSSDSYMSQLATAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALA
HHHHHCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCCCCCEEEEECCHHHH
LLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILGPTKTTLAWKKARLIHCEVA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHCEEEEEEEEC
DIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGN
CCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCCEEECCCCC
GVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESL
CEEEEEEECCCCCCCEEEECCCHHEEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCE
QLVLCNPPFHQQHAVSDHVAWQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCET
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCC
LDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF
CCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA