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The map label for this gene is uxaC [H]

Identifier: 170022805

GI number: 170022805

Start: 605239

End: 606648

Strand: Direct

Name: uxaC [H]

Synonym: YPK_0554

Alternate gene names: 170022805

Gene position: 605239-606648 (Clockwise)

Preceding gene: 170022793

Following gene: 170022806

Centisome position: 12.91

GC content: 50.85

Gene sequence:

>1410_bases
ATGTCGCAGTTTTTGACCGAAGACTTTTTGCTGGACACCGAGTTCGCCCGTCGTCTCTACCATGACTATGCAAAAGATCA
GCCGATCTTTGATTATCACTGCCATTTGCCGCCAGAACAGATCGCCGAAAACTACCGTTTTAAGAACATGTATGACATCT
GGTTGAAAGGTGACCACTATAAATGGCGAGCCATGCGGACCAACGGTGTTGCTGAGCGTCTGTGCACCGGCGATGCCAGT
GATCGTGAGAAGTTCGATGCTTGGGCTGCGACGGTTCCTCACACTATCGGTAACCCGTTGTACCATTGGACGCATCTTGA
ATTGCGCCGTCCGTTTGGTATTACCGGTAAGTTATTGTCCCCGGCGACATCTGAAGAGATCTGGCAACGCGGCAACGAAT
TATTAGCGCAAGACCCCTTCTCTGCGCGCGGCATTATGCAGCAGATGAATGTCAAAATGGTTGGGACCACTGACGACCCA
ATTGATGATCTGCGCCACCACAAAGCGATTGCCGCTGATGGCAGCTTCAACATCAAAGTGTTACCAAGCTGGCGTCCCGA
CAAAGCGTTTAATATTGAAGCAGCGGGTTTTAACGATTATATGCAGCGGCTTGAAGCGGCTGCGGATACCTCAATCAGCC
GTTTTGCCGATCTGTGCGTGGCATTGAATAAGCGTATGGACCACTTTGCCGCCCACGGTTGTAAAGTCTCTGACCATGCG
TTGGATGTGGTGGTATACGGCGAGGCGGATGAAACCACACTGGATGCTATTTTGGCACGCCGTCTGGCTGGCAATCAGCC
AAGTACAGAAGAAATTGCGCAGTTTAAAACCGCAGTATTACTGTTCTTGTCTGGTGAATATCATCGTCGTGAATGGGTAC
AGCAGTATCACATTGGTGCGCTACGTAATAATAACAGCCGCATGTTTAACCTGGTGGGGCCGGATATCGGCTTTGACTCC
ATCAATGACCAACCGCTGGCGCAGCCGCTGTCTCGGCTGTTAGATGCACAGGGTCTGCGCAATGCCCTGCCAAAAACAAT
CCTTTACTGCCTGAATCCGCGTGATAACGAAGTGATCGGTACCATGGTCGGCAACTTCCAGGGCGAAGGTGAAGCAGGAA
AAATGCAGTTTGGTTCCGGCTGGTGGTTTAACGACCAAAAAGACGGTATGCAGCGCCAGATGACCCAACTTGCTCAGCTT
GGTCTATTGAGCCGCTTTGTTGGAATGCTCACTGATAGCCGTAGTTTCTTGTCTTATACCCGCCATGAGTATTTCCGTCG
CATTCTTTGCCAGATGATTGGCCGCTGGGTCGCGGACGGTGAAGCACCGGCCGATATTGCGTTACTGGGGGCGATGGTGA
AAAACATTTGCTTCGATAATGCGCAGCAATATTTCGCCATCGAACTGTAA

Upstream 100 bases:

>100_bases
CAATATCTATAAAAATGCTGGACGATAGATTTAATTGGTGTGATAACTTTGCGATAACAGAAAGCCGTACTCTGAGATGT
ACTCATCTGAGGAATCCATA

Downstream 100 bases:

>100_bases
TCACTCAAGCAGATTTAATCACTCAATCAATTTTAATAACGGGGCCAATAGTTGGCTCCATATAACTCTAACGTATTGTT
TATTTAACGCTTGGCTGCAC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHYKWRAMRTNGVAERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDP
IDDLRHHKAIAADGSFNIKVLPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHA
LDVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGALRNNNSRMFNLVGPDIGFDS
INDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIGTMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL

Sequences:

>Translated_469_residues
MSQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHYKWRAMRTNGVAERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDP
IDDLRHHKAIAADGSFNIKVLPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHA
LDVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGALRNNNSRMFNLVGPDIGFDS
INDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIGTMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL
>Mature_468_residues
SQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHYKWRAMRTNGVAERLCTGDASD
REKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDPI
DDLRHHKAIAADGSFNIKVLPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHAL
DVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGALRNNNSRMFNLVGPDIGFDSI
NDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIGTMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQLG
LLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=469, Percent_Identity=83.1556503198294, Blast_Score=832, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 53475; Mature: 53344

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHY
CCCHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCEEEEEEECCCE
KWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDPIDDLRHHKAIAADGSFNIKV
CCCHHHHHHCCCHHHHCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHEEECCCCEEEEE
LPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHA
CCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGA
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHH
LRNNNSRMFNLVGPDIGFDSINDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIG
EECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
TMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
SQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHY
CCHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCEEEEEEECCCE
KWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLS
EEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCCCCCCCCC
PATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDPIDDLRHHKAIAADGSFNIKV
CCCHHHHHHCCCHHHHCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHEEECCCCEEEEE
LPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHA
CCCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LDVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGA
EEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHH
LRNNNSRMFNLVGPDIGFDSINDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIG
EECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
TMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYT
HHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA