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The map label for this gene is aaeA [H]

Identifier: 170022735

GI number: 170022735

Start: 536098

End: 537033

Strand: Direct

Name: aaeA [H]

Synonym: YPK_0484

Alternate gene names: 170022735

Gene position: 536098-537033 (Clockwise)

Preceding gene: 170022734

Following gene: 170022736

Centisome position: 11.43

GC content: 52.78

Gene sequence:

>936_bases
GTGAGTACATTTTCATTAAAAATAATCCGCGTTGGCATCACCGTCTTGGTGGTCGTACTGGCTGTTATCGCGATTTTCAA
CGTGTGGGCCTTCTATACTGAATCGCCGTGGACCCGTGATGCTAAATTTACCGCAGACGTGGTCGCTATCGCACCGGATG
TCAGCGGCTTACTGACCGAAGTACCGGTAAAAGACAACCAACTGGTGCAGAAAGGCCAGATTCTGTTTGTCATTGATCAA
CCCCGTTATCAGCAGGCGTTGGCTGAAGCCGAGGCCGATGTGGCCTATTACCAGACCCTGGCTGCGGAGAAGCAACGGGA
GTCCAGTAGGCGTCATCGCCTGGGTATTCAGGCGCTGTCACAAGAAGAGATTGACCAGGCAAGCAATGTGTTGCAAACCG
TCCAGCATCAGTTGGCAAAAGCCATTGCCGTGCGGGATTTAGCCCGCCTTGATCTGGAAAGGACCACGGTACGTGCACCA
GCAGAAGGGTGGGTGACCAACCTGAATGTACATGCTGGCGAGTTTATTAACCGTGGGGCCACGGCAGTCGCATTGGTGAA
AAAAGATACTTTCTACATTTTAGCCTATCTGGAGGAGACGAAGCTCGAAGGGGTTAAACCGGGCTACCGAGCGGAAATTA
CCCCGCTGGGCAGTAACCGCATCCTGCATGGTACGGTCGATAGCATTTCAGCCGGTGTTACCAATAGCAGTAGCAGTGCC
GACAGCAAAGGGCTGGCGACCATTGATAATAATCTTGAATGGGTACGCTTGGCGCAACGGGTACCGGTGAAGATTCATCT
GGATAGCGAAGACCAGCAATATTTGTATCCGGCGGGCACCACGGCCACGGTGGTGATCACCGGGCCGAATGATCGTGATC
CTCATCAGGTATCGCCCATGACCAAGTTGATGCATCGTCTACGTGAGTTTGGCTAA

Upstream 100 bases:

>100_bases
ACCGGTATTTACGAGTTTGTTTGGCACCCGGCTCTTTTTAATACGGCGCTGTATTGTTGCCTGTTTTATTTAACATCCCG
TCTTTTTTCCTGAGGTCACA

Downstream 100 bases:

>100_bases
TATGACCCACCCAAGCTTTATTCGCCTGCGGTTTGCGTTCAAGCTGAGTTTTGCCATTGTGGCGGCATTATTTCTTGGCT
TTCATCTGCAATTGGAAACA

Product: p-hydroxybenzoic acid efflux subunit AaeA

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQ
PRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAP
AEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQVSPMTKLMHRLREFG

Sequences:

>Translated_311_residues
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQ
PRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAP
AEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQVSPMTKLMHRLREFG
>Mature_310_residues
STFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQP
RYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPA
EGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSAD
SKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQVSPMTKLMHRLREFG

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789637, Length=311, Percent_Identity=72.6688102893891, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI87081951, Length=283, Percent_Identity=38.5159010600707, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1790519, Length=311, Percent_Identity=29.2604501607717, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788711, Length=309, Percent_Identity=25.2427184466019, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34344; Mature: 34212

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHEE
VPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALS
CCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPAEGWVTNLNVHAGEFINRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEHHHHHHCCC
TAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
EEEEEEECCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCEEEECHHHHHCCCCCCCCCC
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQVSPM
CCCCCEEECCCHHHHHHHHHCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCCCCHH
TKLMHRLREFG
HHHHHHHHHCC
>Mature Secondary Structure 
STFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTE
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHEE
VPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALS
CCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPAEGWVTNLNVHAGEFINRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEHHHHHHCCC
TAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSA
EEEEEEECCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCEEEECHHHHHCCCCCCCCCC
DSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQVSPM
CCCCCEEECCCHHHHHHHHHCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCCCCCCHH
TKLMHRLREFG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA