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The map label for this gene is fur [H]

Identifier: 169629557

GI number: 169629557

Start: 2524747

End: 2525205

Strand: Reverse

Name: fur [H]

Synonym: MAB_2471c

Alternate gene names: 169629557

Gene position: 2525205-2524747 (Counterclockwise)

Preceding gene: 169629558

Following gene: 169629556

Centisome position: 49.83

GC content: 64.49

Gene sequence:

>459_bases
ATGGCCTTCACATCGGATGAGTACGCGGCGCTGCTGCGCACGGCCGATCTGCGCGTGACCCGGCCCCGGGTCGCCGTGCT
GGAAGCCGTGGAAGCGAACCCGCATGCCGATACCGAAACTGTTTTCGGTGTCGTCAGGACCGGGCTGCCCGAGGTGTCCC
GCCAAGCCGTTTACGACGTGTTGGCTGCGCTGACCTCGGCGGGCCTGATACGCAAAATTCAGCCTTCCGGCTCCGTCGCA
CGCTATGAATCGCGGGTCGGCGACAACCATCACCACGTCGTATGCCGCTCCTGCGGCGCTATCGCCGACGTCGACTGCGC
CGTAGGCGCCGCGCCATGCTTGACACCGTCGGACTACAACGGCTTCATCCTCGAAGAGGCCGAGGTCATCTACTGGGGTC
TGTGCCCCGATTGCGCTTCCACGGAAGCGGCACCACGAATTTCGGGATCACACACGTGA

Upstream 100 bases:

>100_bases
TCTACCGGTGATGTGACGCTGGTCAGGACCCTTTCGGAATCCCGCCGTCTGTTTTTCGCATTTCCTGGATTGATTCCAGA
TAATTGGGCATACTGGCCTC

Downstream 100 bases:

>100_bases
TCACAGCCCACATCACCCCCTCCCGAAAGGAATGTTGTGTCTGAAGAACACCCGCCTATTGCAGAGGCGAACAGCCAACC
CTCAAACGGTTGCCCCGTCG

Product: ferric uptake regulation protein FurA

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MAFTSDEYAALLRTADLRVTRPRVAVLEAVEANPHADTETVFGVVRTGLPEVSRQAVYDVLAALTSAGLIRKIQPSGSVA
RYESRVGDNHHHVVCRSCGAIADVDCAVGAAPCLTPSDYNGFILEEAEVIYWGLCPDCASTEAAPRISGSHT

Sequences:

>Translated_152_residues
MAFTSDEYAALLRTADLRVTRPRVAVLEAVEANPHADTETVFGVVRTGLPEVSRQAVYDVLAALTSAGLIRKIQPSGSVA
RYESRVGDNHHHVVCRSCGAIADVDCAVGAAPCLTPSDYNGFILEEAEVIYWGLCPDCASTEAAPRISGSHT
>Mature_151_residues
AFTSDEYAALLRTADLRVTRPRVAVLEAVEANPHADTETVFGVVRTGLPEVSRQAVYDVLAALTSAGLIRKIQPSGSVAR
YESRVGDNHHHVVCRSCGAIADVDCAVGAAPCLTPSDYNGFILEEAEVIYWGLCPDCASTEAAPRISGSHT

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16158; Mature: 16027

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTSDEYAALLRTADLRVTRPRVAVLEAVEANPHADTETVFGVVRTGLPEVSRQAVYDV
CCCCCHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
LAALTSAGLIRKIQPSGSVARYESRVGDNHHHVVCRSCGAIADVDCAVGAAPCLTPSDYN
HHHHHHHHHEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCC
GFILEEAEVIYWGLCPDCASTEAAPRISGSHT
CEEEECCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AFTSDEYAALLRTADLRVTRPRVAVLEAVEANPHADTETVFGVVRTGLPEVSRQAVYDV
CCCCHHHHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHH
LAALTSAGLIRKIQPSGSVARYESRVGDNHHHVVCRSCGAIADVDCAVGAAPCLTPSDYN
HHHHHHHHHEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCC
GFILEEAEVIYWGLCPDCASTEAAPRISGSHT
CEEEECCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]