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The map label for this gene is uxuR [H]

Identifier: 169629358

GI number: 169629358

Start: 2318739

End: 2319452

Strand: Reverse

Name: uxuR [H]

Synonym: MAB_2272c

Alternate gene names: 169629358

Gene position: 2319452-2318739 (Counterclockwise)

Preceding gene: 169629360

Following gene: 169629357

Centisome position: 45.77

GC content: 64.15

Gene sequence:

>714_bases
ATGCAGCCGGTCCGTCGCCAAACATTGATTGGCCAGGTCACCGAGCAACTCCGGGAGGAGATTGTGTCGGGACGCTGGGC
TATCGGGGCACGCATCCCTACCGAACCGGAATTGTGCGAGCTCACTGGAACTTCCCGCAACACCATTAGAGAAGCGGTCC
AGGCCCTGGTCCACGCGGGCATGCTCGAACGACGCCAGGGCTCGGGCACCTACGTGCTCTCCCTGGGTGGCAGCTCGGCC
ATCGCCGACTACTTCGCCGCCGCCAACAACCGCGACCTGATCGAATTGCGGCAGACCCTCGAAGTGACCGCGGCCGGGCT
GGCCGCCCAGCGGCGTGACGAAGATGACATCGAGCAGCTGCGCGCACTGTTGGTACGCCGCAACGAACTTTGGGCGCCAC
ACCATGTCGAGCCGCACAACGTCGAGGAAGCCATCTCCACCGACATCGCGGTACACCGGGCCGTGGTAGCCGCCAGTCAC
AACGCCCTCTACCTGGAACTTTACGACTCGCTGCTGGGACTGATGGACCACTACATGCGCGGTAACCCCATCGGCGCGGA
ATGTTCATTCGAACACGAGCACACCAGGCTCGTCGAGAGCGTCATCGCCGGCGATATCGGGGGTGCCACATCCGCCACGG
AGCAGCTCTTCGCCGAGCTGAGGCTGAGCCGCGATCAGCCCGGGCGGAACTTTCCCCACCATCCACACGACTAG

Upstream 100 bases:

>100_bases
CGGTCACCGTTCATCCTCCTCAAATACAGCCCGGCAAATCATAGGATGAATGGATGAATGCGTTCAAGCTGATTTCCGAC
GCACGCTACGATGAGCCGTC

Downstream 100 bases:

>100_bases
CTGAACGTGAAGATCGTCATCCCGGCAGCAGTCGCGCTGTCATTGCTCGCCGGTTGTTCGGCGCATGAGTCCACCCCCGC
CGAGCAGGCAGCGACGGTAA

Product: putative transcriptional regulator, GntR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAGMLERRQGSGTYVLSLGGSSA
IADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASH
NALYLELYDSLLGLMDHYMRGNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRNFPHHPHD

Sequences:

>Translated_237_residues
MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAGMLERRQGSGTYVLSLGGSSA
IADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASH
NALYLELYDSLLGLMDHYMRGNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRNFPHHPHD
>Mature_237_residues
MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAGMLERRQGSGTYVLSLGGSSA
IADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASH
NALYLELYDSLLGLMDHYMRGNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRNFPHHPHD

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=162, Percent_Identity=32.7160493827161, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786303, Length=231, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26276; Mature: 26276

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAG
CCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
MLERRQGSGTYVLSLGGSSAIADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQL
HHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYMR
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRNFPHHPHD
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAG
CCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
MLERRQGSGTYVLSLGGSSAIADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQL
HHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYMR
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRNFPHHPHD
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]