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The map label for this gene is bcp [C]

Identifier: 169629332

GI number: 169629332

Start: 2273405

End: 2274352

Strand: Direct

Name: bcp [C]

Synonym: MAB_2246

Alternate gene names: 169629332

Gene position: 2273405-2274352 (Clockwise)

Preceding gene: 169629331

Following gene: 169629334

Centisome position: 44.87

GC content: 63.92

Gene sequence:

>948_bases
ATGCAGATTTCCGAGCTGGCCCGCCGGGCGGGTGTATCGCTGAAGGCCGTGCGCTACTACGAGCGCCTCGGTCTGGTGAT
GCCGTCGCGCCTGGGCAATGGGTATCGGGACTATACCGATGATGACCTACAGATAGTCGGTGAGATCCGATCGCTTGCCG
CGGCTGGAATTTCGCCCTCGCTGGCGCGTCCGTTCATCGAGTGCCTGCGCGAGGGCCATGACCACAGCGATGACTGTCCG
TCGGCGCTCGCCGCATATCGGGACAGCATCGCGGCTCTGGACCAGAGCATCGCTTCATTGATCATGCGCCGTCGGATCCT
CGCGGCGCGGCTGGATGCGGCCGCGGCGAGAACCTTCACCGAGGAGCCCCGAAACATGGATGATTACACCGAACTTCCCT
TCGGCCTGCCGGTGCCGGTCGATGATGGCGCCGCCGACCACCTGCAAGACCGGCCTCTGCCGGACCTGACCTTGATGGCA
ACTGGCGGGTGTGCGGTCCGGCTACGCGGGCTACCCGAGGGGCGCACAGTGTTGTATCTGTACCCACTGACGGGCCGTCC
CGGCCTCGACATCCCAGAGGGCTGGGACGCCATACCGGGGGCACGCGGCTGCACCACCGAGGCGTGCGGCTTTCGCGATC
ATTTCGATGAACTGCGCGCGGCTGGCGCACAACAGGTTTGGGGACTATCGAGCCAAGATACCGACTACCAGGCGGAGGTT
GTCCGACGGCTCAGGCTGCCGTTCCACATGCTTTCGGATCCGGACTTCACACTGGCAGAGGCACTGCACCTGCCCACGTT
CGCCGCCGTCGGACACCCGCGTCTTTACGCGCGGATCACACTTGTTGTCCGAGACGGGCGCATTGAGCAGGTCTTTTATC
CGATCTTTCCGCCGGATACACATGCCCAGCAGGTGCTTGAGTGGTTGACATCGCACCCGATGGATTGA

Upstream 100 bases:

>100_bases
GCGAGGCATAGCTCTTCGCGACTGACTATCCGCGCCGCCGCCTCGCCCGGATTGACCCTACCCCTGAGGGCAGGGTCTAC
GGTCCCGGTGAGGATTAAGC

Downstream 100 bases:

>100_bases
CGGCCTAGCCCGTCAGGGAGGCCAGCAGCGCTCGCTTGTCGATCTTGCCCACAGCGGTCAGTGGCAGTGCGGAAACGGCG
ACCAGTTTGTCGACGCGTGA

Product: thiol-specific antioxidant related protein/peroxidoxin BcpB

Products: Acceptor; H2O; oxidized thioredoxin [C]

Alternate protein names: BcpB Protein; Redoxin Domain-Containing Protein; Redoxin; Peroxiredoxin; Transcriptional Regulator MerR Family; Cu(I)-Responsive Transcriptional Regulator; Thiol-Specific Antioxidant Related Protein; MerR-Family Transcriptional Regulator; HxlR Family Transcriptional Regulator; Redoxin Domain Protein; Antioxidant; Transcriptional Regulator; Regulatory Protein MerR; Thiol-Specific Antioxidant Related Protein/Peroxidoxin BcpB; Thioredoxin Peroxidase Family Protein; Redoxin Superfamily; Bacterioferritin Comigratory Protein; Bacterioferritin Comigratory Protein BcpB; Peroxiredoxin Family

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQISELARRAGVSLKAVRYYERLGLVMPSRLGNGYRDYTDDDLQIVGEIRSLAAAGISPSLARPFIECLREGHDHSDDCP
SALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFTEEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMA
TGGCAVRLRGLPEGRTVLYLYPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSSQDTDYQAEV
VRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITLVVRDGRIEQVFYPIFPPDTHAQQVLEWLTSHPMD

Sequences:

>Translated_315_residues
MQISELARRAGVSLKAVRYYERLGLVMPSRLGNGYRDYTDDDLQIVGEIRSLAAAGISPSLARPFIECLREGHDHSDDCP
SALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFTEEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMA
TGGCAVRLRGLPEGRTVLYLYPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSSQDTDYQAEV
VRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITLVVRDGRIEQVFYPIFPPDTHAQQVLEWLTSHPMD
>Mature_315_residues
MQISELARRAGVSLKAVRYYERLGLVMPSRLGNGYRDYTDDDLQIVGEIRSLAAAGISPSLARPFIECLREGHDHSDDCP
SALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFTEEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMA
TGGCAVRLRGLPEGRTVLYLYPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSSQDTDYQAEV
VRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITLVVRDGRIEQVFYPIFPPDTHAQQVLEWLTSHPMD

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788825, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34907; Mature: 34907

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISELARRAGVSLKAVRYYERLGLVMPSRLGNGYRDYTDDDLQIVGEIRSLAAAGISPS
CCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
LARPFIECLREGHDHSDDCPSALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFT
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMATGGCAVRLRGLPEGRTVLYL
CCCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEEEEEECCCCCCEEEEE
YPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSSQDTDYQAEV
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCHHHHH
VRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITLVVRDGRIEQVFYPIFPPDT
HHHHHCCHHHCCCCCHHHHHHHHCCHHHHCCCCEEEEEEEEEEECCCEEEEEEECCCCCH
HAQQVLEWLTSHPMD
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MQISELARRAGVSLKAVRYYERLGLVMPSRLGNGYRDYTDDDLQIVGEIRSLAAAGISPS
CCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
LARPFIECLREGHDHSDDCPSALAAYRDSIAALDQSIASLIMRRRILAARLDAAAARTFT
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEPRNMDDYTELPFGLPVPVDDGAADHLQDRPLPDLTLMATGGCAVRLRGLPEGRTVLYL
CCCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEEEEEECCCCCCEEEEE
YPLTGRPGLDIPEGWDAIPGARGCTTEACGFRDHFDELRAAGAQQVWGLSSQDTDYQAEV
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCCCHHHHH
VRRLRLPFHMLSDPDFTLAEALHLPTFAAVGHPRLYARITLVVRDGRIEQVFYPIFPPDT
HHHHHCCHHHCCCCCHHHHHHHHCCHHHHCCCCEEEEEEEEEEECCCEEEEEEECCCCCH
HAQQVLEWLTSHPMD
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced acceptor; H2O2; reduced thioredoxin [C]

Specific reaction: reduced acceptor + H2O2 = Acceptor + H2O reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: Oxidoreductases; Acting on a peroxide as acceptor; Peroxidase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA