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The map label for this gene is pat [H]

Identifier: 169629254

GI number: 169629254

Start: 2182837

End: 2183895

Strand: Direct

Name: pat [H]

Synonym: MAB_2168

Alternate gene names: 169629254

Gene position: 2182837-2183895 (Clockwise)

Preceding gene: 169629253

Following gene: 169629256

Centisome position: 43.08

GC content: 62.51

Gene sequence:

>1059_bases
ATGGGGAGGGAGGGGCCAGTGACAGTGAGCCCGCTGCGGTTGGCGTTGAACGAGAACCCCTATCGTCCACTGCCGTCGGT
GCGTGACGCGCTCAGGCACGACCTCGCCGAGGTGAACCGCTATCCCGAATTCTTGCCGGTGGTGTTGCCGCGGCTGATCG
CGGATCGCGTGGGGATGACGCCGGAGGAAGTGGTGGTGGGCGTAGGTGCCACTGGGGTTGCACTGCAGGTGCTGCAGGCG
TTGTGCAAGCCGGGTGACTCGCTCGTCTTCGCGCACCCGACGTTCGACGGCTACCCGATACTGGCCGATATCGCCGGGCT
CATTCAGGTTCCGATTCCGTTGGCGGACAACGGTATGACCGACCTCGACGAACTGCTGGGAGCCGCTTATGACGCCGATG
ACGCAGCATTGGTACTGTGCCGGCCGCATAATCCGACGGGAACACTGATACCGGCCGACCAGGTCTATGAGTTTGTCCGT
CAGGCGCCGCCCACCAGCGTGGTGGTTCTGGACGAGGCGTATATCGAATTCGTGGATCCCGACGAGCATCTCGATATTCC
CGGACTGCTGCGGTTGCACCCGAACCTGGTTGTGTTGCGCACCTTCTCAAAGGCGTATGGGTTGGCCGGACTGCGCATCG
GGTATGGGCTGGCCGCGCCCGCGGTCTGCGGTGTCATTCGTCGATACCAACTCCCGTTCGGTATGAATCGCGCGGCCGCG
GTAGCGGTTGCCGCATCGTATGCGGCGGAAGGTGAACTGCGAGTACGTGTTGATTCGATTGTCTACGAACGTGATCGGCT
CCGCGCTCGACTGGCTCAGATGGGTGCGCACATCCCCGAGTCTCATGCCAACTTCGTGTACCTACCGGCACGCGGTGACG
GTGAACGTTGGATGTCGATCCTGGGAACCGGCGATGTGGTGGCCAAAGAATATTCCGATGGCGGTGTGCGGCTCACCGTT
GGCGATCCGCGCGAGATGGCGATAGTCGCGCGGCGGCTGTTGGAGGTGGACGAGATTGGTGAAAGCGCAGTGTCCCGGAT
GAGCAGACCTGCGTCATAG

Upstream 100 bases:

>100_bases
TCGATAAGGCGATCGCCGAACGGCAGGTGCGCCCGGGTGACGCCGTGATGCTGGCCGGATTCGCCCATGCCGGCGACTAC
GCGGCCGCGGCGGCGGTGCG

Downstream 100 bases:

>100_bases
ACAGGTTGGCCGCGGCGATCCGTCCCCCCGATTGCCGACCCCGAAACGGCAAGGACCGTCGCGGTCAACCCTCCCTCCTC
AAAATGCGTAGCGGTGGTAT

Product: putative aminotransferase

Products: 2-Oxoglutarate; L-Histidinol phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGREGPVTVSPLRLALNENPYRPLPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVGMTPEEVVVGVGATGVALQVLQA
LCKPGDSLVFAHPTFDGYPILADIAGLIQVPIPLADNGMTDLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVR
QAPPTSVVVLDEAYIEFVDPDEHLDIPGLLRLHPNLVVLRTFSKAYGLAGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAA
VAVAASYAAEGELRVRVDSIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSILGTGDVVAKEYSDGGVRLTV
GDPREMAIVARRLLEVDEIGESAVSRMSRPAS

Sequences:

>Translated_352_residues
MGREGPVTVSPLRLALNENPYRPLPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVGMTPEEVVVGVGATGVALQVLQA
LCKPGDSLVFAHPTFDGYPILADIAGLIQVPIPLADNGMTDLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVR
QAPPTSVVVLDEAYIEFVDPDEHLDIPGLLRLHPNLVVLRTFSKAYGLAGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAA
VAVAASYAAEGELRVRVDSIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSILGTGDVVAKEYSDGGVRLTV
GDPREMAIVARRLLEVDEIGESAVSRMSRPAS
>Mature_351_residues
GREGPVTVSPLRLALNENPYRPLPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVGMTPEEVVVGVGATGVALQVLQAL
CKPGDSLVFAHPTFDGYPILADIAGLIQVPIPLADNGMTDLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVRQ
APPTSVVVLDEAYIEFVDPDEHLDIPGLLRLHPNLVVLRTFSKAYGLAGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAAV
AVAASYAAEGELRVRVDSIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSILGTGDVVAKEYSDGGVRLTVG
DPREMAIVARRLLEVDEIGESAVSRMSRPAS

Specific function: May catalyze the transamination reaction in phenylalanine biosynthesis [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=299, Percent_Identity=31.1036789297659, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=215, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.9 [C]

Molecular weight: Translated: 38069; Mature: 37938

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGREGPVTVSPLRLALNENPYRPLPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVGMT
CCCCCCEEEHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
PEEVVVGVGATGVALQVLQALCKPGDSLVFAHPTFDGYPILADIAGLIQVPIPLADNGMT
HHHEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCH
DLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVRQAPPTSVVVLDEAYIEFVDP
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHEEEEECC
DEHLDIPGLLRLHPNLVVLRTFSKAYGLAGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAA
CCCCCCCCEEEECCCEEEEEEHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHH
VAVAASYAAEGELRVRVDSIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSI
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHH
LGTGDVVAKEYSDGGVRLTVGDPREMAIVARRLLEVDEIGESAVSRMSRPAS
HCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GREGPVTVSPLRLALNENPYRPLPSVRDALRHDLAEVNRYPEFLPVVLPRLIADRVGMT
CCCCCEEEHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
PEEVVVGVGATGVALQVLQALCKPGDSLVFAHPTFDGYPILADIAGLIQVPIPLADNGMT
HHHEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCH
DLDELLGAAYDADDAALVLCRPHNPTGTLIPADQVYEFVRQAPPTSVVVLDEAYIEFVDP
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHEEEEECC
DEHLDIPGLLRLHPNLVVLRTFSKAYGLAGLRIGYGLAAPAVCGVIRRYQLPFGMNRAAA
CCCCCCCCEEEECCCEEEEEEHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCHHHH
VAVAASYAAEGELRVRVDSIVYERDRLRARLAQMGAHIPESHANFVYLPARGDGERWMSI
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHH
LGTGDVVAKEYSDGGVRLTVGDPREMAIVARRLLEVDEIGESAVSRMSRPAS
HCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-Glutamate; 3-(Imidazol-4-yl)-2-oxopropyl phosphate [C]

Specific reaction: L-Glutamate + 3-(Imidazol-4-yl)-2-oxopropyl phosphate --> 2-Oxoglutarate + L-Histidinol phosphate [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA