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The map label for this gene is tldD [C]

Identifier: 169628808

GI number: 169628808

Start: 1748067

End: 1749584

Strand: Direct

Name: tldD [C]

Synonym: MAB_1718

Alternate gene names: 169628808

Gene position: 1748067-1749584 (Clockwise)

Preceding gene: 169628804

Following gene: 169628809

Centisome position: 34.5

GC content: 67.39

Gene sequence:

>1518_bases
GTGACACGGTCAGTAGATCCCGATTTCCTGGCGCTGCCCCGCGCCGAGCTCGCCGACGCCGCCCTGAACGCGGCCCGCGC
CGCCGGTGCCAGTTATGCGGACCTGCGCATCCATCGGTTGATCAACGAGGAGCTGATGCTGCGCGACGAGCAGGTGGAGA
CCGCCGTCTCCGGGCGCACCATCGGTTTGGCGGTGCGGGTGATTGTCGACGGCACCTGGGGATTCGCCTCGCATGTGCAG
CTGGATACGACGGCCGCCGCCGAGACCGCGCGCCGGGCCGTGGCGGTGGCCCGCGGGCTGCGCAGCCTGAACCGTGAGCG
CGTCGAGCTGGCCGACGAACCGGTCTACGCCGATGTGCAGTGGGTGTCCGACTACGCGATCGACCCGTTCGGGGTGCCGC
AGGCCGACAAGATCGCGGTGCTGCAAGAGTATTCGGCGCGGCTGCTGGCCTCCGATGGCGTGGACCACGCCTCGGCATCG
CTGACGGCGGTCAAGGAGCAGACCTTTTACGCCGACACCTTCGGCTCGTCCATCACCCAACAGCGGGTGCGGGTGATGTC
GCAGCTGGACGCCATCGCCGTCGACGCAGCCACCGGATCATTTGAGACCATGCGCACGCTGGCTCCGCCGATGGGCCGCG
GCTGGGAGGCCGTCGGCGGTGACGGGGTGTGGGACTGGAGCGCCGAGCTGCGCGAGATCCCGGAGCTGCTCACCGAGAAG
GTGAAGGCGCCCAGCGTGGTCGCCGGCCCCACCGACCTGGTGATCGATCCGACCAACCTGTGGCTCACCATTCACGAATC
CATCGGTCACGCCACCGAATACGACAGGGCCATCGGCTATGAGGCCGCCTATGCCGGGACCTCGTTCGCGACCCCCGACA
AGCTGGGCGCCATGAAGTACGGCTCGCCGGTCATGAACGTGACCGCCGACCGCAACGAGGTGCACGGCCTGGCCTCGGTC
GGATACGACGACGAGGGGGTGGCCTCGCAGCGCTGGGACCTGGTGCGCGACGGCATCTTCGTCGGTTATCAGCTGGATCG
GGTGTTCGCGCCGCGGTTGGGCCAGGAGCGTTCCAACGGCTGCTCGTATGCCGACTCGCCGCATCACGTGCCGATCCAGC
GGATGGCCAATGTGTCGCTACAGGCCTCCCCGGAGGAGCGCAGCACCGACGATCTGATCTCCGGGGTGGAAGACGGCATC
TACATCGTCGGTGACAAGTCGTGGTCAATCGACATGCAGCGCTACAACTTCCAGTTCACCGGGCAGCGGTTCTACCGCAT
CCGTGGCGGCAAGCTGGACGGGCAGCTGCGCGATGTCGCCTACCAGGCCACCACCACCGACTTCTGGGGTTCCATGGAAG
CCGTTGGTGGACAATCGACATGGCGCCTGGGCGGTGCCTTCAACTGCGGTAAGGCCCAGCCCGGCCAGGTCGCGGCGGTC
AGCCACGGCTGCCCGTCGGCGCTGTTCCGTGGCGTCAATGTTCTCAACACCAAAGAAGAGGGCGGTAGCAGCCGATGA

Upstream 100 bases:

>100_bases
GACGGCTGTCTGCCGCGACCGACTCACGGGACCATTAAATCGCCGATGAGCCGCTTGCGCGAAGAGCGGGTGCCTGGACA
TCCCCGGTAGCGTTGGGCAC

Downstream 100 bases:

>100_bases
GCCGCTTGCGCGAAGAGGAGACGGCACAGTGATTCCCGCACAGCAGGTCGCCGACGATGTCCTGGCCGAGGCCGCACGAC
GCGGCGGTGCTGACGACACC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLRDEQVETAVSGRTIGLAVRVIVDGTWGFASHVQ
LDTTAAAETARRAVAVARGLRSLNRERVELADEPVYADVQWVSDYAIDPFGVPQADKIAVLQEYSARLLASDGVDHASAS
LTAVKEQTFYADTFGSSITQQRVRVMSQLDAIAVDAATGSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEK
VKAPSVVAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAMKYGSPVMNVTADRNEVHGLASV
GYDDEGVASQRWDLVRDGIFVGYQLDRVFAPRLGQERSNGCSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVEDGI
YIVGDKSWSIDMQRYNFQFTGQRFYRIRGGKLDGQLRDVAYQATTTDFWGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAV
SHGCPSALFRGVNVLNTKEEGGSSR

Sequences:

>Translated_505_residues
MTRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLRDEQVETAVSGRTIGLAVRVIVDGTWGFASHVQ
LDTTAAAETARRAVAVARGLRSLNRERVELADEPVYADVQWVSDYAIDPFGVPQADKIAVLQEYSARLLASDGVDHASAS
LTAVKEQTFYADTFGSSITQQRVRVMSQLDAIAVDAATGSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEK
VKAPSVVAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAMKYGSPVMNVTADRNEVHGLASV
GYDDEGVASQRWDLVRDGIFVGYQLDRVFAPRLGQERSNGCSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVEDGI
YIVGDKSWSIDMQRYNFQFTGQRFYRIRGGKLDGQLRDVAYQATTTDFWGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAV
SHGCPSALFRGVNVLNTKEEGGSSR
>Mature_504_residues
TRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLRDEQVETAVSGRTIGLAVRVIVDGTWGFASHVQL
DTTAAAETARRAVAVARGLRSLNRERVELADEPVYADVQWVSDYAIDPFGVPQADKIAVLQEYSARLLASDGVDHASASL
TAVKEQTFYADTFGSSITQQRVRVMSQLDAIAVDAATGSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEKV
KAPSVVAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAMKYGSPVMNVTADRNEVHGLASVG
YDDEGVASQRWDLVRDGIFVGYQLDRVFAPRLGQERSNGCSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVEDGIY
IVGDKSWSIDMQRYNFQFTGQRFYRIRGGKLDGQLRDVAYQATTTDFWGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAVS
HGCPSALFRGVNVLNTKEEGGSSR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=460, Percent_Identity=23.0434782608696, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 54748; Mature: 54616

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLRDEQVETAVSGRT
CCCCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IGLAVRVIVDGTWGFASHVQLDTTAAAETARRAVAVARGLRSLNRERVELADEPVYADVQ
EEEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEE
WVSDYAIDPFGVPQADKIAVLQEYSARLLASDGVDHASASLTAVKEQTFYADTFGSSITQ
EHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEHHHHCCHHHH
QRVRVMSQLDAIAVDAATGSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEK
HHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHH
VKAPSVVAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAMKY
CCCCCEEECCCCEEECCCCEEEEEEHHCCCHHHHHHHCCCHHHCCCCCCCCCHHHCCCCC
GSPVMNVTADRNEVHGLASVGYDDEGVASQRWDLVRDGIFVGYQLDRVFAPRLGQERSNG
CCCCEEEECCCHHHCCHHCCCCCCCCCCHHHHHHHHCCEEEEEEEHHHHHCCCCCCCCCC
CSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVEDGIYIVGDKSWSIDMQRYNFQFT
CCCCCCCCCCCHHHHCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCEEEEEEEEEEEEC
GQRFYRIRGGKLDGQLRDVAYQATTTDFWGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAV
CCEEEEEECCCCCCHHHHHEEEEECHHHCCCHHHCCCCCEEEECCCCCCCCCCCCCEEEE
SHGCPSALFRGVNVLNTKEEGGSSR
CCCCHHHHHCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TRSVDPDFLALPRAELADAALNAARAAGASYADLRIHRLINEELMLRDEQVETAVSGRT
CCCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IGLAVRVIVDGTWGFASHVQLDTTAAAETARRAVAVARGLRSLNRERVELADEPVYADVQ
EEEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEE
WVSDYAIDPFGVPQADKIAVLQEYSARLLASDGVDHASASLTAVKEQTFYADTFGSSITQ
EHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEHHHHCCHHHH
QRVRVMSQLDAIAVDAATGSFETMRTLAPPMGRGWEAVGGDGVWDWSAELREIPELLTEK
HHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHH
VKAPSVVAGPTDLVIDPTNLWLTIHESIGHATEYDRAIGYEAAYAGTSFATPDKLGAMKY
CCCCCEEECCCCEEECCCCEEEEEEHHCCCHHHHHHHCCCHHHCCCCCCCCCHHHCCCCC
GSPVMNVTADRNEVHGLASVGYDDEGVASQRWDLVRDGIFVGYQLDRVFAPRLGQERSNG
CCCCEEEECCCHHHCCHHCCCCCCCCCCHHHHHHHHCCEEEEEEEHHHHHCCCCCCCCCC
CSYADSPHHVPIQRMANVSLQASPEERSTDDLISGVEDGIYIVGDKSWSIDMQRYNFQFT
CCCCCCCCCCCHHHHCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCEEEEEEEEEEEEC
GQRFYRIRGGKLDGQLRDVAYQATTTDFWGSMEAVGGQSTWRLGGAFNCGKAQPGQVAAV
CCEEEEEECCCCCCHHHHHEEEEECHHHCCCHHHCCCCCEEEECCCCCCCCCCCCCEEEE
SHGCPSALFRGVNVLNTKEEGGSSR
CCCCHHHHHCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]