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The map label for this gene is glyQS [H]

Identifier: 169628792

GI number: 169628792

Start: 1728946

End: 1730364

Strand: Direct

Name: glyQS [H]

Synonym: MAB_1702

Alternate gene names: 169628792

Gene position: 1728946-1730364 (Clockwise)

Preceding gene: 169628791

Following gene: 169628793

Centisome position: 34.12

GC content: 63.28

Gene sequence:

>1419_bases
GTGGCCGCCAAGCCGAACGCCGCTGGTAAGAAGATCGAGGCCGTCGTCAACCTCGCCAAACGCCGGGGACTTGTGTACCC
CTGCGGCGAGATCTACGGCGGAACCAAGTCGGCGTGGGATTACGGGCCGCTCGGCGTGGAACTCAAGGAGAACATCAAGA
AGCAGTGGTGGCGCTCGGTCGTCACCAGCCGCGACGACGTCGTCGGCCTGGACTCCTCGGTGATCCTGCCGCGCCAGGTG
TGGGTGGCCTCCGGCCACGTCGAGGTGTTCAACGATCCGCTGGTGGAGTGCCTGAACTGTCATAAGCGCCACCGCCAGGA
CCACCTGCAAGAAGCCTATAGCGAAAAAGAGGCGAAAAAGGGCCTCACAATCGCGCCCGAGTCGGTTCCCATGACCGAGA
TCGTGTGCCCGGACTGTGGCAACAAGGGCCAGTGGACCGAGCCGCGCGACTTCAACATGATGCTCAAGACCTACCTGGGT
CCCATCGAGACCGAAGAGGGTCTGCACTACCTGCGCCCCGAGACGGCACAGGGCATCTTCATCAACTTCAAGAATGTCGT
GACCACCTCGCGGCAGAAGCCGCCCTTCGGCATCGGCCAGATCGGCAAGAGCTTCCGCAACGAGATCACCCCCGGCAACT
TCATCTTCCGCACGCGCGAATTCGAGCAGATGGAGATGGAGTTCTTCGTCGAGCCGTCCACGGCGCCCGAGTGGCACAAG
TACTGGATCGACACCCGGCTGCAGTGGTACGTCGACCTGGGTATCGACCCGGAGAATCTGCGGCTGTACGACCACCCCAA
GGAGAAGTTGTCGCATTACTCCGACGGCACCGTCGATATCGAGTACAAGTTCGGTTTCAGCGGCAACCCGTGGGGCGAGC
TGGAAGGCATCGCCAACCGCACCGACTTCGATTTATCCACGCACGCAAAGCATTCCGGTGAGGATCTGTCGTACTACGAT
CAGGCCGAGGACCGCCGGTACACCCCGTACGTGATTGAGCCGGCGGCCGGTCTGACCCGGTCCTTCATGGCCTTCCTGGT
TGATGCGTACCACGAGGACGAGGCGCCGAACGCCAAGGGCGGCGTGGACACCCGTACGGTGCTGCGGCTGGATCCGCGGC
TGGCCCCGGTCAAGGTCGCGGTACTGCCGCTGTCGCGCAATGCCGACCTGAGCCCGCGGGCCAAGGCGCTGGCCGCCGAG
CTGCGCCAGAGCTGGAATGTCGACTTCGATGACGCCGGGGCAATCGGCCGGAGGTATCGTCGACAGGACGAGATCGGTAC
CCCGTTCTGCGTCACAGTCGATTTCGACTCGCTCGAAGACGACTCCGTCACCGTTCGCGACCGCGACGAGATGACCCAGC
AGCGTATTCCGATCGGCGGCGTGGCCGATCATCTCGCCAAAACCCTCAAGGGCTGCTAG

Upstream 100 bases:

>100_bases
GCCGCAAGGCGACCGAGGTAGAAAGCGTTTTGTCCGGCCCTTAGGCTGTCCAGGTCAATTACTGCTGTCTTGTGGACCTC
AAGAGGAGCCTGAGCGAATC

Downstream 100 bases:

>100_bases
CCGAGGAGCAGAAATGACTGACGTTCAGAATCACATCGGAATCGATCCCGCCAGCGCGCCGATCGAGGCTCCCGCGGCCG
AGGCGCAGGTCCGCGCCGAC

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MAAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKENIKKQWWRSVVTSRDDVVGLDSSVILPRQV
WVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYSEKEAKKGLTIAPESVPMTEIVCPDCGNKGQWTEPRDFNMMLKTYLG
PIETEEGLHYLRPETAQGIFINFKNVVTTSRQKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHK
YWIDTRLQWYVDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANRTDFDLSTHAKHSGEDLSYYD
QAEDRRYTPYVIEPAAGLTRSFMAFLVDAYHEDEAPNAKGGVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAE
LRQSWNVDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDSVTVRDRDEMTQQRIPIGGVADHLAKTLKGC

Sequences:

>Translated_472_residues
MAAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKENIKKQWWRSVVTSRDDVVGLDSSVILPRQV
WVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYSEKEAKKGLTIAPESVPMTEIVCPDCGNKGQWTEPRDFNMMLKTYLG
PIETEEGLHYLRPETAQGIFINFKNVVTTSRQKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHK
YWIDTRLQWYVDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANRTDFDLSTHAKHSGEDLSYYD
QAEDRRYTPYVIEPAAGLTRSFMAFLVDAYHEDEAPNAKGGVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAE
LRQSWNVDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDSVTVRDRDEMTQQRIPIGGVADHLAKTLKGC
>Mature_471_residues
AAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKENIKKQWWRSVVTSRDDVVGLDSSVILPRQVW
VASGHVEVFNDPLVECLNCHKRHRQDHLQEAYSEKEAKKGLTIAPESVPMTEIVCPDCGNKGQWTEPRDFNMMLKTYLGP
IETEEGLHYLRPETAQGIFINFKNVVTTSRQKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHKY
WIDTRLQWYVDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANRTDFDLSTHAKHSGEDLSYYDQ
AEDRRYTPYVIEPAAGLTRSFMAFLVDAYHEDEAPNAKGGVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAEL
RQSWNVDFDDAGAIGRRYRRQDEIGTPFCVTVDFDSLEDDSVTVRDRDEMTQQRIPIGGVADHLAKTLKGC

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=356, Percent_Identity=31.1797752808989, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI70887790, Length=481, Percent_Identity=23.2848232848233, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554996, Length=379, Percent_Identity=29.287598944591, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564541, Length=379, Percent_Identity=29.287598944591, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319597, Length=401, Percent_Identity=28.6783042394015, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325338, Length=397, Percent_Identity=27.2040302267003, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24664462, Length=399, Percent_Identity=29.8245614035088, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21357965, Length=399, Percent_Identity=29.8245614035088, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 53508; Mature: 53377

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50862 AA_TRNA_LIGASE_II ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKENIKKQWWRSV
CCCCCCCCHHHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VTSRDDVVGLDSSVILPRQVWVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYSEKEAKK
HCCCCCEECCCCCEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTIAPESVPMTEIVCPDCGNKGQWTEPRDFNMMLKTYLGPIETEEGLHYLRPETAQGIF
CCEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
INFKNVVTTSRQKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHK
EEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHCCEEEEECCCCCCHHHH
YWIDTRLQWYVDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANR
HHHCCEEEEEEEECCCCCCCEEEECCHHHHHCCCCCEEEEEEEECCCCCCCHHHCCCCCC
TDFDLSTHAKHSGEDLSYYDQAEDRRYTPYVIEPAAGLTRSFMAFLVDAYHEDEAPNAKG
CCCCCHHCCCCCCCCCCHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
GVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAELRQSWNVDFDDAGAIGRRYR
CCCCEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RQDEIGTPFCVTVDFDSLEDDSVTVRDRDEMTQQRIPIGGVADHLAKTLKGC
HHHCCCCCEEEEEECCCCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAKPNAAGKKIEAVVNLAKRRGLVYPCGEIYGGTKSAWDYGPLGVELKENIKKQWWRSV
CCCCCCCHHHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VTSRDDVVGLDSSVILPRQVWVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYSEKEAKK
HCCCCCEECCCCCEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTIAPESVPMTEIVCPDCGNKGQWTEPRDFNMMLKTYLGPIETEEGLHYLRPETAQGIF
CCEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
INFKNVVTTSRQKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAPEWHK
EEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHCCEEEEECCCCCCHHHH
YWIDTRLQWYVDLGIDPENLRLYDHPKEKLSHYSDGTVDIEYKFGFSGNPWGELEGIANR
HHHCCEEEEEEEECCCCCCCEEEECCHHHHHCCCCCEEEEEEEECCCCCCCHHHCCCCCC
TDFDLSTHAKHSGEDLSYYDQAEDRRYTPYVIEPAAGLTRSFMAFLVDAYHEDEAPNAKG
CCCCCHHCCCCCCCCCCHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
GVDTRTVLRLDPRLAPVKVAVLPLSRNADLSPRAKALAAELRQSWNVDFDDAGAIGRRYR
CCCCEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
RQDEIGTPFCVTVDFDSLEDDSVTVRDRDEMTQQRIPIGGVADHLAKTLKGC
HHHCCCCCEEEEEECCCCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA