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The map label for this gene is lcfA [H]

Identifier: 169627392

GI number: 169627392

Start: 285782

End: 287347

Strand: Direct

Name: lcfA [H]

Synonym: MAB_0287

Alternate gene names: 169627392

Gene position: 285782-287347 (Clockwise)

Preceding gene: 169627391

Following gene: 169627393

Centisome position: 5.64

GC content: 65.01

Gene sequence:

>1566_bases
ATGATCCTGCAGCGCATCGGAAACCGCGGTATCAAACTCGGTACGCTGTTCGAGCGCGCGGCCCGGCGGCACCCTGACAA
CACCCTGACCCTGGATCATCGGCCGTCGCTGGCCCCTCAGCTGGAGGGCACCGCGACCATCGCCGCGGTGGCGTCCGCCG
TCGACGACATCGCGCGGCGGCTGCGGGCCGCCGGAGTTGCTCCCGGTGAAAAGCTGGTCATCCACAAGTCGGACGGTTTC
GACATTACCCTGGCGGCATGCGCCGCCGCGCGTGTGGGCGCGATACCAGTGCTGTTGTCTCCCAAGCTCGATGGTTCAAC
GGTGGCAACGCTGATCGGACGGGTGGGCAACCCTGCGCTGCTGACCGACGCGGCCAAGCTCGACGGCGAACTGGCCGACG
AGCCCATCGCCGAGATCACCTCGCGTGTTCTGCTCGCCGAAGGCGTTCACCCACAGGCGGTGACACTTTCGGCGCTCACC
CCCGCGTGCCCGGCACCGGCGGTCATCCCCAGCCCCCATGATCCTGCGCTCATCACGCACACCTCAGGTACCACCGGAGT
GCCCAAACTGGCAGTGCACACCAACTTCACCTTCGAGGCGAGATATCGTCCGCAGGCCGCCGTCGCCGCACTGGTGCGCC
GCCGCGAACCCATTGTCATCCATGTCTCGTTCGTGCATTCGCGTCTGGTAACCGCGTTGGCCATCGCCATCTTGCGCGGC
TTCCCCGTGGTAGTGCTTGTCGACGACGCACCTGAGCGCGCCGCGGAGATCTTCCTGCGCGTTAAACCGGGAATCCTTGA
GGCTCACCCGAATACGTTCATCAACTGGGAGGTATTGGCCGAGGACCCGCGTCGCCCGCTGGCCTCGGTGAAGTACTTCA
GCAGCACCTTCGACGCGATTCACCCGCGCACGGTGCGCACACTGCTCGCCGCCTCGCAGCGCCGACGCCCGCTGTTCGGC
CAGCTGTATGGCCAAAGTGAGGTCGGTCCCATCGTGGCGCGTGGTTTCAGCCGGTTCCGCTCCGCGGACTCCGATGGTCG
TTGCGTCGGCCATCCGTTCCCGGGCATGACCGACGTGCGGATCGTTTCGCGTAACGGACAACTGCCTTCTGCGGACAATC
CCGGGTACATCGAGGTGCGCACCGATGGCCGGATTCGCACGTATCTGGGCGAGCAGGAACGCTACGAGAAGCAGCTCGAC
AACGGCTGGTGGCGGATGGGTGATGTCGGCTACCGCACCCGTTGGGGATGTATTCACCTACTGGACCGCGAGGTCGATCT
GATCGACGGTTTCGGCAGTACTCTGGCGGCCGAGGATCGCTTGTTCCTAGCGGTCGATGAGCTCACCGAGGTGATCATCG
TTGCCGGCCCCAACGGACTTGCCCAGCCGGTCGTCTGCACGAAAAACAATGTGCCGCTGAATCGTAACGCATGGGATGCC
GCTGCGGCGAAATTGCCGCCGATGGCGCCGCCACTGCACCTACGCCTCGATGAACTTCCGCAGACCGCCACCACGAAGAT
CAAGCGGCTGGAACTGTCGGCACGTATCGGAGCGGGGTCCCTCTGA

Upstream 100 bases:

>100_bases
AGCAGCGCTTCGTCCGTGAATGGGGCGACAAGCTTCGGGCCGATATGCAGGCCACCGTCGATGCGATCGCGCGTATTACC
CAGGAAGCGGGCGTTCCCCA

Downstream 100 bases:

>100_bases
TGAGCCGGCTCATCGTCATCGGTGGAGGCATCGGCGGATTGGCTGTCGCACTGAGCGTCGCCGCGTCCGGTAACGAGGTT
GTGGTGTTGGAGCGGGCGCG

Product: fatty-acid-CoA ligase FadD

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MILQRIGNRGIKLGTLFERAARRHPDNTLTLDHRPSLAPQLEGTATIAAVASAVDDIARRLRAAGVAPGEKLVIHKSDGF
DITLAACAAARVGAIPVLLSPKLDGSTVATLIGRVGNPALLTDAAKLDGELADEPIAEITSRVLLAEGVHPQAVTLSALT
PACPAPAVIPSPHDPALITHTSGTTGVPKLAVHTNFTFEARYRPQAAVAALVRRREPIVIHVSFVHSRLVTALAIAILRG
FPVVVLVDDAPERAAEIFLRVKPGILEAHPNTFINWEVLAEDPRRPLASVKYFSSTFDAIHPRTVRTLLAASQRRRPLFG
QLYGQSEVGPIVARGFSRFRSADSDGRCVGHPFPGMTDVRIVSRNGQLPSADNPGYIEVRTDGRIRTYLGEQERYEKQLD
NGWWRMGDVGYRTRWGCIHLLDREVDLIDGFGSTLAAEDRLFLAVDELTEVIIVAGPNGLAQPVVCTKNNVPLNRNAWDA
AAAKLPPMAPPLHLRLDELPQTATTKIKRLELSARIGAGSL

Sequences:

>Translated_521_residues
MILQRIGNRGIKLGTLFERAARRHPDNTLTLDHRPSLAPQLEGTATIAAVASAVDDIARRLRAAGVAPGEKLVIHKSDGF
DITLAACAAARVGAIPVLLSPKLDGSTVATLIGRVGNPALLTDAAKLDGELADEPIAEITSRVLLAEGVHPQAVTLSALT
PACPAPAVIPSPHDPALITHTSGTTGVPKLAVHTNFTFEARYRPQAAVAALVRRREPIVIHVSFVHSRLVTALAIAILRG
FPVVVLVDDAPERAAEIFLRVKPGILEAHPNTFINWEVLAEDPRRPLASVKYFSSTFDAIHPRTVRTLLAASQRRRPLFG
QLYGQSEVGPIVARGFSRFRSADSDGRCVGHPFPGMTDVRIVSRNGQLPSADNPGYIEVRTDGRIRTYLGEQERYEKQLD
NGWWRMGDVGYRTRWGCIHLLDREVDLIDGFGSTLAAEDRLFLAVDELTEVIIVAGPNGLAQPVVCTKNNVPLNRNAWDA
AAAKLPPMAPPLHLRLDELPQTATTKIKRLELSARIGAGSL
>Mature_521_residues
MILQRIGNRGIKLGTLFERAARRHPDNTLTLDHRPSLAPQLEGTATIAAVASAVDDIARRLRAAGVAPGEKLVIHKSDGF
DITLAACAAARVGAIPVLLSPKLDGSTVATLIGRVGNPALLTDAAKLDGELADEPIAEITSRVLLAEGVHPQAVTLSALT
PACPAPAVIPSPHDPALITHTSGTTGVPKLAVHTNFTFEARYRPQAAVAALVRRREPIVIHVSFVHSRLVTALAIAILRG
FPVVVLVDDAPERAAEIFLRVKPGILEAHPNTFINWEVLAEDPRRPLASVKYFSSTFDAIHPRTVRTLLAASQRRRPLFG
QLYGQSEVGPIVARGFSRFRSADSDGRCVGHPFPGMTDVRIVSRNGQLPSADNPGYIEVRTDGRIRTYLGEQERYEKQLD
NGWWRMGDVGYRTRWGCIHLLDREVDLIDGFGSTLAAEDRLFLAVDELTEVIIVAGPNGLAQPVVCTKNNVPLNRNAWDA
AAAKLPPMAPPLHLRLDELPQTATTKIKRLELSARIGAGSL

Specific function: Unknown

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 56309; Mature: 56309

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILQRIGNRGIKLGTLFERAARRHPDNTLTLDHRPSLAPQLEGTATIAAVASAVDDIARR
CCHHHHCCCCCEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LRAAGVAPGEKLVIHKSDGFDITLAACAAARVGAIPVLLSPKLDGSTVATLIGRVGNPAL
HHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCE
LTDAAKLDGELADEPIAEITSRVLLAEGVHPQAVTLSALTPACPAPAVIPSPHDPALITH
EEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
TSGTTGVPKLAVHTNFTFEARYRPQAAVAALVRRREPIVIHVSFVHSRLVTALAIAILRG
CCCCCCCCEEEEEECEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCC
FPVVVLVDDAPERAAEIFLRVKPGILEAHPNTFINWEVLAEDPRRPLASVKYFSSTFDAI
CCEEEEECCCCHHHHHEEEEECCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
HPRTVRTLLAASQRRRPLFGQLYGQSEVGPIVARGFSRFRSADSDGRCVGHPFPGMTDVR
CHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCEEE
IVSRNGQLPSADNPGYIEVRTDGRIRTYLGEQERYEKQLDNGWWRMGDVGYRTRWGCIHL
EEECCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHCCCCEEECCCCCCCCCCEEEE
LDREVDLIDGFGSTLAAEDRLFLAVDELTEVIIVAGPNGLAQPVVCTKNNVPLNRNAWDA
ECCCCHHHHCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCEEEECCCCCCCCCCHHH
AAAKLPPMAPPLHLRLDELPQTATTKIKRLELSARIGAGSL
HHHCCCCCCCCCEEEHHHCCCHHHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MILQRIGNRGIKLGTLFERAARRHPDNTLTLDHRPSLAPQLEGTATIAAVASAVDDIARR
CCHHHHCCCCCEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LRAAGVAPGEKLVIHKSDGFDITLAACAAARVGAIPVLLSPKLDGSTVATLIGRVGNPAL
HHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCCE
LTDAAKLDGELADEPIAEITSRVLLAEGVHPQAVTLSALTPACPAPAVIPSPHDPALITH
EEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEE
TSGTTGVPKLAVHTNFTFEARYRPQAAVAALVRRREPIVIHVSFVHSRLVTALAIAILRG
CCCCCCCCEEEEEECEEEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCC
FPVVVLVDDAPERAAEIFLRVKPGILEAHPNTFINWEVLAEDPRRPLASVKYFSSTFDAI
CCEEEEECCCCHHHHHEEEEECCCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
HPRTVRTLLAASQRRRPLFGQLYGQSEVGPIVARGFSRFRSADSDGRCVGHPFPGMTDVR
CHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCEEE
IVSRNGQLPSADNPGYIEVRTDGRIRTYLGEQERYEKQLDNGWWRMGDVGYRTRWGCIHL
EEECCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHCCCCEEECCCCCCCCCCEEEE
LDREVDLIDGFGSTLAAEDRLFLAVDELTEVIIVAGPNGLAQPVVCTKNNVPLNRNAWDA
ECCCCHHHHCCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCEEEECCCCCCCCCCHHH
AAAKLPPMAPPLHLRLDELPQTATTKIKRLELSARIGAGSL
HHHCCCCCCCCCEEEHHHCCCHHHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]