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The map label for this gene is uppP

Identifier: 169833901

GI number: 169833901

Start: 511007

End: 511852

Strand: Direct

Name: uppP

Synonym: SPH_0565

Alternate gene names: 169833901

Gene position: 511007-511852 (Clockwise)

Preceding gene: 169832979

Following gene: 169833255

Centisome position: 22.76

GC content: 40.19

Gene sequence:

>846_bases
ATGTATCTTATTGAAATTTTAAAATCTATCTTCTTCGGGATTGTTGAAGGAATTACGGAATGGTTGCCGATTTCCAGTAC
AGGTCACTTGATTTTAGCAGAGGAGTTTATCCAATACCAAAATCAAAATGAAGCCTTTATGTCCATGTTTAATGTCGTGA
TTCAGCTTGGTGCTATTTTAGCAGTTATGGTGATTTATTTTAACAAGCTCAATCCTTTTAAACCGACTAAGGACAAACAG
GAAGTTCGTAAGACTTGGAGACTATGGTTGAAGGTCTTGATTGCCACTTTGCCTTTACTTGGTGTCTTTAAATTTGATGA
TTGGTTTGATACCCACTTCCATAACATGGTTTCAGTTGCTCTCATGTTGATTATCTACGGGGTTGCCTTCATCTATTTGG
AAAAGCGCAATAAAGCGCGTGCTATCGAGCCAAGTGTAACAGAGTTGGACAAGCTTCCTTATACGACCGCTTTCTATATC
GGACTCTTCCAAGTTCTTGCTCTTTTACCAGGGACTAGCCGTTCAGGTGCAACGATTGTCGGTGGTTTGTTAAATGGAAC
CAGTCGTTCAGTTGTGACAGAATTTACCTTCTATCTTGGGATTCCCGTTATGTTTGGAGCTAGTGCCTTAAAGATTTTCA
AATTTGTGAAAGCCGGAGAACTCTTGAGCTTTGGGCAATTGTTTTTGCTCTTGGTCGCGATGGGAGTAGCTTTTGCGGTC
AGCATGGTGGCTATTCGCTTCTTGACCAGCTATGTGAAAAAACACGACTTCACCCTTTTTGGTAAATACCGTATCGTGCT
TGGTAGTGTTTTGCTACTTTACAGTTTTGTCCGTTTATTTGTATAA

Upstream 100 bases:

>100_bases
GATTGGAGGAAATGAACTAATCCACAGTGGCTTATTCCAAGTATACCACTTGGGCTTTGGCAGTAGCTAACTGCGTTAAA
TATAATATAAGGAGAAATAT

Downstream 100 bases:

>100_bases
GAAAAACCTTGAAGGGGCAACTCTTCAAGGTTTTATACTCTTAGAAAATCTCTTCAAACCGCGTCAGCTTTATCTGCAAC
CTCAAAACAGTGTTTTGAGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQ
EVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAV
SMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV

Sequences:

>Translated_281_residues
MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQ
EVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAV
SMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV
>Mature_281_residues
MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQ
EVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAV
SMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=276, Percent_Identity=35.5072463768116, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_STRP2 (Q04M23)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_815925.1
- STRING:   Q04M23
- EnsemblBacteria:   EBSTRT00000019444
- GeneID:   4441316
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0417
- eggNOG:   COG1968
- GeneTree:   EBGT00050000027344
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31810; Mature: 31810

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x164c8e28)-; HASH(0x1619dd38)-; HASH(0x952c4b0)-; HASH(0x952c240)-; HASH(0x16924c5c)-; HASH(0x15e06ea8)-; HASH(0x15b26670)-; HASH(0x14ce571c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA