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The map label for this gene is yggV [C]

Identifier: 169824270

GI number: 169824270

Start: 637410

End: 638012

Strand: Direct

Name: yggV [C]

Synonym: FMG_0573

Alternate gene names: 169824270

Gene position: 637410-638012 (Clockwise)

Preceding gene: 169824269

Following gene: 169824271

Centisome position: 35.46

GC content: 30.85

Gene sequence:

>603_bases
ATGAAGAAAATATATTTATCTACAGGAAACAAAGGAAAAGTTTCTGAAATAAAAGAAATACTTTCTGATTTAACATATGA
TGTGTATTCTAAATCTGAATTGGGTATAAATGAAGATGCAGTGGAAGATGCAGAAACTTTAGAAGAAAATTCGCTTATCA
AAGCTAAATTTCTAAAAAAATACACAGATGATATTGTAATGAGTGATGACACTGGGCTTTTCGTAAATTCTTTGGATGGA
AGACCTGGAGTATACTCTGCGAGATTTGCAGGAGATGAATGTGACGATAGTAAAAATCGTAAAAAACTTTTATCTGAATT
GAAAGATAAAGAAGATAGAAGTGCTTATTTTGAAACTGTGATTACAATCATAGATTTAAATAATGAAATTCATCAAGCAA
AAGGCAGAGTGGATGGCAAGATTTTACTTGAAGAATGTGGAGAACATGGTTTCGGATATGATAGTATATTCATGCCAGAT
GGCTACGATAAAAGTTTTGCACAAATGGAAGATTGTGAGAAAAACAAGATTAGTCACAGAAAAAGAGCTTTAGAAAATGC
CAAAATCATCTTGAAAGGTTTAAATGAAAGTAGCAATAATTAG

Upstream 100 bases:

>100_bases
AAGATCGTGCAATAGGATTCTTAGTTGGACAATGCATGAAAAAGTCAAAAGGTAAAGGAAATCCACAAAAATTCAACGAA
TTAATAAAAGAGAAAATCTA

Downstream 100 bases:

>100_bases
TGATACACATAATAAAATAGCAAAAGTTTATGACTATTTATTTGATAAAGAAATTGACATCATCGTTCACTTAGGAGATG
TGTGCGATGATGCAATTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKKIYLSTGNKGKVSEIKEILSDLTYDVYSKSELGINEDAVEDAETLEENSLIKAKFLKKYTDDIVMSDDTGLFVNSLDG
RPGVYSARFAGDECDDSKNRKKLLSELKDKEDRSAYFETVITIIDLNNEIHQAKGRVDGKILLEECGEHGFGYDSIFMPD
GYDKSFAQMEDCEKNKISHRKRALENAKIILKGLNESSNN

Sequences:

>Translated_200_residues
MKKIYLSTGNKGKVSEIKEILSDLTYDVYSKSELGINEDAVEDAETLEENSLIKAKFLKKYTDDIVMSDDTGLFVNSLDG
RPGVYSARFAGDECDDSKNRKKLLSELKDKEDRSAYFETVITIIDLNNEIHQAKGRVDGKILLEECGEHGFGYDSIFMPD
GYDKSFAQMEDCEKNKISHRKRALENAKIILKGLNESSNN
>Mature_200_residues
MKKIYLSTGNKGKVSEIKEILSDLTYDVYSKSELGINEDAVEDAETLEENSLIKAKFLKKYTDDIVMSDDTGLFVNSLDG
RPGVYSARFAGDECDDSKNRKKLLSELKDKEDRSAYFETVITIIDLNNEIHQAKGRVDGKILLEECGEHGFGYDSIFMPD
GYDKSFAQMEDCEKNKISHRKRALENAKIILKGLNESSNN

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=185, Percent_Identity=31.8918918918919, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31657144, Length=139, Percent_Identity=33.0935251798561, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=38.8888888888889, Blast_Score=130, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17556833, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322529, Length=192, Percent_Identity=30.7291666666667, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19920712, Length=184, Percent_Identity=30.9782608695652, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22570; Mature: 22570

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYLSTGNKGKVSEIKEILSDLTYDVYSKSELGINEDAVEDAETLEENSLIKAKFLKK
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
YTDDIVMSDDTGLFVNSLDGRPGVYSARFAGDECDDSKNRKKLLSELKDKEDRSAYFETV
HHHCEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
ITIIDLNNEIHQAKGRVDGKILLEECGEHGFGYDSIFMPDGYDKSFAQMEDCEKNKISHR
HHHHCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHH
KRALENAKIILKGLNESSNN
HHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MKKIYLSTGNKGKVSEIKEILSDLTYDVYSKSELGINEDAVEDAETLEENSLIKAKFLKK
CCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
YTDDIVMSDDTGLFVNSLDGRPGVYSARFAGDECDDSKNRKKLLSELKDKEDRSAYFETV
HHHCEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
ITIIDLNNEIHQAKGRVDGKILLEECGEHGFGYDSIFMPDGYDKSFAQMEDCEKNKISHR
HHHHCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHH
KRALENAKIILKGLNESSNN
HHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA