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The map label for this gene is yvtA [H]

Identifier: 169824164

GI number: 169824164

Start: 525353

End: 526555

Strand: Direct

Name: yvtA [H]

Synonym: FMG_0467

Alternate gene names: 169824164

Gene position: 525353-526555 (Clockwise)

Preceding gene: 169824163

Following gene: 169824165

Centisome position: 29.23

GC content: 33.83

Gene sequence:

>1203_bases
ATGGACAGAGACCCTTACTCTGATTACAATGATTATATAAGAAAAAGAAGAGACGGCTTAAGTGAGAGAAAAGTCGAAAA
TATGATAAAAAAAGAAATCGCTAAGAACAAACCTAAAATTGGTTGGCTCAAAGCATTAACAATATTTTTATTAATTTATT
CTTTGGTTATGAGTTATTTTGTAGTTAAAAATATGACTGGAATTACTGAAACTATTAACAAGAATGGTCAAGTGGAAAGC
AGTACTATTTCTATAAAAAATAGTAGCGTTTCAACAGAAAATGCTGTAGCTAAGAAATCTTTGGATTCTGTTGTTGGTAT
TACAACTGTAGGAGTCCAAGAAAATATGTTTTTCCAAGGCAGAGTTGTTGAAGGCGTTGGTAGTGGTGTTGTTGTTAGCA
AAGATGGATACATTTTAACTAACGCACACGTTGTACAAGATGGTAAAGCCGAAAAAATTGACGTTTTACTTACAAATGGC
AAGAAATCATCTGCAAAATTATTGTGGTATGATACAACTTTGGACCTTGCAGTAATAAAGACTGACTTAACAGGGTTAAA
ACCAGTTGAAATGGGAGATAGCGACAAAGTTCAAATAGGAGACAAGGCAATTGCTATCGGTAATCCACTTGGATTGGATT
TGCAATCAACATTGACTAGTGGATATATTTCTGGAAAAGATAGAACAATCACTTTACAAAATGGCTTACAAATGGACGGA
TTGATGCAAACAGACGCAGCTATCAACTCAGGTAACAGTGGTGGTGGACTTTTCGATCAAGAAGGTAAATTAATTGGTAT
AAATACTGCAAAAGCTTCTGCAGAAGGAATCGGATTTACTATTCCAATCAATGTGGCAAAGTCTATTGTTGATAATATTA
TTACAGGTGGATCTTTTGATGGAGTTAAGTTGGGAATTAGTGGTGTTGATGTCAAGACTTTCCAACAAGCTACTGGTCAA
AAATTATCCATTGACAAGGGAATTTATGTAGTAGAAGTTGTAAAAGGATCTTCTGCACAAAAAGCTGGCGTTACTAGAGG
AGATATCATAACGAAAGTAAATGGTAAACAAATCAATACGATGAGTTCTTTGAAGAAGGTATTGCTTGAAGTTAGACCGA
AACAAAAAGGCAAAATTACAGTATACAGAGATGGTAGTACAAAAGATTTGGATATTGAATTTAGTACTTTAGAACAAAAA
TAA

Upstream 100 bases:

>100_bases
AACATAAAGTTTGATTTTTCGTAAACTTTAGTACACTTTTACTCACAGTTAAAACACATTTGATTGATAAAGTATAAGTA
TCAAAGATGGAGGTGCAAAT

Downstream 100 bases:

>100_bases
GTTATCACGTTTTTTCCTTCCTTAATTTGCGTGAGATTTGAAATATATAAATTTGAAAGCGGTAGTGAGAGCTATCGCTT
TTAAATTGTAAAAAACAAGA

Product: trypsin-like serine protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDRDPYSDYNDYIRKRRDGLSERKVENMIKKEIAKNKPKIGWLKALTIFLLIYSLVMSYFVVKNMTGITETINKNGQVES
STISIKNSSVSTENAVAKKSLDSVVGITTVGVQENMFFQGRVVEGVGSGVVVSKDGYILTNAHVVQDGKAEKIDVLLTNG
KKSSAKLLWYDTTLDLAVIKTDLTGLKPVEMGDSDKVQIGDKAIAIGNPLGLDLQSTLTSGYISGKDRTITLQNGLQMDG
LMQTDAAINSGNSGGGLFDQEGKLIGINTAKASAEGIGFTIPINVAKSIVDNIITGGSFDGVKLGISGVDVKTFQQATGQ
KLSIDKGIYVVEVVKGSSAQKAGVTRGDIITKVNGKQINTMSSLKKVLLEVRPKQKGKITVYRDGSTKDLDIEFSTLEQK

Sequences:

>Translated_400_residues
MDRDPYSDYNDYIRKRRDGLSERKVENMIKKEIAKNKPKIGWLKALTIFLLIYSLVMSYFVVKNMTGITETINKNGQVES
STISIKNSSVSTENAVAKKSLDSVVGITTVGVQENMFFQGRVVEGVGSGVVVSKDGYILTNAHVVQDGKAEKIDVLLTNG
KKSSAKLLWYDTTLDLAVIKTDLTGLKPVEMGDSDKVQIGDKAIAIGNPLGLDLQSTLTSGYISGKDRTITLQNGLQMDG
LMQTDAAINSGNSGGGLFDQEGKLIGINTAKASAEGIGFTIPINVAKSIVDNIITGGSFDGVKLGISGVDVKTFQQATGQ
KLSIDKGIYVVEVVKGSSAQKAGVTRGDIITKVNGKQINTMSSLKKVLLEVRPKQKGKITVYRDGSTKDLDIEFSTLEQK
>Mature_400_residues
MDRDPYSDYNDYIRKRRDGLSERKVENMIKKEIAKNKPKIGWLKALTIFLLIYSLVMSYFVVKNMTGITETINKNGQVES
STISIKNSSVSTENAVAKKSLDSVVGITTVGVQENMFFQGRVVEGVGSGVVVSKDGYILTNAHVVQDGKAEKIDVLLTNG
KKSSAKLLWYDTTLDLAVIKTDLTGLKPVEMGDSDKVQIGDKAIAIGNPLGLDLQSTLTSGYISGKDRTITLQNGLQMDG
LMQTDAAINSGNSGGGLFDQEGKLIGINTAKASAEGIGFTIPINVAKSIVDNIITGGSFDGVKLGISGVDVKTFQQATGQ
KLSIDKGIYVVEVVKGSSAQKAGVTRGDIITKVNGKQINTMSSLKKVLLEVRPKQKGKITVYRDGSTKDLDIEFSTLEQK

Specific function: May be involved in processing, maturation, or secretion of extracellular enzymes [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=34.2560553633218, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4506141, Length=266, Percent_Identity=33.8345864661654, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22129776, Length=268, Percent_Identity=36.5671641791045, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7019477, Length=278, Percent_Identity=32.0143884892086, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789629, Length=281, Percent_Identity=39.8576512455516, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786356, Length=280, Percent_Identity=37.5, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789630, Length=303, Percent_Identity=35.3135313531353, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646839, Length=354, Percent_Identity=29.9435028248588, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43015; Mature: 43015

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRDPYSDYNDYIRKRRDGLSERKVENMIKKEIAKNKPKIGWLKALTIFLLIYSLVMSYF
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VVKNMTGITETINKNGQVESSTISIKNSSVSTENAVAKKSLDSVVGITTVGVQENMFFQG
HHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEC
RVVEGVGSGVVVSKDGYILTNAHVVQDGKAEKIDVLLTNGKKSSAKLLWYDTTLDLAVIK
EEEECCCCCEEEECCCEEEEEEEEEECCCCCEEEEEEECCCCCCCEEEEEECCEEEEEEE
TDLTGLKPVEMGDSDKVQIGDKAIAIGNPLGLDLQSTLTSGYISGKDRTITLQNGLQMDG
ECCCCCCEECCCCCCCEEECCEEEEECCCCCCCHHHHHHHCEECCCCCEEEECCCCCCCC
LMQTDAAINSGNSGGGLFDQEGKLIGINTAKASAEGIGFTIPINVAKSIVDNIITGGSFD
EECCCHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
GVKLGISGVDVKTFQQATGQKLSIDKGIYVVEVVKGSSAQKAGVTRGDIITKVNGKQINT
CEEEEECCCCHHHHHHHCCCEEEECCCEEEEEEEECCCCCCCCCCCCCEEEEECCCEEHH
MSSLKKVLLEVRPKQKGKITVYRDGSTKDLDIEFSTLEQK
HHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MDRDPYSDYNDYIRKRRDGLSERKVENMIKKEIAKNKPKIGWLKALTIFLLIYSLVMSYF
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VVKNMTGITETINKNGQVESSTISIKNSSVSTENAVAKKSLDSVVGITTVGVQENMFFQG
HHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCEEEEC
RVVEGVGSGVVVSKDGYILTNAHVVQDGKAEKIDVLLTNGKKSSAKLLWYDTTLDLAVIK
EEEECCCCCEEEECCCEEEEEEEEEECCCCCEEEEEEECCCCCCCEEEEEECCEEEEEEE
TDLTGLKPVEMGDSDKVQIGDKAIAIGNPLGLDLQSTLTSGYISGKDRTITLQNGLQMDG
ECCCCCCEECCCCCCCEEECCEEEEECCCCCCCHHHHHHHCEECCCCCEEEECCCCCCCC
LMQTDAAINSGNSGGGLFDQEGKLIGINTAKASAEGIGFTIPINVAKSIVDNIITGGSFD
EECCCHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCC
GVKLGISGVDVKTFQQATGQKLSIDKGIYVVEVVKGSSAQKAGVTRGDIITKVNGKQINT
CEEEEECCCCHHHHHHHCCCEEEECCCEEEEEEEECCCCCCCCCCCCCEEEEECCCEEHH
MSSLKKVLLEVRPKQKGKITVYRDGSTKDLDIEFSTLEQK
HHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10692364; 9353931; 9384377; 10568751; 11133960 [H]