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The map label for this gene is selA [H]

Identifier: 169824130

GI number: 169824130

Start: 489484

End: 490890

Strand: Direct

Name: selA [H]

Synonym: FMG_0433

Alternate gene names: 169824130

Gene position: 489484-490890 (Clockwise)

Preceding gene: 169824120

Following gene: 169824131

Centisome position: 27.23

GC content: 31.06

Gene sequence:

>1407_bases
ATGGGAACTAATTTACAAGAAATGTTTAAGAAACTTCCGCAAGTTTCAGAAATTTTAGAATCGGAAGAAATTTTACAAGC
GTACGAAGAATATCCTGAAAGTTTAATAAAAGACTCAGTAAGAGAATCGATAGAATTTTTTAGAAATAGAATATTAAATA
AAGAAGAGTTTGACTTTTATAACAAAGATGTTATTGACAAGGCATTTGAATTGATGGACAAAAACTTCTCGCCATCATTG
AAACCTGTAATAAATGCAACAGGAGTTATTTTACATACAAACCTTGGTAGATCATTATTAAATGAAAAAGTAGTCGATAA
CTTATGCAAAATTGCTGGGAATTATTCTAACTTAGAATATGACTTAGATGAAGGAAAAAGAGGCTCAAGATATGTCCATG
CTGTAGAACTTTTGAAAAGAATTACAAAAGCTGAAGATGCTGTAGTAGTAAATAACAATGCGTCGGCAGTTTTTCTTACT
CTAAATACTTTGGCTCAAAACAAAGAAGCTATTATAAGTAGGGGAGAATTGGTAGAAGTTGGAGGATCTTTTAGAATATC
TTCCATTATGGAAAAATCTGGAGCGAAGTTAGTAGAAGTTGGTTCAACTAACAAAACCCACATGTACGATTATGAAGATA
ATATTAATGAAGAAACTGCTCTTATTATGAAGGTTCACACTTCAAATTATTCTGTAGTAGGATTTAGTGAAAGTGTAAGT
GGAGATGAATTGAGACAATTGTGTGATGAAAAAGGCATACATTTAATAGAAGATTTGGGTTCTGGTTCTTTAATAGATTT
GTCGAAGTTTGGTCTAAGCTACGAAAGAACTGTCAAGGACTGTATTAATGAAGGAATTGATTTGGTATCATTCTCTGGAG
ACAAGATTTTAGGTGGTCCACAAGCTGGAATTATTGTAGGTAAGAAAGAATTGATATCTAAGATTAAGAAAAATCAATTA
TTAAGAGCATTCAGAGTTGACAAGTTTACATTAGGAGCATTGGAAGAAACACTCAAATTTTACTTAGATGAAGAAAAAGC
AATTGCAAATATTCCTACTTTGAAGATGATATCTATGCCAAAAGAAGAAATTCTTCGAAAAGCAGAAAAACTAAAATCTA
TGATTGAAAAAGAAGTAGACTTGAATATGGAAATTGTTGAATCGCAAAGCGAAGTAGGAGGCGGGGCATATCCATTAGAT
AAATTAGATTCATATTCAATTGCTATAAAACCAGATATGAAGGTGTCTGAATTTGAAAGAGGTCTCAGATTATCAAAAGA
TCACATTATAGGAACTGTTCACGATGATACATTCTTCATGGATTTAAGATGTATTTTTGAAAAAGATTTTGAAAGAATTG
TAAAAGTGATTAAACTCAATACTATTTTGAAAAAAATGCCAATGTGA

Upstream 100 bases:

>100_bases
TTATATGATAGACAATTCTCTGCTCTTATATTATAATTTACTCATAAGTTAATGTCAAATACGTATATATTATATAGAAG
AAAATGGAGGCAAATAAAAA

Downstream 100 bases:

>100_bases
TTTAACTGAATATTATTATAAAATCTTATATGAAAATCCCGAATTGATAATTCGGGATTTTTGATTTATTGAACAAAAAT
TTTAGAAAAAATGTAGGAAA

Product: L-seryl-tRNA(Sec) selenium transferase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MGTNLQEMFKKLPQVSEILESEEILQAYEEYPESLIKDSVRESIEFFRNRILNKEEFDFYNKDVIDKAFELMDKNFSPSL
KPVINATGVILHTNLGRSLLNEKVVDNLCKIAGNYSNLEYDLDEGKRGSRYVHAVELLKRITKAEDAVVVNNNASAVFLT
LNTLAQNKEAIISRGELVEVGGSFRISSIMEKSGAKLVEVGSTNKTHMYDYEDNINEETALIMKVHTSNYSVVGFSESVS
GDELRQLCDEKGIHLIEDLGSGSLIDLSKFGLSYERTVKDCINEGIDLVSFSGDKILGGPQAGIIVGKKELISKIKKNQL
LRAFRVDKFTLGALEETLKFYLDEEKAIANIPTLKMISMPKEEILRKAEKLKSMIEKEVDLNMEIVESQSEVGGGAYPLD
KLDSYSIAIKPDMKVSEFERGLRLSKDHIIGTVHDDTFFMDLRCIFEKDFERIVKVIKLNTILKKMPM

Sequences:

>Translated_468_residues
MGTNLQEMFKKLPQVSEILESEEILQAYEEYPESLIKDSVRESIEFFRNRILNKEEFDFYNKDVIDKAFELMDKNFSPSL
KPVINATGVILHTNLGRSLLNEKVVDNLCKIAGNYSNLEYDLDEGKRGSRYVHAVELLKRITKAEDAVVVNNNASAVFLT
LNTLAQNKEAIISRGELVEVGGSFRISSIMEKSGAKLVEVGSTNKTHMYDYEDNINEETALIMKVHTSNYSVVGFSESVS
GDELRQLCDEKGIHLIEDLGSGSLIDLSKFGLSYERTVKDCINEGIDLVSFSGDKILGGPQAGIIVGKKELISKIKKNQL
LRAFRVDKFTLGALEETLKFYLDEEKAIANIPTLKMISMPKEEILRKAEKLKSMIEKEVDLNMEIVESQSEVGGGAYPLD
KLDSYSIAIKPDMKVSEFERGLRLSKDHIIGTVHDDTFFMDLRCIFEKDFERIVKVIKLNTILKKMPM
>Mature_467_residues
GTNLQEMFKKLPQVSEILESEEILQAYEEYPESLIKDSVRESIEFFRNRILNKEEFDFYNKDVIDKAFELMDKNFSPSLK
PVINATGVILHTNLGRSLLNEKVVDNLCKIAGNYSNLEYDLDEGKRGSRYVHAVELLKRITKAEDAVVVNNNASAVFLTL
NTLAQNKEAIISRGELVEVGGSFRISSIMEKSGAKLVEVGSTNKTHMYDYEDNINEETALIMKVHTSNYSVVGFSESVSG
DELRQLCDEKGIHLIEDLGSGSLIDLSKFGLSYERTVKDCINEGIDLVSFSGDKILGGPQAGIIVGKKELISKIKKNQLL
RAFRVDKFTLGALEETLKFYLDEEKAIANIPTLKMISMPKEEILRKAEKLKSMIEKEVDLNMEIVESQSEVGGGAYPLDK
LDSYSIAIKPDMKVSEFERGLRLSKDHIIGTVHDDTFFMDLRCIFEKDFERIVKVIKLNTILKKMPM

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=463, Percent_Identity=39.7408207343413, Blast_Score=338, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 52829; Mature: 52698

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTNLQEMFKKLPQVSEILESEEILQAYEEYPESLIKDSVRESIEFFRNRILNKEEFDFY
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
NKDVIDKAFELMDKNFSPSLKPVINATGVILHTNLGRSLLNEKVVDNLCKIAGNYSNLEY
CHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEE
DLDEGKRGSRYVHAVELLKRITKAEDAVVVNNNASAVFLTLNTLAQNKEAIISRGELVEV
ECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHCCHHHHHCCCCEEEC
GGSFRISSIMEKSGAKLVEVGSTNKTHMYDYEDNINEETALIMKVHTSNYSVVGFSESVS
CCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCEEEEEEEECCCEEEEECCCCCC
GDELRQLCDEKGIHLIEDLGSGSLIDLSKFGLSYERTVKDCINEGIDLVSFSGDKILGGP
HHHHHHHHHHCCCEEHHHCCCCCEEEHHHHCCCHHHHHHHHHHCCCCEEEECCCEEECCC
QAGIIVGKKELISKIKKNQLLRAFRVDKFTLGALEETLKFYLDEEKAIANIPTLKMISMP
CCCEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHCCC
KEEILRKAEKLKSMIEKEVDLNMEIVESQSEVGGGAYPLDKLDSYSIAIKPDMKVSEFER
HHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHH
GLRLSKDHIIGTVHDDTFFMDLRCIFEKDFERIVKVIKLNTILKKMPM
CCCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GTNLQEMFKKLPQVSEILESEEILQAYEEYPESLIKDSVRESIEFFRNRILNKEEFDFY
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
NKDVIDKAFELMDKNFSPSLKPVINATGVILHTNLGRSLLNEKVVDNLCKIAGNYSNLEY
CHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEE
DLDEGKRGSRYVHAVELLKRITKAEDAVVVNNNASAVFLTLNTLAQNKEAIISRGELVEV
ECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEHHHHHCCHHHHHCCCCEEEC
GGSFRISSIMEKSGAKLVEVGSTNKTHMYDYEDNINEETALIMKVHTSNYSVVGFSESVS
CCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCEEEEEEEECCCEEEEECCCCCC
GDELRQLCDEKGIHLIEDLGSGSLIDLSKFGLSYERTVKDCINEGIDLVSFSGDKILGGP
HHHHHHHHHHCCCEEHHHCCCCCEEEHHHHCCCHHHHHHHHHHCCCCEEEECCCEEECCC
QAGIIVGKKELISKIKKNQLLRAFRVDKFTLGALEETLKFYLDEEKAIANIPTLKMISMP
CCCEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHCCC
KEEILRKAEKLKSMIEKEVDLNMEIVESQSEVGGGAYPLDKLDSYSIAIKPDMKVSEFER
HHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHH
GLRLSKDHIIGTVHDDTFFMDLRCIFEKDFERIVKVIKLNTILKKMPM
CCCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA